Meningeal and cerebral involvement in multiple myeloma patients.

abstract：:An acute leukemia with an unusual immunophenotype developed in a 17-year-old girl. At the initial presentation, extramedullary involvement was not evident, but with advancing disease, massive splenomegaly and an osteolytic rib tumor developed. The disease was aggressive and refractory to intensive chemotherapeutic reg...

journal_title：Annals of hematology

authors： Ino T,Tsuzuki M,Okamoto M,Shamoto M,Hirano M

更新日期：1999-01-01 00:00:00

abstract：:Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in European adults. We aimed to evaluate time trends in CLL incidence and medical resource utilisation of CLL patients in the UK. We conducted a retrospective, observational cohort analysis using the UK Clinical Practice Research Datalink (CPRD) comprisi...

journal_title：Annals of hematology

authors： Pfeil AM,Imfeld P,Pettengell R,Jick SS,Szucs TD,Meier CR,Schwenkglenks M

更新日期：2015-03-01 00:00:00

abstract：:We tested two Fc gamma receptor I (Fc gamma RI); six Fc gamma RII; and six Fc gamma RIII-specific monoclonal antibodies (mAb) for their capacity to inhibit monocyte and polymorphonuclear granulocyte (PMN) immune phagocytosis which is mediated by Fc gamma R. We used human red blood cells (rbc) coated with hIgG1 or mIgG...

journal_title：Annals of hematology

authors： Flesch BK,Achtert G,Neppert J

更新日期：1997-01-01 00:00:00

abstract：:This study retrospectively analyzed the clinical outcome of 172 children with newly diagnosed severe aplastic anemia (SAA) between January 2008 and April 2018, who received rabbit antithymocyte globulin (ATG) and cyclosporine (CsA) as first-line treatment. The median age at diagnosis was 5 years (range, 1-14). The ove...

journal_title：Annals of hematology

authors： Lan Y,Chang L,Yi M,Cai Y,Feng J,Ren Y,Liu C,Chen X,Wang S,Guo Y,Zhang A,Liu L,Zhang J,Zhu X

更新日期：2021-01-01 00:00:00

abstract：:Isocitrate dehydrogenase IDH 1 and IDH 2 mutations were reported in several cancer forms, especially in hematological malignancies, but were never been investigated in familial aggregation. The aim of this study is to determine whether germline isocitrate dehydrogenase genes mutations are involved.We targeted IDH1 and...

journal_title：Annals of hematology

authors： Hamadou WS,Bourdon V,Létard S,Brenet F,Laarif S,Besbes S,Paci A,David M,Penard-Lacronique V,Youssef YB,Laatiri MA,Eisinger F,Mari V,Gesta P,Dreyfus H,Bonadona V,Dugast C,Zattara H,Faivre L,Noguchi T,Khélif A,Sal

更新日期：2016-12-01 00:00:00

abstract：:Multicentric Castleman's disease (MCD) is a rare systemic lymphoproliferative disorder with too few patient series reported in the literature to have a clear idea about the etiology, outcome and the best treatment available. Systemic reactive amyloidosis is a very rare complication of MCD and its presence worsens the ...

journal_title：Annals of hematology

authors： Gholam D,Vantelon JM,Al-Jijakli A,Bourhis JH

更新日期：2003-12-01 00:00:00

abstract：:African Americans have two- to three-fold higher incidence of multiple myeloma and MGUS compared to other ethnic groups in the USA. Some physicians often perform diagnostic evaluations for plasma cell disorders (PCD) in African American patients on the basis of hematological abnormalities (thrombocytopenia, leucopenia...

journal_title：Annals of hematology

authors： Tun NM,Joseph G,Soe AM,Ford JG

更新日期：2014-06-01 00:00:00

abstract：:MicroRNAs are short noncoding RNAs, known regulators of several signaling pathways cell differentiation and proliferation, development, and apoptosis, which are deregulated in acute leukemia. Mixed lineage leukemia (MLL) gene encodes a protein with histone methyltransferase activity, which is essential for the fine tu...

journal_title：Annals of hematology

authors： Benetatos L,Vartholomatos G

更新日期：2013-11-01 00:00:00

abstract：:Previous studies exploring associations between statin use and risk of multiple myeloma (MM) showed inconsistent results. We searched for articles published in English in databases (PubMed, Web of Science, EMBASE, Medline, and Google Scholar) before October 2019. The multivariate odds ratio (OR)/relative risk (RR) and...

journal_title：Annals of hematology

authors： Zhang P,Liu B

更新日期：2020-08-01 00:00:00

abstract：:Primary mediastinal large B cell lymphomas (MLCL) differ from other diffuse large cell lymphomas, leading to a description as a separate entity in the current World Health Organization classification. Dose intensification improves long-term results, but no standard therapy has been established so far. We investigated ...

journal_title：Annals of hematology

authors： Fietz T,Knauf WU,Hänel M,Franke A,Freund M,Thiel E,East German Study Group on Hematology and Oncology-OSHO.

更新日期：2009-05-01 00:00:00

abstract：:The patient was initially diagnosed as having non-Hodgkin's lymphoma and was cured following treatment with prednisolone, vincristine, daunorubicin, 1-asparaginase, and cyclophosphamide. Seven years and two months later, he developed osteosarcoma in his right femur. He received chemotherapy consisting of methotrexate,...

journal_title：Annals of hematology

authors： Kubota M,Sawada M,Watanabe K,Koishi S,Kataoka A,Usami I,Lin YW,Okuda A,Akiyama Y,Furusho K

更新日期：1997-02-01 00:00:00

abstract：:There is increasing evidence for the role of chronic antigenic stimulation (CS) in the development of cancer. Clinical data, however, are rare as is the information on outcome. In this study, the occurrence of chronic infections (CI) and autoimmune diseases (AI) in patients with malignant lymphoma at diagnosis was ass...

journal_title：Annals of hematology

authors： Vanura K,Späth F,Gleiss A,Le T,Porpaczy E,Skrabs C,Hauswirth A,Fleiss K,Wessely F,Gaiger A,Müllauer L,Jäger U

更新日期：2011-08-01 00:00:00

abstract：:Indolent primary cutaneous B cell lymphomas (PCBCL) generally have a good prognosis, but they often relapse leading in some cases to extracutaneous disease and therefore, to poor survival. We developed a prognostic model to improve the therapeutic approach to these lymphomas. Two hundred and seventeen patients with di...

journal_title：Annals of hematology

authors： Mian M,Marcheselli L,Luminari S,Federico M,Cantonetti M,Sarris AH,Rossi A,Rambaldi A,Frontani M,Devizzi L,Gianni AM,Busetto M,Berti E,Martinelli G,Tsang RW,Ferreri AJ,Pinotti G,Pogliani E,Zucca E,Cortelazzo S

更新日期：2011-04-01 00:00:00

abstract：:Rituximab induces B-cell depletion; therefore, it has been used in the treatment of immune thrombocytopenic purpura (ITP). The aim of this retrospective study was to evaluate the effectiveness of rituximab in the treatment of 89 patients with chronic ITP refractory to several treatments. All the patients had platelet ...

journal_title：Annals of hematology

authors： Peñalver FJ,Jiménez-Yuste V,Almagro M,Alvarez-Larrán A,Rodríguez L,Casado M,Gallur L,Giraldo P,Hernández R,Menor D,Rodríguez MJ,Caballero D,González R,Mayans J,Millán I,Cabrera JR,Multi-institutional Retrospective Spanish

更新日期：2006-06-01 00:00:00

abstract：:Interleukin-6 (IL-6) has been shown to be an inducer of the acute-phase response (APR) and to be involved in the pathogenesis of several disease states, including graft-versus-host disease (GvHD) following allogeneic bone marrow transplantation (BMT). As blood cells of the monocyte lineage are known to be major produc...

journal_title：Annals of hematology

authors： Pechumer H,Wilhelm M,Ziegler-Heitbrock HW

更新日期：1995-06-01 00:00:00

abstract：:Chronic idiopathic neutropenia of adults (CINA) is a granulocytic disorder characterised by the "unexplained" decrease in the number of circulating neutrophils. Serum inflammatory cytokines and chemokines are increased in CINA. In addition, cytokines gene polymorphisms are associated with increased levels of respectiv...

journal_title：Annals of hematology

authors： Addas-Carvalho M,de Paula EV,Lima CS,Saad ST

更新日期：2005-10-01 00:00:00

abstract：:Recently we described a cutaneous T-cell lymphoma expressing the gamma/delta T-cell receptor [5]. The patient suffering from this lymphoma showed low numbers of myeloid and T cells in peripheral blood, while B and NK cells were relatively increased. In vitro culture of the patient's bone marrow (BM) cells revealed a s...

journal_title：Annals of hematology

authors： Wilhelm M,Meyer P,Batram C,Tony HP,Dummer R,Nestle F,Burg G,Wilms K

更新日期：1992-09-01 00:00:00

abstract：:Elevation of echocardiography-determined tricuspid regurgitant jet velocity (TRV) predicts high systolic pulmonary artery pressure. The present study tested the hypotheses that elevated tricuspid regurgitant jet velocity is associated with both hemolysis and hypoxia and abnormal 6-min walk test (6MWT) results. This st...

journal_title：Annals of hematology

authors： Agha H,El Tagui M,El Ghamrawy M,Abdel Hady M

更新日期：2014-07-01 00:00:00

abstract：:Autologous stem cell transplant (ASCT) is an effective treatment for non-Hodgkin lymphoma (NHL). However, recent supply issues and toxicity of carmustine have necessitated a new conditioning regimen. We conducted a multicenter, phase II study of BEB (busulfan, etoposide, and bendamustine) conditioning regimen for ASCT...

journal_title：Annals of hematology

authors： Kim DY,Chung JS,Jo JC,Cho SH,Shin HJ

更新日期：2020-04-01 00:00:00

abstract：:To characterize the clinical features, associated disorders, and treatment of necrobiotic xanthogranuloma (NXG), a rare non-Langerhans cell histiocytosis, we conducted a retrospective review of pathologically confirmed NXG at Mayo Clinic Arizona from 1987 to June 2017. Data on clinical findings, laboratory findings, a...

journal_title：Annals of hematology

authors： Hilal T,DiCaudo DJ,Connolly SM,Reeder CB

更新日期：2018-08-01 00:00:00

abstract：:The requirement of antifungal prophylaxis has not been established in the chemotherapies for malignant lymphoma. This study was conducted to explore the incidence of invasive fungal diseases (IFD) and their risk factors in patients receiving salvage therapies for malignant lymphoma. We retrospectively analyzed 177 con...

journal_title：Annals of hematology

authors： Takaoka K,Nannya Y,Shinohara A,Arai S,Nakamura F,Kurokawa M

更新日期：2014-10-01 00:00:00

abstract：:A 72-year-old-man with night sweats and a low-grade fever was found to have bilateral adrenal enlargement associated with incipient adrenal insufficiency. Without any intervention, these adrenal lesions regressed spontaneously, accompanied by disappearance of clinical symptoms. Seven months later, however, the lesions...

journal_title：Annals of hematology

authors： Fujiwara T,Kawamura M,Sasaki A,Asahi H,Sasou S,Itoh S,Hiramori K

更新日期：2001-09-01 00:00:00

abstract：:A retrospective study of 120 patients with the clinically and histologically established diagnosis of idiopathic (primary) myelofibrosis (IMF) was performed to determine prognostic factors of predictive value, including parameters characterizing the dynamics of hematopoietic cell kinetics. In contrast to previous stud...

journal_title：Annals of hematology

authors： Kvasnicka HM,Thiele J,Regn C,Zankovich R,Diehl V,Fischer R

更新日期：1999-02-01 00:00:00

abstract：:The lymphoplasmocytoid immunocytoma (Waldenström's disease) is a non-Hodgkin's lymphoma of low malignancy. The disease is defined by the production of monoclonal IgM-globulins in the bone marrow. These macroglobulins affect the aggregation of thrombocytes and bind the coagulation factors, which leads not only to hemor...

journal_title：Annals of hematology

authors： Vécsei PV,Kircher K,Egger S,Bettelheim HC

更新日期：1996-07-01 00:00:00

abstract：:Venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), occurs secondary to a number of hereditary and acquired disorders of hemostasis. A recently recognized polymorphism in Factor V (FV) gene H1299R (also named HR2) has been reported to be a possible risk factor for the deve...

journal_title：Annals of hematology

authors： Otrock ZK,Taher AT,Shamseddeen WA,Zaatari G,Bazarbachi A,Mahfouz RA

更新日期：2008-12-01 00:00:00

abstract：:Primary myelofibrosis (PMF)-associated pruritus is often severe and requires treatment. Fifty-one patients with bone marrow-proven PMF with associated pruritus were identified from a primary cohort of patients with PMF (n = 566) seen at our institution. We conducted a retrospective review of the clinical characteristi...

journal_title：Annals of hematology

authors： Vaa BE,Tefferi A,Gangat N,Pardanani A,Lasho TL,Finke CM,Wolanskyj AP

更新日期：2016-06-01 00:00:00

abstract：:Circulating homocysteine is a risk factor of cardiovascular and cerebrovascular events. Hyperhomocysteinemia may be an early indicator for vitamin B12 disorders because cobalamin is a cofactor in the remethylation process of homocysteine. Serum holotranscobalamin (holoTC II) becomes decreased before the development of...

journal_title：Annals of hematology

authors： Serefhanoglu S,Aydogdu I,Kekilli E,Ilhan A,Kuku I

更新日期：2008-05-01 00:00:00

abstract：:An investigation into the effects of irradiation and of the storage time on aging and quality are a relevant issue to ensure the safety and the efficiency of irradiation in the prevention of transfusion-associated graft-versus-host disease (TA-GVHD). In this work, the biochemical properties and alterations presented b...

journal_title：Annals of hematology

authors： Maia GA,Renó Cde O,Medina JM,Silveira AB,Mignaco JA,Atella GC,Cortes VF,Barbosa LA,Santos Hde L

更新日期：2014-05-01 00:00:00

abstract：:We investigated whether human peripheral blood mononuclear cells (PBMC) express prothrombinase following stimulation with bacterial lipopolysaccharide (LPS). LPS-stimulated PBMC devoid of contaminating platelets failed to activate prothrombin directly. Addition of platelets did not result in expression of prothrombina...

journal_title：Annals of hematology

authors： Pejler G,Geczy CL

更新日期：2001-05-01 00:00:00

abstract：:We conducted a phase 2 study with bortezomib, doxorubicin, and dexamethasone (PAD) followed by thalidomide and dexamethasone (TD) in patients with relapsed multiple myeloma (MM). Forty patients were enrolled between November 2005 and October 2007, with follow-up continuing until January 2009. Efficacy could be assesse...

journal_title：Annals of hematology

authors： Lee SS,Suh C,Kim BS,Chung J,Joo YD,Ryoo HM,Do YR,Jin JY,Kang HJ,Lee GW,Lee MH,Shim H,Kim K,Yoon SS,Bang SM,Kim HY,Lee JJ,Park J,Lee DS,Lee JH,Korean Multiple Myeloma Working Party.

更新日期：2010-09-01 00:00:00