当前位置： SCI文献检索 > BEHAVIOURAL BRAIN RESEARCH期刊下所有文献 > Lesions of the midline thalamic nuclei impair classical conditioning under partial but not continuous reinforcement conditions.

Lesions of the midline thalamic nuclei impair classical conditioning under partial but not continuous reinforcement conditions.

Abstract：

:Rabbits with lesions of the midline thalamic nuclei were compared to rabbits with sham lesions on classical eyeblink (EB) and heart rate (HR) conditioning. Separate groups of sham and lesioned animals received either 25, 50 or 100% reinforcement with a periorbital shock unconditioned stimulus. Animals with lesions showed slightly impaired EB conditioning, compared to sham animals, under the partial but not continuous reinforcement schedules. Midline lesions also reduced the magnitude of the decelerative HR conditioned response under partial but not continuous reinforcement conditions. These findings suggest that the midline thalamic nuclei, like the mediodorsal nucleus of the thalamus, process information required for response selection under non-optimal learning conditions.

journal_name

Behav Brain Res

journal_title

Behavioural brain research

authors

Buchanan SL,Powell DA,Beylotte FM 3rd,Penney J

doi

10.1016/s0166-4328(98)00022-9

subject

Has Abstract

pub_date

1998-12-01 00:00:00

pages

49-58

issue

1-2

eissn

0166-4328

issn

1872-7549

pii

S0166-4328(98)00022-9

journal_volume

97

pub_type

杂志文章

相关文献

BEHAVIOURAL BRAIN RESEARCH文献大全
  • Interleukin-1alphabeta gene-deficient mice show reduced nociceptive sensitivity in models of inflammatory and neuropathic pain but not post-operative pain.

    abstract：:The pro-inflammatory cytokine interleukin-1 (IL-1) has been implicated in both inflammatory processes and nociceptive neurotransmission. To further investigate the role of IL-1 in different pain states, gene-disrupted mice lacking both IL-1alpha and IL-1beta genes (IL-1alphabeta (-/-)) were characterized in inflammato...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2005.09.024

    authors： Honore P,Wade CL,Zhong C,Harris RR,Wu C,Ghayur T,Iwakura Y,Decker MW,Faltynek C,Sullivan J,Jarvis MF

    更新日期：2006-02-28 00:00:00

  • Reduction of gastrointestinal serotonin in alloxan-diabetic rats: reversal by 5-hydroxytryptophan treatment.

    abstract：:A rat model of alloxan-induced diabetes was used to investigate the effect of diabetic state on serotonin (5-HT) levels in peripheral body compartments, gastrointestinal (GI) and platelet, and the metabolic response of these compartments to serotonin precursor (5-hydroxytryptophan, 5-HTP) loading in diabetes. In all s...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/0166-4328(96)00124-6

    authors： Cićin-Sain L,Jernej B

    更新日期：1996-01-01 00:00:00

  • Effects of ketamine, dexmedetomidine and propofol anesthesia on emotional memory consolidation in rats: Consequences for the development of post-traumatic stress disorder.

    abstract：:Intensive Care Unit (ICU) or emergency care patients, exposed to traumatic events, are at increased risk for Post-Traumatic Stress Disorder (PTSD) development. Commonly used sedative/anesthetic agents can interfere with the mechanisms of memory formation, exacerbating or attenuating the memory for the traumatic event,...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2017.04.048

    authors： Morena M,Berardi A,Peloso A,Valeri D,Palmery M,Trezza V,Schelling G,Campolongo P

    更新日期：2017-06-30 00:00:00

  • Neonatal tactile stimulation reverses alterations in fine structure of small, but not large myelinated fibers, from the optic nerve of iron-deficient rats: A size-based selectivity.

    abstract：:Iron is the most common micronutrient deficiency in the world and it is most prevalent in young children, exposing their developing brain to inadequate iron levels. The damage related to neuroanatomical parameters is not reversed after iron treatment. However, evidence suggest that tactile stimulation (TS) may offer g...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2019.112357

    authors： Horiquini-Barbosa E,Gibb R,Kolb B,Bray D,Lachat JJ

    更新日期：2020-02-03 00:00:00

  • Nature vs. nurture: can enrichment rescue the behavioural phenotype of BDNF heterozygous mice?

    abstract：:In earlier experiments we have demonstrated that group-housing in a rather impoverished "standard" environment can be a crucial stress factor in male C57Bl/6 mice. The present study aimed at investigating the effect of combining a probable genetic vulnerability--postulated by the "Neurotrophin Hypothesis of Depression...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2008.04.015

    authors： Chourbaji S,Brandwein C,Vogt MA,Dormann C,Hellweg R,Gass P

    更新日期：2008-10-10 00:00:00

  • Modulation of visually evoked responses in units of the ventral lateral geniculate nucleus of the rat by somatic stimuli.

    abstract：:Single unit activity was recorded from the ventral part of the lateral geniculate nucleus (vLGN) in rats anaesthetized with urethane. Most of the cells located laterally in the nucleus were excited by light. The studied vLGN neurones did not respond to electrical stimulation of the tail, but about half of them changed...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/s0166-4328(05)80294-3

    authors： Davidowa H,Albrecht D

    更新日期：1992-09-28 00:00:00

  • Lidocaine reversible inactivation of the median raphe nucleus has no effect on reference memory but enhances working memory versions of the Morris water maze task.

    abstract：:Numerous studies in the past have dealt with the role of serotonergic system lesions in tasks aimed at measurement of cognitive behavior, but the literature concerning the role of serotonin in cognition remains controversial. Rats with electrolytic lesions of the median raphe nucleus (MRN) were found to display a prof...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/s0166-4328(00)00176-5

    authors： Sarihi A,Motamedi F,Naghdi N,Rashidy-Pour A

    更新日期：2000-09-01 00:00:00

  • 22-kHz ultrasonic vocalization in rats as an index of anxiety but not fear: behavioral and pharmacological modulation of affective state.

    abstract：:Ultrasonic vocalization (USV) was found useful for differentiating fear and anxiety in rats. These affective states were established through a Pavlovian conditioning procedure. Danger stimulus, preceding unavoidable tail shock, elicited acute fear. Intertrial situational cues evoked anxiety. A safety signal (SS) indic...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/s0166-4328(02)00321-2

    authors： Jelen P,Soltysik S,Zagrodzka J

    更新日期：2003-04-17 00:00:00

  • Enhanced anxiety follows withdrawal from subchronic exposure to phencyclidine in rats.

    abstract：:Anxiety was assessed in rats treated with 5mg/kg of PCP bid for 7 days. One week after withdrawal, measures were collected in the light/dark apparatus and during exposure to a cat odor. PCP decreased time spent in the lit area and number of contacts with a cat collar. PCP thus amplified rats' fear of unprotected envir...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2006.10.017

    authors： Audet MC,Goulet S,Doré FY

    更新日期：2007-01-25 00:00:00

  • Choice-based assessments outperform traditional measures for chronic depressive-like behaviors in rats after brain injury.

    abstract：:Depression is the most common psychiatric comorbidity to be diagnosed following traumatic brain injury (TBI). In clinical populations, TBI-induced depression may be particularly difficult to treat due to both unique underlying causes and the propensity for treatment resistance. Preclinical assays are needed to charact...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2020.112879

    authors： Frankot M,O'Hearn C,Vonder Haar C

    更新日期：2020-10-01 00:00:00

  • Effect of local 6-OHDA and 5,6-DHT injections into the rat olfactory bulb on neophobia and learned aversion to a novel food.

    abstract：:This study investigated the role of the noradrenergic (NA) and the serotoninergic (5-HT) centrifugal fibers on the olfactory bulb (OB). For this purpose, behavioral responses largely depending on olfactory information were measured in rats after discrete bilateral injections into the OB with either 6-hydroxydopamine (...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/0166-4328(83)90036-0

    authors： Royet JP,Gervais R,Araneda S

    更新日期：1983-12-01 00:00:00

  • Activation of the ventral subiculum reinvigorates behavior after failure to achieve a goal: Implications for dopaminergic modulation of motivational processes.

    abstract：:Previous studies confirm that brief electrical stimulation of glutamatergic afferents from the ventral subiculum (vSub) can significantly enhance dopamine release in the ventral striatum for an extended duration (>20 min). However, the functional significance of this effect on motivated behavior remains to be specifie...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2018.09.002

    authors： Lindenbach D,Seamans JK,Phillips AG

    更新日期：2019-01-01 00:00:00

  • Nigral 5-HT and substance P-induced enhancement of passive avoidance retention.

    abstract：:Peripheral, posttraining injection of substance P (SP) has been shown to facilitate the retention of aversive and appetitive learning tasks, suggesting that SP may play a role in information processing. In addition, SP may modulate the release of nigrostriatal monoamines, which have also been linked with avoidance lea...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/0166-4328(88)90063-0

    authors： Pelleymounter MA,Schlesinger K,Wehner J,Hall ME,Stewart JM

    更新日期：1988-07-01 00:00:00

  • Comparisons of hemi-inattention produced by unilateral lesions of the posterior parietal cortex or medial agranular prefrontal cortex in rats: neglect, extinction, and the role of stimulus distance.

    abstract：:Neglect in human and non-human primates has been demonstrated following unilateral lesions of both posterior parietal and prefrontal areas. While it has now been well established that a unilateral lesion of the rodent analog of dorsolateral prefrontal cortex, medial agranular cortex (AGm), results in neglect, the effe...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/0166-4328(93)90070-7

    authors： King VR,Corwin JV

    更新日期：1993-04-30 00:00:00

  • The neuroprotective effect of vitamin E on chronic sleep deprivation-induced memory impairment: the role of oxidative stress.

    abstract：:Sleep deprivation induces oxidative stress and impairs learning and memory processes. Vitamin E, on the other hand, is a strong antioxidant that has neuroprotective effect on the brain. In this study, we examined the potential protective effect of chronic administration of vitamin E on chronic sleep deprivation-induce...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2011.09.017

    authors： Alzoubi KH,Khabour OF,Rashid BA,Damaj IM,Salah HA

    更新日期：2012-01-01 00:00:00

  • The behavioural and pathophysiological effects of the ketogenic diet on mild traumatic brain injury in adolescent rats.

    abstract：:Mild traumatic brain injury (mTBI), caused by an insult to the head, results in a cascade of molecular imbalance that includes altered glucose metabolism, mitochondrial dysfunction, and increases in reactive oxygen species. Although glucose is the primary energy source for the brain, it becomes an inefficient substrat...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2019.112225

    authors： Salberg S,Weerwardhena H,Collins R,Reimer RA,Mychasiuk R

    更新日期：2019-12-30 00:00:00

  • Sex differences in spatial memory using serial and search tasks.

    abstract：:The present study assessed the spatial abilities of male and female human participants using different versions of the non-navigational Corsi block-tapping test (CBT) and a search task. Males performed significantly better than females on the standard manual version of the CBT; however, the standard CBT does not allow...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2013.09.027

    authors： Shah DS,Prados J,Gamble J,De Lillo C,Gibson CL

    更新日期：2013-11-15 00:00:00

  • Mnemonic functions of dorsal striatum and hippocampus in aversive conditioning.

    abstract：:These experiments examined the mnemonic functions of hippocampus and dorsal striatum in Pavlovian aversive conditioning. Rats were trained in a single session by presenting three paired tones and footshocks. Immediately after training, they were given microinjections of D-amphetamine or vehicle into either dorsal hipp...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/s0166-4328(02)00402-3

    authors： White NM,Salinas JA

    更新日期：2003-06-16 00:00:00

  • The effect of long-term high frequency repetitive transcranial magnetic stimulation on working memory in schizophrenia and healthy controls--a randomized placebo-controlled, double-blind fMRI study.

    abstract：:In schizophrenia patients negative symptoms and cognitive impairment often persist despite treatment with second generation antipsychotics leading to reduced quality of life and psychosocial functioning. One core cognitive deficit is impaired working memory (WM) suggesting malfunctioning of the dorsolateral prefrontal...

    journal_title：Behavioural brain research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.bbr.2012.09.034

    authors： Guse B,Falkai P,Gruber O,Whalley H,Gibson L,Hasan A,Obst K,Dechent P,McIntosh A,Suchan B,Wobrock T

    更新日期：2013-01-15 00:00:00

  • Post-weaning handling attenuates isolation-rearing induced disruptions of prepulse inhibition in rats.

    abstract：:Isolation rearing is a developmentally specific non-pharmacological manipulation in rats that produces a deficit in sensorimotor gating, as measured by prepulse inhibition (PPI) of the startle reflex. Previous research has demonstrated that the isolation rearing effect on PPI is sensitive to several factors, including...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/s0166-4328(00)00374-0

    authors： Krebs-Thomson K,Giracello D,Solis A,Geyer MA

    更新日期：2001-05-01 00:00:00

  • Cognitive deficits in the rat chronic mild stress model for depression: relation to anhedonic-like responses.

    abstract：:The chronic mild stress (CMS) protocol is widely used to evoke depressive-like behaviours in laboratory rats. The aim of the present study was to examine the effects of chronic stress on cognitive performance. About 70% of rats exposed to 7 weeks of chronic mild stress showed a gradual reduction in consumption of a su...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2008.10.039

    authors： Henningsen K,Andreasen JT,Bouzinova EV,Jayatissa MN,Jensen MS,Redrobe JP,Wiborg O

    更新日期：2009-03-02 00:00:00

  • A facilitating role for the primary motor cortex in action sentence processing.

    abstract：:The involvement of the motor system in action language comprehension is a hotly debated topic in cognitive neuroscience and psychology. Recent studies suggest that primary motor cortex (M1) response to action language is context-sensitive rather than automatic and necessary. Specifically, semantic polarity (i.e. affir...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2017.09.019

    authors： Courson M,Macoir J,Tremblay P

    更新日期：2018-01-15 00:00:00

  • Behavioural effects of chronic haloperidol and risperidone treatment in rats.

    abstract：:The therapeutic properties of typical antipsychotic drugs (APDs) such as haloperidol in schizophrenia treatment are mainly associated with their ability to block dopamine D2 receptors. This blockade is accompanied by side effects such as extrapyramidal symptoms (EPS). Atypical APDs such as risperidone have superior th...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2006.04.004

    authors： Karl T,Duffy L,O'brien E,Matsumoto I,Dedova I

    更新日期：2006-08-10 00:00:00

  • A mouse's spontaneous eating repertoire aids performance on laboratory skilled reaching tasks: A motoric example of instinctual drift with an ethological description of the withdraw movements in freely-moving and head-fixed mice.

    abstract：:Rodents display a spontaneous "order-common" pattern of food eating: they pick up food using the mouth, sit on their haunches, and transfer the food to the hands for handling/chewing. The present study examines how this pattern of behaviour influences performance on "skilled-reaching" tasks, in which mice purchase foo...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2017.09.044

    authors： Whishaw IQ,Faraji J,Mirza Agha B,Kuntz JR,Metz GAS,Mohajerani MH

    更新日期：2018-01-30 00:00:00

  • Fornix transected macaques make fewer perseverative errors than controls during the early stages of learning conditional visuovisual discriminations [corrected].

    abstract：:Previous studies with macaque monkeys have found rapid learning to be impaired in both spatial (visuospatial) and non-spatial (visuomotor) associative learning tasks after fornix transection. In order to test theories that posit a general role for the fornix in associative learning, we investigated whether monkeys wit...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2009.08.016

    authors： Kwok SC,Buckley MJ

    更新日期：2009-12-14 00:00:00

  • Neuroticism and self-evaluation measures are related to the ability to form cognitive maps critical for spatial orientation.

    abstract：:Trait neuroticism is suggested to be related to measures of volume and function of the hippocampus, a brain structure located in the medial temporal lobe that is critical for human navigation and orientation. In this study, we assessed whether measures of trait neuroticism and self-concept are correlated with the huma...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2014.06.002

    authors： Burles F,Guadagni V,Hoey F,Arnold AE,Levy RM,O'Neill T,Iaria G

    更新日期：2014-09-01 00:00:00

  • Continuous psychosocial stress stimulates BMP signaling in dorsal hippocampus concomitant with anxiety-like behavior associated with differential modulation of cell proliferation and neurogenesis.

    abstract：:Bone morphogenetic protein (BMP) signaling in the hippocampus regulates psychiatric behaviors and hippocampal neurogenesis in non-stress conditions; however, stress-induced changes in hippocampal BMP signaling have not yet been reported. Therefore, we sought to examine whether psychosocial stress, which induces psychi...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2020.112711

    authors： Mori M,Murata Y,Tsuchihashi M,Hanakita N,Terasaki F,Harada H,Kawanabe S,Terada K,Matsumoto T,Ohe K,Mine K,Enjoji M

    更新日期：2020-08-17 00:00:00

  • Simvastatin prevents morphine antinociceptive tolerance and withdrawal symptoms through antioxidative effect and nitric oxide pathway in mice.

    abstract：:Oxidative stress and the nitric oxide (NO) pathway are involved in the development of opioid analgesic tolerance and dependence. Simvastatin modulates NO and oxidative stress, so the present study aimed to investigate its effect on the development and expression of morphine analgesic tolerance and withdrawal signs in ...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2020.113104

    authors： Houshmand G,Pourasghar M,Shiran M,Arab Firozjae A,Goudarzi M,Manouchehr F,Shirzad S,Assadpour S,Nikbakht J,Ghorbanzadeh B

    更新日期：2021-01-05 00:00:00

  • Amygdalar orexinergic-GABAergic interactions regulate anxiety behaviors of the Syrian golden hamster.

    abstract：:At present neurobiological interests are directing more attention towards the major role of the amygdalar GABA(A) receptor on orexin-dependent behaviors. This telencephalic region has been widely studied especially in view of its control on various psychiatric disorders such as anxiety and depression. Recently, cross-...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/j.bbr.2010.11.014

    authors： Avolio E,Alò R,Carelli A,Canonaco M

    更新日期：2011-04-15 00:00:00

  • Early social stress in female guinea pigs induces a masculinization of adult behavior and corresponding changes in brain and neuroendocrine function.

    abstract：:This study was undertaken to investigate, in guinea pigs, the effects of pre- and early postnatal social stress on the functioning of hormonal-, autonomic-, behavioral-, and limbic-brain systems. Dams had either lived in groups with a constant composition (i.e. stable social environment) or in groups with changing com...

    journal_title：Behavioural brain research

    pub_type： 杂志文章

    doi：10.1016/s0166-4328(03)00077-9

    authors： Kaiser S,Kruijver FP,Swaab DF,Sachser N

    更新日期：2003-09-15 00:00:00