Abstract：
:Unilateral removals of the posterior insula or of the second somatic sensory projection area (SII) were made in respectively 8 and 6 monkeys. These animals were divided into a 'contralateral' group of 7 with removals from the hemisphere opposite to the preferred hand; and an 'ipsilateral' group of 7 animals with removals from the hemisphere on the same side as the preferred hand. In addition, 6 unoperated monkeys were trained comparably. Both the contralateral and ipsilateral animals were impaired in comparison with unoperated animals at threshold discriminations of graded roughness and/or sizes when using the hand opposite the removals. Animals with contralateral ablations were impaired in comparison with those having ipsilateral ablations only in a few of many instances: with the hand ipsilateral to the removals at re-learning a tactile discrimination and at learning an auditory discrimination; with the hand opposite to the removals when it was initially used on visual or auditory tasks that had already been mastered with the other hand. It is suggested that in addition to SII the insula is also organized asymmetrically in relation to hand preference in the monkey, but the insula of the predominant hemisphere may be involved as much in non-tactual as tactual performances, for example in tasks involving successive discrimination and when a familiar task has to be performed initially with the other hand.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Hörster W,Ettlinger Gdoi
10.1016/0166-4328(87)90011-8subject
Has Abstractpub_date
1987-10-01 00:00:00pages
1-17issue
1eissn
0166-4328issn
1872-7549pii
0166-4328(87)90011-8journal_volume
26pub_type
杂志文章abstract：:The therapeutic properties of typical antipsychotic drugs (APDs) such as haloperidol in schizophrenia treatment are mainly associated with their ability to block dopamine D2 receptors. This blockade is accompanied by side effects such as extrapyramidal symptoms (EPS). Atypical APDs such as risperidone have superior th...
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
pub_type： 杂志文章,评审
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pub_type： 杂志文章
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更新日期：2016-07-15 00:00:00
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pub_type： 杂志文章
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journal_title：Behavioural brain research
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更新日期：2004-12-06 00:00:00
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journal_title：Behavioural brain research
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