The relevance of fractional amplitude of low-frequency fluctuation to interference effect.

Abstract:

:Growing evidence has indicated a potential connection between resting-state functional magnetic resonance imaging (RS-fMRI) signal and cognitive performance. However, the relationship between intrinsic neural activity and behavioral interference effect on cognitive control has been poorly understood. In the present study, seventy-eight healthy subjects underwent RS-fMRI and performed Multi-Source Interference Task (MSIT). The fractional amplitude of low-frequency fluctuation (fALFF) was measured as an indicator of intrinsic brain activity. The difference in reaction times between interference and control conditions in MSIT was evaluated as interference effect. Then we examined the associations between fALFF and interference effect using partial correlation analysis controlling for age, gender and mean framewise displacement. The results demonstrated that fALFF values in orbital prefrontal cortex (OPFC) and right inferior frontal cortex (IFC) were negatively correlated with the interference effect in MSIT. The findings manifest that OPFC and right IFC may influence the processing efficiency of cognitive conflict and play a crucial role in cognitive control.

journal_name

Behav Brain Res

authors

Deng Y,Wang Y,Ding X,Tang YY

doi

10.1016/j.bbr.2015.08.014

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

401-407

eissn

0166-4328

issn

1872-7549

pii

S0166-4328(15)30147-9

journal_volume

296

pub_type

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