Abstract:
:The structural characteristics of the area postrema, its anatomical connections, participation in the detection of emesis-provoking substances and the effects of area postrema lesions on taste aversion learning acquisition, are all factors which speak in favor of a role as a chemoreceptor zone involved in the detection of aversive agents which act as effective inducers of taste aversion learning. The feasibility of substituting electrical intracerebral stimulation of the area postrema for the aversive stimulus was investigated in a taste aversion learning paradigm. In Expt. 1, 0.1-ms rectangular pulses of 50 Hz, delivered intermittently or continuously for 4 h after a 15-min delay following ingestion of the gustatory stimulus, produced reliable learning. Expt. 2 showed the learning thus induced to reflect all the characteristics features attributed to taste aversion learning: one-trial learning, long interstimulus delay and cue-consequence specificity. These results suggest that the area postrema could participate in the detection of the aversive consequences of particular taste aversion learning-inducing agents.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Gallo M,Arnedo M,Agüero A,Puerto Adoi
10.1016/0166-4328(88)90172-6subject
Has Abstractpub_date
1988-10-01 00:00:00pages
289-96issue
3eissn
0166-4328issn
1872-7549pii
0166-4328(88)90172-6journal_volume
30pub_type
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