Radiotherapy and PGEMOX/GELOX regimen improved prognosis in elderly patients with early-stage extranodal NK/T-cell lymphoma.

abstract：:In the context of discussions on the reproducibility of clinical studies, we reanalyzed a prospective randomized study on the role of splenic irradiation as adjunct to the conditioning for hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML). Between 1986 and 1989, a total of 229 patients ...

journal_title：Annals of hematology

authors： Gratwohl A,Iacobelli S,Bootsman N,van Biezen A,Baldomero H,Arcese W,Arnold R,Bron D,Cordonnier C,Ernst P,Ferrant A,Frassoni F,Gahrton G,Richard C,Kolb HJ,Link H,Niederwieser D,Ruutu T,Schattenberg A,Schmitz N,Torr

更新日期：2016-05-01 00:00:00

abstract：:We describe three cases of acute promyelocytic leukemia (APL) with long-term disease-free survival who developed congestive heart failure (CHF) requiring cardiac transplantation. All three patients presented late-onset cardiotoxicity. Cardiac failure occurred progressively after 31-month, 32-month, and 14-month interv...

journal_title：Annals of hematology

authors： Thomas X,Le QH,Fiere D

更新日期：2002-09-01 00:00:00

abstract：:Transplantation of peripheral blood stem cells (PBSC), positively and/or negatively selected immediately after harvest, has become a widely applied therapeutic option in hematological or oncological patients. The following case of peripheral blood stem cell transplantation represents the first case of successful trans...

journal_title：Annals of hematology

authors： Humpe A,Riggert J,Wolf C,Binder C,Köhler M

更新日期：2001-02-01 00:00:00

abstract：:We report on a patient who was diagnosed as having B-cell chronic lymphocytic leukemia (CLL) with atypical morphology. Flow cytometry disclosed CD5, CD19, and CD23 positivity, an immunophenotype seen mostly in B-CLL. Histology of the spleen and bone marrow suggested a diagnosis of small lymphocytic lymphoma. Upon blas...

journal_title：Annals of hematology

authors： Späth-Schwalbe E,Flath B,Kaufmann O,Thiel G,Brinckmann R,Dietel M,Possinger K

更新日期：2000-04-01 00:00:00

abstract：:Genetic and morphological markers are well-established prognostic factors in acute myeloid leukemia (AML). However, further reliable markers are urgently needed to improve risk stratification in AML. CD318 (CDCP1) is a transmembrane protein which in solid tumors promotes formation of metastasis and correlates with poo...

journal_title：Annals of hematology

authors： Heitmann JS,Hagelstein I,Hinterleitner C,Roerden M,Jung G,Salih HR,Märklin M,Kauer J

更新日期：2020-03-01 00:00:00

abstract：:Patients with primary refractory or relapsed acute myeloid leukemia (AML) who undergo intensive salvage chemotherapy carry a high risk of treatment failure due to infectious complications and early relapses. The study presented here assessed the effect of granulocyte colony-stimulating factor (G-CSF) on the duration o...

journal_title：Annals of hematology

authors： Kern W,Aul C,Maschmeyer G,Kuse R,Kerkhoff A,Grote-Metke A,Eimermacher H,Kubica U,Wörmann B,Büchner T,Hiddemann W

更新日期：1998-09-01 00:00:00

abstract：:To evaluate the outcomes of refractory/relapsed cHL patients after high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT) in Beijing Cancer hospital and to identify the prognostic risk factors. We retrospectively analyzed 115 relapsed/refractory cHL patients who accepted HDCT and ASCT in our can...

journal_title：Annals of hematology

authors： Xie Y,Wang X,Leng X,Zheng W,Ping L,Zhang C,Liu W,Deng L,Wu M,Song Y,Zhu J

更新日期：2020-03-01 00:00:00

abstract：:Repeated courses of HD IVIg are reported to induce stable remission in a significant proportion of adults with chronic refractory ITP. We have treated 14 such patients obtaining a remission rate quite comparable to the 5-10% of spontaneous remission. ...

journal_title：Annals of hematology

authors： Schiavotto C,Ruggeri M,Rodeghiero F

更新日期：1995-02-01 00:00:00

abstract：:Malignant lymphomas are a heterogenous group of malignancies, belonging to the 10 most frequent types of cancers worldwide. In indolent lymphoma only patients with limited stage I/II (Ann Arbor) can be potentially cured by local irradiation. However, about 85% of cases present with advanced stage; for these patients n...

journal_title：Annals of hematology

authors： Buske C,Dreyling H,Unterhalt M,Hiddemann W

更新日期：2004-01-01 00:00:00

abstract：:Reactivation of fetal hemoglobin synthesis in adulthood can be seen in hematological disorders affecting the erythropoietic system. The objective of the present study was to evaluate the incidence and prognostic significance of increased hemoglobin F in patients with myelodysplastic syndrome. Hemoglobin F concentratio...

journal_title：Annals of hematology

authors： Reinhardt D,Haase D,Schoch C,Wollenweber S,Hinkelmann E,v Heyden W,Lentini G,Wörmann B,Schröter W,Pekrun A

更新日期：1998-03-01 00:00:00

abstract：:In Germany, analyses of clinical and laboratory features of patients with acute porphyrias are only available for hereditary coproporphyria (HCP) but not with other acute porphyrias, acute intermittent porphyria (AIP) and variegate porphyria (VP). The aim of the study was to analyze a large cohort of patients with par...

journal_title：Annals of hematology

authors： Bronisch O,Stauch T,Haverkamp T,Beykirch MK,Petrides PE

更新日期：2019-12-01 00:00:00

abstract：:It has been suggested that human mesenchymal stem cells (hMSC) could be used to repair numerous injured tissues. We have studied the potential use of hMSC to limit radiation-induced skin lesions. Immunodeficient NOD/SCID mice were locally irradiated to the leg (30 Gy, dose rate 2.7 Gy/min) using a (60)Co source to ind...

journal_title：Annals of hematology

authors： François S,Mouiseddine M,Mathieu N,Semont A,Monti P,Dudoignon N,Saché A,Boutarfa A,Thierry D,Gourmelon P,Chapel A

更新日期：2007-01-01 00:00:00

abstract：:Approximately 10% of patients with polycythemia vera (PV) transform to acute leukemia (blast phase) at 10 years after initial diagnosis of PV. The bone marrow pathologic, cytogenetic, and molecular features of blast phase have not been well characterized. In this study, we reviewed 422 PV patients over a period of 11 ...

journal_title：Annals of hematology

authors： Hidalgo López JE,Carballo-Zarate A,Verstovsek S,Wang SA,Hu S,Li S,Xu J,Zuo W,Tang Z,Yin CC,Medeiros LJ,Bueso-Ramos CE,Tang G

更新日期：2018-03-01 00:00:00

abstract：:Co-inheritance of triplicated α-genes can alter the clinical and hematological phenotypes of β-thalassemias. We evaluated the phenotypic diversity and transfusion requirements in β-thalassemia heterozygotes, homozygotes, and normal individuals with associated α-gene triplication. Clinical and hematological evaluation ...

journal_title：Annals of hematology

authors： Mehta PR,Upadhye DS,Sawant PM,Gorivale MS,Nadkarni AH,Shanmukhaiah C,Ghosh K,Colah RB

更新日期：2015-12-01 00:00:00

abstract：:Recent studies in iron-depleted women have challenged the current approach of treating iron-deficiency anemia (IDA) with oral iron in divided daily doses. Alternate day dosing leads to more fractional absorption of iron. In this randomized controlled trial, we looked at the efficacy and safety of alternate-day (AD) ve...

journal_title：Annals of hematology

authors： Kaundal R,Bhatia P,Jain A,Jain A,Nampoothiri RV,Mishra K,Jandial A,Goni D,Sandal R,Jindal N,Meshram A,Sharma R,Khaire N,Singh C,Khadwal A,Prakash G,Das R,Varma N,Varma S,Malhotra P,Lad DP

更新日期：2020-01-01 00:00:00

abstract：:Ruxolitinib, a JAK1 and JAK2 inhibitor, has been tested and approved for the treatment of primary and secondary myelofibrosis (MF). Aim of our study is to report safety and efficacy of ruxolitinib in 98 patients affected by MF treated outside clinical trials and collected and treated consecutively by the Lazio Coopera...

journal_title：Annals of hematology

authors： Breccia M,Andriani A,Montanaro M,Abruzzese E,Buccisano F,Cedrone M,Centra A,Villivà N,Celesti F,Trawinska MM,Massaro F,Di Veroli A,Anaclerico B,Colafigli G,Molica M,Spadea A,Petriccione L,Cimino G,Latagliata R

更新日期：2017-03-01 00:00:00

abstract：:The appropriate management of patients with moderate aplastic anemia (mAA) remains to be unclear and controversial. A cohort of 118 patients with mAA received a novel immunosuppressive strategy of cyclosporine alternately combined with levamisole (CSA and LMS regimen), which included 42 newly diagnosed and 76 chronic ...

journal_title：Annals of hematology

authors： Li X,Shao Y,Ge M,Shi J,Huang J,Huang Z,Zhang J,Nie N,Zheng Y

更新日期：2013-09-01 00:00:00

abstract：:The practical usefulness of Helicobacter pylori eradication for immune thrombocytopenia (ITP) patients is still controversial. However, some ITP patients respond to H. pylori eradication. We conducted a multi-center, open label, prospective phase II study to define the efficacy and toxicities of H. pylori eradication ...

journal_title：Annals of hematology

authors： Kim H,Lee WS,Lee KH,Bae SH,Kim MK,Joo YD,Zang DY,Jo JC,Lee SM,Lee JH,Lee JH,Kim DY,Ryoo HM,Hyun MS,Kim HJ,CoOperative Study Group A for Hematology (COSAH).

更新日期：2015-05-01 00:00:00

abstract：:Chronic hepatitis C (CHC) and iron overload are the main causes of liver disease in β-thalassemia major (βTM). There is limited data regarding the course of CHC in this population. All patients (n=144) from the thalassemia centre of the University Hospital of Patras were evaluated (January 1981 to June 2012). Patients...

journal_title：Annals of hematology

authors： Triantos C,Kourakli A,Kalafateli M,Giannakopoulou D,Koukias N,Thomopoulos K,Lampropoulou P,Bartzavali C,Fragopanagou H,Kagadis GC,Christofidou M,Tsamandas A,Nikolopoulou V,Karakantza M,Labropoulou-Karatza C

更新日期：2013-06-01 00:00:00

abstract：:The prognosis of patients with stage III/IV NK/T-cell lymphoma (NTCL) is extremely poor. Although L-asparaginase (L-asp) is effective for NTCL, its significance has not been clearly demonstrated. In addition, there are few studies comparing treatment outcomes in stage III/IV NTCL. This study evaluated the efficacy of ...

journal_title：Annals of hematology

authors： Kim M,Kim TM,Kim KH,Keam B,Lee SH,Kim DW,Lee JS,Jeon YK,Kim CW,Heo DS

更新日期：2015-03-01 00:00:00

abstract：:In a large proportion of patients with mild bleeding disorders (MBDs) no diagnosis can be established by routine coagulation tests. We investigated whether alterations in plasma clot properties account for MBDs of unknown cause. Ninety-five patients with MBDs of unknown origin and 98 age- and sex-matched healthy contr...

journal_title：Annals of hematology

authors： Gebhart J,Laczkovics C,Posch F,Ay C,Reitter-Pfoertner SE,Haslacher H,Muszbek L,Wolberg AS,Pabinger I

更新日期：2015-08-01 00:00:00

abstract：:The clinical targets for which new generations of antithrombotics have been or are currently under clinical development are those associated with a high risk for thromboembolism, (a) patients undergoing general, orthopedic, major abdominal, and cancer surgery, to prevent venous thromboembolism; (b) patients with deep-...

journal_title：Annals of hematology

authors： Beijering RJ,ten Cate H,ten Cate JW

更新日期：1996-04-01 00:00:00

abstract：:The aim of the present study was to investigate the prevalence of chronic idiopathic neutropenia of adults (CINA) among an apparently healthy population born and living on the island of Crete. The study was carried out with 778 subjects, 392 men aged 16-78 years (median 43 years) and 386 women aged 15-79 years (median...

journal_title：Annals of hematology

authors： Papadaki HA,Xylouri I,Coulocheri S,Kalmanti M,Kafatos A,Eliopoulos GD

更新日期：1999-07-01 00:00:00

abstract：:Recommendations for dyslipidemia management aimed at reducing arterial occlusive events (AOEs) have been recently published. So far, no data have been reported on the management of dyslipidemia in chronic myeloid leukemia (CML) patients treated with nilotinib. We investigated 369 CML adult patients, stratified accordi...

journal_title：Annals of hematology

authors： Caocci G,Mulas O,Capodanno I,Bonifacio M,Annunziata M,Galimberti S,Luciano L,Tiribelli M,Martino B,Castagnetti F,Binotto G,Pregno P,Stagno F,Abruzzese E,Bocchia M,Gozzini A,Albano F,Fozza C,Luzi D,Efficace F,Simul

更新日期：2021-01-03 00:00:00

abstract：:We integrated molecular data with available prognostic factors in patients undergoing allogeneic hematopoietic cell transplantation (alloHCT) for myelodysplastic syndrome (MDS) or secondary acute myeloid leukemia (sAML) from MDS to evaluate their impact on prognosis. Three hundred four patients were sequenced for muta...

journal_title：Annals of hematology

authors： Heuser M,Gabdoulline R,Löffeld P,Dobbernack V,Kreimeyer H,Pankratz M,Flintrop M,Liebich A,Klesse S,Panagiota V,Stadler M,Wichmann M,Shahswar R,Platzbecker U,Thiede C,Schroeder T,Kobbe G,Geffers R,Schlegelberger B,Gö

更新日期：2017-08-01 00:00:00

abstract：:Autologous stem cell transplant (ASCT) is an effective treatment for non-Hodgkin lymphoma (NHL). However, recent supply issues and toxicity of carmustine have necessitated a new conditioning regimen. We conducted a multicenter, phase II study of BEB (busulfan, etoposide, and bendamustine) conditioning regimen for ASCT...

journal_title：Annals of hematology

authors： Kim DY,Chung JS,Jo JC,Cho SH,Shin HJ

更新日期：2020-04-01 00:00:00

abstract：:Sickle cell disease (SCD) is a relatively common inherited hemolytic anemia among individuals of African descent. Genetic factors might clarify clinical diversity of the disease and variations in treatment response. Some researchers investigated heme oxygenase-1 (HMOX1) or chemokine receptor 5 (CCR5Δ32) genotypes amon...

journal_title：Annals of hematology

authors： Bakr S,Khorshied M,Talha N,Jaffer KY,Soliman N,Eid K,El-Ghamrawy M

更新日期：2019-08-01 00:00:00

abstract：:Hematopoietic recovery in 115 patients with metastatic breast cancer or metastatic melanoma, enrolled in phase-I studies of recombinant growth factors while undergoing treatment with high-dose chemotherapy with autologous bone marrow support, was examined with assays of bone marrow progenitor cells and peripheral bloo...

journal_title：Annals of hematology

authors： Laughlin MJ,Kirkpatrick G,Sabiston N,Peters W,Kurtzberg J

更新日期：1993-12-01 00:00:00

abstract：:It is often difficult for standard blood banks in Korea to supply adequate amounts of blood for patients with rare phenotype. Moreover, the definition of a blood in need is ambiguous, and much remains to be learned. In this study, we determined the prevalence of various red blood cell (RBC) antigens from a donor viewp...

journal_title：Annals of hematology

authors： Hong YJ,Chung Y,Hwang SM,Park JS,Kwon JR,Choi YS,Kim JN,Lee DH,Kwon SY,Cho NS,Song EY,Park KU,Song J,Han KS

更新日期：2016-05-01 00:00:00

abstract：:We investigated the efficacy and toxicity of the combination of busulfan, cyclophosphamide, and etoposide (Bu/Cy/VP-16) as a preparative regimen prior to autologous hematopoietic stem cell transplantation (ASCT) in patients with Hodgkin's disease (HD) or non-Hodgkin's lymphoma (NHL). Fifty-three patients with recurren...

journal_title：Annals of hematology

authors： Hänel M,Kröger N,Sonnenberg S,Bornhäuser M,Krüger W,Kroschinsky F,Hänel A,Metzner B,Birkmann J,Schmid B,Hoffknecht MM,Fiedler F,Ehninger G,Zander AR

更新日期：2002-02-01 00:00:00