Abstract:
:One of the most widely used animal models for assessing recovery of locomotor functioning is the spinal rat. Although true differences in locomotor abilities of these animals are exhibited during treadmill testing, current measurement techniques often fail to detect them. The HiJK (Hillyer-Joynes Kinematics) scale was developed in an effort to distinguish more effectively between groups of spinal rats. Scale items were compiled after extensive review of the literature concerning development and analysis of rat locomotion and a thorough examination of the current tools. Treadmill tests for 137 Sprague-Dawley rats were taped and scored. The structure of the scale was tested with principle components and factor analysis, in which six of the eight items accounted for 59% of the variance, while all eight accounted for 78%. Validity tests demonstrate that HiJK is measuring locomotor performance accurately and powerfully. First, the HiJK scale correlates highly (>.8) with the widely used BBB scale and second, as shown with ANOVA, can distinguish between different groups of spinal rats. Reliability of the scale was also analyzed. Cronbach's alpha was shown to be .91, indicating considerable internal consistency. Additionally, inter-rater and intra-rater reliabilities were substantial, with correlations for most items reaching above .80. We believe that the HiJK scale will help researchers verify existing experimental differences, advance the field of spinal cord research, and, hopefully, lead to discovery of methods to enhance recovery of function.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Hillyer JE,Joynes RLdoi
10.1016/j.bbr.2009.04.009subject
Has Abstractpub_date
2009-09-14 00:00:00pages
291-302issue
2eissn
0166-4328issn
1872-7549pii
S0166-4328(09)00226-5journal_volume
202pub_type
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pub_type: 杂志文章,评审
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journal_title:Behavioural brain research
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journal_title:Behavioural brain research
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更新日期:2008-06-26 00:00:00
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