Abstract：
:Increasingly, research suggests a role for dopamine D1 receptors in the consolidation of extinction of both appetitive and aversive memories. However, a role for D1 receptors in extinction of memories involving drug reward has yet to be established. Here we show that post-retrieval, but not delayed, systemic administration of the D1 receptor antagonist SCH23390 results in prolonged extinction of cocaine conditioned place preference (CPP), suggesting a critical role for D1 receptors in the consolidation of extinction of cocaine-cue memories.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Fricks-Gleason AN,Khalaj AJ,Marshall JFdoi
10.1016/j.bbr.2011.08.019subject
Has Abstractpub_date
2012-01-01 00:00:00pages
357-60issue
1eissn
0166-4328issn
1872-7549pii
S0166-4328(11)00608-5journal_volume
226pub_type
杂志文章abstract：:Herein, we investigated the effect Salvia sahendica (S. sahenica) extract, an endemic plant of Iran on the improvement of learning and memory deficits in amyloid beta-(Aβ) injected rats. In order to test this hypothesis, we pretreated rats with S. sahendica 1 week prior to Aβ injection, then performed Morris water maz...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.11.026
更新日期：2013-03-15 00:00:00
abstract：:Working memory (WM) refers to the short-term maintenance of information with higher cognitive functions. Recent researches show that local field potentials (LFPs) and spikes, as different modes of neural signals, encode WM, respectively. There is a growing interest in how these two signals encode WM in coordination. T...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2013.12.030
更新日期：2014-03-15 00:00:00
abstract：:Sexual imprinting is an early learning process by which young birds acquire the characteristics of a potential sexual partner. The physiological basis of this learning process is an irreversible reduction of dendritic spines in two forebrain areas, the LNM (lateral nido-mesopallium) and the MNM (medial nido-mesopalliu...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2006.03.034
更新日期：2006-07-15 00:00:00
abstract：:Systemic administration of dopamine (DA) D1 (SCH23390: SCH) and D2 (raclopride: RAC) antagonists blocked both acquisition and expression of fructose-conditioned flavor preferences (CFP). It is unclear what brain circuits are involved in mediating these effects. The present study investigated DA signaling within the nu...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.05.004
更新日期：2012-08-01 00:00:00
abstract：:Rats with hippocampal aspiration lesions (HIPP), cortical control lesions (CORT) or sham operations (SHAM) were trained on a delayed alternation GO/NO-GO task, in which responding was reinforced on odd-numbered GO trials but was not reinforced on even-numbered NO-GO trials. The number of responses required to obtain r...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(05)80250-5
更新日期：1992-03-15 00:00:00
abstract：:Rats were trained to reach for food pellets, which varied in size from 20 to 300 mg, from one of 21 locations on a shelf located just outside a test cage. After a barrier was lifted, giving access to a food pellet, latency to contact the food was timed, number of reaches to contact the food were counted, the distance ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(89)80067-1
更新日期：1989-02-01 00:00:00
abstract：:Accumulating evidence shows that stressful events evoke molecular alterations in the brain, considered a pathology in major depressive disorder (MDD). However, the abnormalities of neurotransmissions as well as intracellular signaling pathways affected by chronic stress in brain have not been fully explored. We invest...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112053
更新日期：2019-10-17 00:00:00
abstract：:This study of leg flexion conditioning in dogs, which were trained under both avoidance and classical contingencies consecutively, confirmed and extended the results from the Wahlsten and Cole study (In Classical Conditioning II: Current Research and Theory, Appleton Century-Crofts, New York, 1972). Briefly, dogs were...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(95)00174-3
更新日期：1996-05-01 00:00:00
abstract：:It is well known that Alzheimer's disease (AD) is closely related to diabetes mellitus (DM), and AD is also regarded as Type 3 diabetes (T3D). However, the exact link between AD and DM is still unclear. Recently, more and more evidence has shown that glycogen synthase kinase-3β (GSK-3β) may be the potential link betwe...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/j.bbr.2017.11.015
更新日期：2018-02-26 00:00:00
abstract：:The direction and degree of paw preference was studied in male and female mice from the C3H/He, C3H/OuJIco and New Zealand Black (NZB) strains, using the method previously described by Collins. All the populations of mice tested exhibited a low degree of lateralization, which varied among strains: NZB mice were more s...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(05)80185-8
更新日期：1991-10-25 00:00:00
abstract：:Integrating research efforts using a cross-domain approach could redefine traditional constructs used in behavioral and clinical neuroscience by demonstrating that behavior and mental processes arise not from functional isolation but from integration. Our research group has been examining the interface between cogniti...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/j.bbr.2014.05.028
更新日期：2015-01-01 00:00:00
abstract：:The ameliorating effects of the ethyl acetate fraction from Dendropanax morbifera (EFDM) on cognitive impairment in high-fat diet (HFD)-induced diabetic mice were examined by measuring its possible pharmacological activities. Administration of EFDM (20 and 50mg/kg body weight) in HFD-induced diabetic mice significantl...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.06.013
更新日期：2016-10-01 00:00:00
abstract：:Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the HD gene. Besides psychiatric, motor and cognitive symptoms, HD patients suffer from sleep disturbances. In order to screen a rat model transgenic for HD (tgHD rats) for sleep-wake cycle dysregulation, we monitored their c...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2009.06.031
更新日期：2009-12-14 00:00:00
abstract：:Relapse to drug use following prolonged periods of abstinence results, in part, from the ability of contextual cues paired previously with self-administered drug to elicit drug craving and -seeking behavior. Given the popularity of the mouse for the genetic analysis of drug-induced behaviors, a place conditioning mode...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(02)00102-x
更新日期：2002-10-17 00:00:00
abstract：:The spontaneously hypertensive rat (SHR) has been used as a genetic animal model of attention deficit/hyperactivity disorder (ADHD). SHR/Izm is derived from stroke-resistant SHR as SHR/NIH and SHR/NCrl but from 22nd to 23rd generation descendants of the SHR/NIH ancestor and therefore may show different behavioral phen...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.08.026
更新日期：2014-11-01 00:00:00
abstract：:Spinal trigeminal nucleus pars oralis (SpoV) is anatomically linked to brain circuitry thought to subserve unconditioned and conditioned nictitating membrane responses in rabbit. Single-unit recording from SpoV and adjacent reticular formation obtained during conditioning from awake, behaving animals revealed modulati...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(05)80024-5
更新日期：1991-08-29 00:00:00
abstract：:Recently, several studies have shown different conclusions regarding the effect of oxytocin (OT) on the social behaviors of male mice. Most of these studies used exogenous OT, but currently, investigations of the neural bases of social behavior are increasingly employing gene inactivation. This study aimed to analyze ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2013.01.025
更新日期：2013-05-01 00:00:00
abstract：:In the present study, the velocity of pointing movements towards visual targets was analyzed. In accordance with the literature, tangential velocity was found to exhibit rather smooth, single-peaked profiles. In contrast, however, the profiles of the velocity components in the Cartesian coordinates of space were consp...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(90)90030-i
更新日期：1990-08-20 00:00:00
abstract：:Regional cerebral blood flow (rCBF) was studied in a task, where a preparatory stimulus (S1) cued for an imperative second stimulus (S2) which was associated with a response. Two preparatory stimuli cued unequivocally each for one response. In contrast, a third preparatory stimulus cued for two response alternatives w...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2005.05.014
更新日期：2005-09-08 00:00:00
abstract：:The role of mitochondrial dysfunction has been well-documented in Alzheimer's disease (AD). Glucagon-like peptide 1 (GLP-1) receptor agonists are being utilized as neuroprotectants in the treatment of various neurological disorders, including AD. We conducted this study to explore the effects of exenatide (a GLP-1 rec...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.111932
更新日期：2019-09-16 00:00:00
abstract：:With increasing age comes an increased risk for sustaining traumatic brain injuries (TBI). However, the effect of age is rarely studied in animal models of TBI. The present study evaluated the effect of increased age on recovery of function following bilateral medial frontal cortex injury. Groups of young (3 months) a...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2003.11.012
更新日期：2004-08-12 00:00:00
abstract：:Continuing previous efforts to develop the 4-vessel occlusion (4-VO) model of chronic cerebral hypoperfusion (CCH), here we evaluated whether permanent, stepwise 4-VO causes both learning deficits, hippocampal neurodegeneration and retinal lesion in young, middle-aged or aged rats. Chronic 4-VO was induced by ligation...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2008.10.023
更新日期：2009-02-11 00:00:00
abstract：:Current estimates indicate that millions of people in the United States abuse opioid drugs, which may also affect their offspring. To determine whether parental exposure to morphine alters reward and affective behaviors in subsequent generations we exposed male and female C57BL/6NTac mice to morphine (75 mg) or placeb...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2020.112842
更新日期：2020-10-01 00:00:00
abstract：:Sex steroids exert potent effects on mood and mental state in the human. Our previous experimental findings in female rats suggest that these effects may be mediated, in part, by the action of estrogen on the 5-hydroxytryptamine2A receptor (5-HT(2A)R) and serotonin transporter (SERT) in brain. Here we review our recen...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/s0166-4328(99)00082-0
更新日期：1999-11-01 00:00:00
abstract：INTRODUCTION:Several human studies have reported that coffee consumption improves cognitive performance. In the present study, we investigated whether instant decaffeinated coffee also ameliorates cognitive performance and attenuates the detrimental effects of scopolamine on memory. METHODS:Memory performance was eval...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2013.02.003
更新日期：2013-05-15 00:00:00
abstract：:Autism is a heterogeneous, behaviorally defined developmental disorder with unknown etiology but thought to be the result of environmental insult acting upon the developing brain of a genetically susceptible individual. Approximately 30% of individuals with autism have normal development up to the age of about 30 mont...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2010.02.032
更新日期：2010-07-11 00:00:00
abstract：:Astrocyte dysfunction is implicated in clinical depression. There is a paucity of animal models to assess the role of astrocytes in depression pathogenesis. Refinement of an existing model is described here. Administration of the astrocytic toxin L-alpha aminoadipic acid (L-AAA) to the pre-limbic cortex (PLC) was asse...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.01.015
更新日期：2019-04-19 00:00:00
abstract：:Deep brain stimulation (DBS) has gained interest as a potential therapy for advanced treatment-resistant dementia. However, possible targets for DBS and the optimal stimulation parameters are not yet clear. Here, we compared the effects of DBS of the CA1 sub-region of the hippocampus, mammillothalamic tract, anterior ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.06.032
更新日期：2015-10-01 00:00:00
abstract：:Air and light pollution contribute to fetal abnormalities, increase prevalence of cancer, metabolic and cardiorespiratory diseases, and central nervous system (CNS) disorders. A component of air pollution, particulate matter, and the phenomenon of dim light at night (dLAN) both result in neuroinflammation, which has b...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.07.033
更新日期：2015-11-01 00:00:00
abstract：:Pigeons trained to discriminate between visual stimuli in a key-pecking task normally show excellent interocular transfer of training (IOT) when trained with only one eye and then tested with the 'naive' eye. When the dorsal supraoptic decussation (DSO) was sectioned and pigeons were then trained monocularly to peck a...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(85)90076-2
更新日期：1985-07-01 00:00:00
