Abstract：
:This study investigated the role of the noradrenergic (NA) and the serotoninergic (5-HT) centrifugal fibers on the olfactory bulb (OB). For this purpose, behavioral responses largely depending on olfactory information were measured in rats after discrete bilateral injections into the OB with either 6-hydroxydopamine (6-OHDA) or 5,6-dihydroxytryptamine (5,6-DHT) solutions. The evaluation of the level of endogenous 5-HT in the OB was measured by high performance liquid chromatography. The NA fibers appeared lesioned after the 6-OHDA treatment only, whereas the 5-HT level was significantly reduced in 5,6-DHT treated bulbs only (34% of the control value). The animals were fed on usual stock-diet (S) and had the choice between S and a novel food (V) on neophobia test, and again on the following day after aversive conditioning (0.9 mEq/kg LiCl i.p.). The behavioral results showed that the drug administrations were followed by a significant effect in one case only: the intake of V was significantly enhanced in 6-OHDA treated animals during neophobia test. Thus, neophobia was reduced by 6-OHDA. The data are interpreted as follows: (1) the lesion of the bulbar NA or 5-HT fibers does not induce total anosmia; and (2) the NA innervation of the OB could play a role in the modulation of behavioral responses to biological odorants.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Royet JP,Gervais R,Araneda Sdoi
10.1016/0166-4328(83)90036-0subject
Has Abstractpub_date
1983-12-01 00:00:00pages
297-309issue
2-3eissn
0166-4328issn
1872-7549pii
0166-4328(83)90036-0journal_volume
10pub_type
杂志文章abstract：:By the second postnatal week of life infant rats can acquire taste avoidance induced by amphetamine. Psychostimulant drugs supports appetitive and aversive learning in adult rats. Their appetitive effects are more likely to become associated with contextual cues, while the aversive ones have been consistently found in...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.03.018
更新日期：2012-05-16 00:00:00
abstract：:The anterior forebrain pathway of the avian song system is involved in juvenile song learning, but its function in adult song behavior is not known. This report uses lesions to study the role of a particular forebrain nucleus, IMAN, in the seasonal regeneration of song in adult white-crowned sparrows (Zonotrichia leuc...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(98)00011-4
更新日期：1998-11-01 00:00:00
abstract：:The aim of present research was to analyze the temporal structure of rodent's anxiety-related behavior in hole-board apparatus (HB). Fifteen male Wistar rats were tested for 10 min. Video files, collected for each subject, were coded by means of a software coder and event log files generated for each subject. To asses...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2009.11.013
更新日期：2010-03-17 00:00:00
abstract：:In this study the relationship between 6-hydroxydopamine lesions of dopaminergic innervation of the lateral septum and schedule-induced polydipsia was examined. Animals with lesions were found to have a significant increase in water intake during a test involving an intermittent schedule of food delivery. Additional e...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(85)90012-9
更新日期：1985-01-01 00:00:00
abstract：:BALB/cJ and C57BL/6J inbred mouse strains have been proposed as useful models of low and high levels of sociability (tendency to seek social interaction), respectively, based primarily on behaviors of ∼30-day-old mice in the Social Approach Test (SAT). In the SAT, approach and sniffing behaviors of a test mouse toward...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.08.051
更新日期：2013-01-15 00:00:00
abstract：:Although human spatial cognition is at the focus of intense research efforts, experimental evidence on how search strategies differ among age and gender groups remains elusive. To address this problem, we investigated the interaction between age, sex, and strategy usage within a novel virtual water maze-like procedure...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2009.11.022
更新日期：2010-03-17 00:00:00
abstract：:Disruption of conditioned taste aversion (CTA) by tetrodotoxin (TTX) blockade of parabrachial nuclei elicited after ingestion of the gustatory CS and before administration of the visceral US is revealed by unchanged CS preference in retrieval test performed two days after acquisition. The universality of the above amn...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(94)90060-4
更新日期：1994-01-31 00:00:00
abstract：:Levels of weight gain have hit an epidemic level with rates of overweight and obesity diagnoses topping all-time highs. Elevated body weight has been linked to increased rates of cardiac problems, blood pressure issues, and risk of developing type 2 diabetes. Leptin, a hormone produced by the body that is involved in ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2020.112507
更新日期：2020-04-06 00:00:00
abstract：:Complex, multicomponent excitatory postsynaptic potentials (EPSPs) of the red nucleus rubrospinal neurons evoked by stimulation of the sensorimotor cortex and associative field of the parietal cortex were studied in acute experiments on pentobarbitalized cats by the intracellular recording technique. Complex cortical ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(88)90089-7
更新日期：1988-04-01 00:00:00
abstract：:The incidence of stress and stress-related disorders with the transition to motherhood, such as postpartum depression, is estimated to be 20%. Selective serotonin reuptake inhibitor (SSRI) medications are currently the antidepressant of choice to treat maternal mood disorders. However, little is known about the effect...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2011.11.043
更新日期：2012-03-01 00:00:00
abstract：:The present study investigated the impact of a spared nerve injury (SNI) on the daily performance of rats tested in two instrumental conditioning procedures: the progressive ratio (PR) schedule of food reinforcement to study motivation for an appetitive stimulus, and the 5-choice serial reaction time task (5-CSRTT), a...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.02.050
更新日期：2015-06-01 00:00:00
abstract：:Previous studies in our laboratory have demonstrated that piperine produced antidepressant-like action in various mouse models of behavioral despair. This study aimed to investigate the role of brain-derived neurotrophic factor (BDNF) signalling in the antidepressant-like effect of piperine in mice exposed to chronic ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2013.12.020
更新日期：2014-03-15 00:00:00
abstract：:Fetal ethanol experience generates learning and memories capable to increase ethanol consummatory behaviors during infancy. Opioid system seems to be involved in mediating those alcohol-related behaviors. In this work, we proposed to study the impact of prenatal exposure to a moderate ethanol dose, upon ingestion of t...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.111908
更新日期：2019-08-05 00:00:00
abstract：:Chronic morphine exposure induces physical dependence and tolerance. Previous studies have shown that there is a decrease in met-enkephalin levels in states of morphine physical dependence, and that increasing enkephalin during opiate physical withdrawal ameliorates the severity of the morphine withdrawal syndrome. In...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2008.08.005
更新日期：2009-01-30 00:00:00
abstract：:The role of dopamine (DA) receptors in spatial memory consolidation has been demonstrated in numerous brain regions, among others in the nucleus accumbens which innervates the ventral pallidum (VP). The VP contains both D1 and D2 DA receptors. We have recently shown that the VP D1 DA receptor activation facilitates co...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.07.007
更新日期：2016-10-15 00:00:00
abstract：:The complexity of the brain, in which different neuronal cell types are interspersed and complexly interconnected, has posed a major obstacle in identifying pathophysiological mechanisms underlying prevalent neurological disorders. This is largely based in the inability of classical experimental approaches to target d...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/j.bbr.2013.07.007
更新日期：2013-10-15 00:00:00
abstract：:The effects of 0.1 mg/kg dose of haloperidol on self-stimulation were assessed in rats having 3 stable self-stimulation response rates of approximately 10, 50 and 100 responses per min generated by 3 levels of current intensity. Haloperidol reduced overall response rates at all current intensities and generated extinc...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(83)90045-1
更新日期：1983-12-01 00:00:00
abstract：:Voice disorders manifest in the early stages of Parkinson disease (PD), suggesting the vulnerability of the laryngeal sensorimotor system to mild alterations in dopamine signaling. Previous research has demonstrated that manipulations of central dopamine result in acoustic changes in rat ultrasonic vocalization (USV) ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2013.06.006
更新日期：2013-09-01 00:00:00
abstract：:The influence of early experience and strain differences on auditory discrimination learning, open field behaviour and brain size was investigated in wild-type Mongolian gerbils (strain Ugoe:MU95) raised in the wild (wild F-0) or in the laboratory (wild F-1) and in domesticated Laboratory Gerbils (LAB). Adult males we...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2006.05.025
更新日期：2006-10-02 00:00:00
abstract：:Various studies suggest that some sleep functions, especially some slow wave sleep functions, are indispensable in mammals and related to brain regulation. It has been proposed that two of these functions are the adjustment of emotional balance and the processing of acquired emotional memories. During waking, the grad...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/0166-4328(95)00005-e
更新日期：1995-07-01 00:00:00
abstract：:SPAK/STK39 is a mammalian protein kinase involved in the regulation of inorganic ion transport mechanisms known to modulate GABAergic neurotransmission in the both central and the peripheral nervous systems. We have previously shown that disruption of the gene encoding SPAK by homologous recombination in mouse embryon...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2009.12.005
更新日期：2010-04-02 00:00:00
abstract：:The hippocampus plays a vital role in processing contextual memories and reward related learning tasks, such as conditioned place preference (CPP). Among the neurotransmitters in the hippocampus, dopamine is deeply involved in reward-related processes. This study assessed the role of D1- and D2-like dopamine receptors...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.06.061
更新日期：2016-10-01 00:00:00
abstract：:Progression through neuronal loss of substantia nigra pars compacta (SNpc) with Parkinson's disease depends on various protein post-translational modifications mainly comprising ubiquitination. Although many ubiquitination sites have been identified through site-specific methods, systematic quantitative proteomic anal...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112436
更新日期：2020-02-17 00:00:00
abstract：INTRODUCTION:Visuospatial neglect can occur in peripersonal and extrapersonal space. The dorsal visual pathway is hypothesized to be associated with peripersonal, and the ventral pathway with extrapersonal neglect. We aimed to evaluate neural substrates of peripersonal versus extrapersonal neglect, separately for egoce...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2018.06.010
更新日期：2019-01-01 00:00:00
abstract：:We studied the impact of aging during sleep in the rat models of Alzheimer's (AD) and Parkinson's (PD) disease cholinergic neuropathology to determine the possible different and earlier onset of age-related sleep disorder during the neurodegenerative diseases vs. healthy aging. We used the bilateral nucleus basalis (N...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.12.046
更新日期：2016-03-15 00:00:00
abstract：:Different strategies can be used to carry dopamine into the brain such as L-Dopa precursors or galactosilated form of DA (GAL-DA). The aim of this study was to investigate whether GAL-DA would reduce hyperactivity and increase non-selective attention (NSA) in a mouse model of attention deficit hyperactivity disorder (...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2007.10.007
更新日期：2008-03-05 00:00:00
abstract：:Male rats both eat more and weigh more than females. Differences in food intake and body weight result, at least partly, from differences in gonadal hormone secretions. The present experiments were designed to investigate whether sex differences in food motivation might contribute to the behavioral differences observe...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(88)90118-0
更新日期：1988-03-01 00:00:00
abstract：:The lighting environment where the baby born prematurely is placed is different from that experienced in utero. As early exposure to light may affect the immature visual system we have attempted to quantify the neonatal ocular light dose. Lighting surveys performed in 7 neonatal units (NNUs) suggested that mean unit i...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/s0166-4328(05)80193-7
更新日期：1992-07-31 00:00:00
abstract：:Changes in target visibility may be produced by additional stimulus elements at adjacent locations. Such contextual effects may reflect lateral interactions of stimulus representations in early cortical areas. It has been reported that the organization of orientation preference found in primates and cats visual cortex...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2017.07.046
更新日期：2017-09-29 00:00:00
abstract：:The structural characteristics of the area postrema, its anatomical connections, participation in the detection of emesis-provoking substances and the effects of area postrema lesions on taste aversion learning acquisition, are all factors which speak in favor of a role as a chemoreceptor zone involved in the detectio...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(88)90172-6
更新日期：1988-10-01 00:00:00
