Abstract:
:In this study the relationship between 6-hydroxydopamine lesions of dopaminergic innervation of the lateral septum and schedule-induced polydipsia was examined. Animals with lesions were found to have a significant increase in water intake during a test involving an intermittent schedule of food delivery. Additional experiments with these animals showed that lesions had no effect on: (i) spontaneous drinking, the amount of drinking after 24 h food or water deprivation, water intake following a hypertonic saline challenge; (ii) eating behavior with or without food deprivation; and (iii) spontaneous locomotor activity. This increase in adjunctive behavior is discussed in the light of an enhanced frustrative effect induced by the septal lesions.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Taghzouti K,Simon H,Tazi A,Dantzer R,Le Moal Mdoi
10.1016/0166-4328(85)90012-9subject
Has Abstractpub_date
1985-01-01 00:00:00pages
1-8issue
1eissn
0166-4328issn
1872-7549pii
0166-4328(85)90012-9journal_volume
15pub_type
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