Biphasic subcellular localization of the DAZL-related protein boule in Drosophila spermatogenesis.

abstract：:The cornea is one of the most densely innervated structures of the body. In the developing chicken embryo, nerves from the ophthalmic trigeminal ganglion (OTG) innervate the cornea in a series of spatially and temporally regulated events. However, little is known concerning the signals that regulate these events. Here...

journal_title：Developmental biology

authors： Kubilus JK,Linsenmayer TF

更新日期：2010-08-01 00:00:00

abstract：:The migration and fate of cranial and vagal neural crest-derived progenitor cells (NCPCs) have been extensively studied; however, much less is known about sacral NCPCs particularly in regard to their distribution in the urogenital system. To construct a spatiotemporal map of NCPC migration pathways into the developing...

journal_title：Developmental biology

authors： Wiese CB,Deal KK,Ireland SJ,Cantrell VA,Southard-Smith EM

更新日期：2017-09-01 00:00:00

abstract：:During the process of gastrulation in the sea urchin embryo, the vegetal plate invaginates to form the archenteron, a long narrow tube that extends across the blastocoel. Rearrangement of cells within the archenteron is thought to be a key component of the process of archenteron elongation. While these cell rearrangem...

journal_title：Developmental biology

authors： Ingersoll EP,Ettensohn CA

更新日期：1994-06-01 00:00:00

abstract：:Lineage specification of multipotent progenitor cells is governed by a balance of lineage-affiliated transcription factors, such as GATA1 and PU.1, which regulate the choice between erythroid and myelomonocytic fates. But how ratios of lineage-determining transcription factors stabilize progenitor cells and resolve th...

journal_title：Developmental biology

authors： Huang S,Guo YP,May G,Enver T

更新日期：2007-05-15 00:00:00

abstract：:Despite undergoing normal development and acquiring normal morphology and motility, mutations in spe-38 or trp-3/spe-41 cause identical phenotypes in Caenorhabditis elegans-mutant sperm fail to fertilize oocytes despite direct contact. SPE-38 is a novel, four-pass transmembrane protein and TRP-3/SPE-41 is a Ca(2+)-per...

journal_title：Developmental biology

authors： Singaravelu G,Chatterjee I,Rahimi S,Druzhinina MK,Kang L,Xu XZ,Singson A

更新日期：2012-05-15 00:00:00

abstract：:The Drosophila melanogaster ventral nerve cord derives from neural progenitor cells called neuroblasts. Individual neuroblasts have unique gene expression profiles and give rise to distinct clones of neurons and glia. The specification of neuroblast identity provides a cell intrinsic mechanism which ultimately results...

journal_title：Developmental biology

authors： Buescher M,Tio M,Tear G,Overton PM,Brook WJ,Chia W

更新日期：2006-04-15 00:00:00

abstract：:A newly defined genetic locus designated lethal (1) optic ganglion reduced (l(1)ogre: 1-18.8, 6E1/2-6E4/5) is characterized. Four alleles have been isolated, one organismal viable and three organismal lethals. Histological analyses of these mutants at the light microscopic level have detected defects only in the devel...

journal_title：Developmental biology

authors： Lipshitz HD,Kankel DR

更新日期：1985-03-01 00:00:00

abstract：:The thisbe (ths) gene encodes a Drosophila fibroblast growth factor (FGF), and mutant females are viable but sterile suggesting a link between FGF signaling and fertility. Ovaries exhibit abnormal morphology including lack of epithelial sheaths and muscle tissues that surround ovarioles. Here we investigated how FGF i...

journal_title：Developmental biology

authors： Irizarry J,Stathopoulos A

更新日期：2015-08-01 00:00:00

abstract：:teashirt (tsh) encodes a zinc-finger protein that is thought to be part of a network that contributes to regionalization of the Drosophila embryo and establishes the domains of Hox protein function. tsh and the Hox gene Sex combs reduced (Scr) are essential to establish the identity of the first thoracic segment. We u...

journal_title：Developmental biology

authors： Taghli-Lamallem O,Gallet A,Leroy F,Malapert P,Vola C,Kerridge S,Fasano L

更新日期：2007-07-01 00:00:00

abstract：:Changes in the intracellular free calcium levels in the cortical region of cleaving Xenopus eggs were examined using semi-synthetic aequorin. We detected periodic oscillations in the free calcium levels accompanying the cleavage cycle as early as the first cleavage onward. The calcium levels began to increase at early...

journal_title：Developmental biology

authors： Kubota HY,Yoshimoto Y,Hiramoto Y

更新日期：1993-12-01 00:00:00

abstract：:Syndecan-3 is one of four identified members of a family of transmembrane proteoglycans (the syndecans) that possess highly similar cytoplasmic and transmembrane domains and may function as extracellular matrix receptors and/or low affinity receptors for signaling molecules such as FGF. We previously reported the clon...

journal_title：Developmental biology

authors： Gould SE,Upholt WB,Kosher RA

更新日期：1995-04-01 00:00:00

abstract：:Cleft palate is one of the most common craniofacial congenital defects in humans. It is associated with multiple genetic and environmental risk factors, including mutations in the genes encoding signaling molecules in the sonic hedgehog (Shh) pathway, which are risk factors for cleft palate in both humans and mice. Ho...

journal_title：Developmental biology

authors： Li J,Yuan Y,He J,Feng J,Han X,Jing J,Ho TV,Xu J,Chai Y

更新日期：2018-09-01 00:00:00

abstract：:Ephrin-B2, a member of the Eph/ephrin family of cell signaling molecules, has been implicated in the guidance of cranial and trunk neural crest cells (NCC) and development of the branchial arches(BA), but detailed examination in mice has been hindered by embryonic lethality of Efnb2 null loss of function due to a requ...

journal_title：Developmental biology

authors： Lewis AE,Hwa J,Wang R,Soriano P,Bush JO

更新日期：2015-10-15 00:00:00

abstract：:In order to disclose the mechanism that regulate synapse development we compared the distributions of agrin, acetylcholine receptors (AChR) and a basal lamina heparan sulfate proteoglycan (HSPG) in sections and cultures prepared from Xenopus laevis and Ambystoma mexicanum embryos. While agrin, AChR and HSPG may accumu...

journal_title：Developmental biology

authors： Anderson MJ,Shi ZQ,Grawel R,Zackson SL

更新日期：1995-07-01 00:00:00

abstract：:The regeneration of lost body parts is a fascinating phenomenon exhibited by some multicellular organisms. In social amoebae, such as Dictyostelium discoideum, the pseudoplasmodium is a temporary migratory multicellular structure with high regeneration ability. It consists of future stalk cells (prestalk cells) at the...

journal_title：Developmental biology

authors： Mohri K,Tanaka R,Nagano S

更新日期：2020-01-01 00:00:00

abstract：:During the development of locomotion circuits it is essential that motoneurons with distinct subtype identities select the correct trajectories and target muscles. In vertebrates, the generation of motoneurons and myelinating glia depends on Olig2, one of the five Olig family bHLH transcription factors. We investigate...

journal_title：Developmental biology

authors： Oyallon J,Apitz H,Miguel-Aliaga I,Timofeev K,Ferreira L,Salecker I

更新日期：2012-09-15 00:00:00

abstract：:Salivary gland formation in the Drosophila embryo is dependent on the homeotic gene Sex combs reduced (Scr). When Scr function is missing, salivary glands do not form, and when SCR is expressed everywhere in the embryo, salivary glands form in new places. Scr is normally expressed in all the cells that form the saliva...

journal_title：Developmental biology

authors： Henderson KD,Andrew DJ

更新日期：2000-01-15 00:00:00

abstract：:In many organisms, like Caenorhabditis elegans and Drosophila melanogaster, establishment of spatial patterns and definition of cell fate are driven by the segregation of determinants in response to spatial cues, as early as oogenesis or fertilization. In these organisms, a family of conserved proteins, the PAR protei...

journal_title：Developmental biology

authors： Vinot S,Le T,Ohno S,Pawson T,Maro B,Louvet-Vallée S

更新日期：2005-06-15 00:00:00

abstract：:A fundamental issue during nervous system development is how individual cells are formed from the undefined precursors. Differentiated neurons and glia, two major cell types mediating neuronal function, are acquired from immature precursors via a series of explicit controls exerted by transcription factors such as pro...

journal_title：Developmental biology

authors： Mao H,Lv Z,Ho MS

更新日期：2012-10-01 00:00:00

abstract：:Peptide growth factors can initiate changes in cell fate in Xenopus ectodermal explants and induce the formation of mesoderm. Marker genes expressed in mesoderm allow the analysis of whether, or how much, induction has occurred, but do not tell us what molecules are involved in carrying out the response. In this repor...

journal_title：Developmental biology

authors： Vize PD

更新日期：1996-07-10 00:00:00

abstract：:Stable subdivision of Drosophila limbs into Anterior (A) and Posterior (P) compartments is a consequence of asymmetric signaling by Hedgehog (Hh) from P to A cells. The activity of the homeodomain protein Engrailed (En) in P cells has been reported to help to generate this asymmetry by inducing the expression of hedge...

journal_title：Developmental biology

authors： Bejarano F,Milán M

更新日期：2009-03-15 00:00:00

abstract：:Early mammalian embryogenesis is controlled by mechanisms governing the balance between pluripotency and differentiation. The expression of early lineage-specific genes can vary significantly between species, with implications for developmental control and stem cell derivation. However, the mechanisms involved in patt...

journal_title：Developmental biology

authors： Niakan KK,Eggan K

更新日期：2013-03-01 00:00:00

abstract：:A follicular cDNA library from Bombyx mori (576 clones) was screened to obtain a representative sample of chorion sequences differentially expressed during the early period of choriogenesis. Ten selected sequences were characterized by Northern analysis and by dot blots of stage-specific RNA. Five of these sequences (...

journal_title：Developmental biology

authors： Eickbush TH,Rodakis GC,Lecanidou R,Kafatos FC

更新日期：1985-12-01 00:00:00

abstract：:Zygote arrest (Zar) proteins are crucial for early embryonic development, but their molecular mechanism of action is unknown. The Translational Control Sequence (TCS) in the 3' untranslated region (UTR) of the maternal mRNA, Wee1, mediates translational repression in immature Xenopus oocytes and translational activati...

journal_title：Developmental biology

authors： Charlesworth A,Yamamoto TM,Cook JM,Silva KD,Kotter CV,Carter GS,Holt JW,Lavender HF,MacNicol AM,Ying Wang Y,Wilczynska A

更新日期：2012-09-15 00:00:00

abstract：:During epithelial development cells become polarized along their apical-basal axis and some epithelia also exhibit polarity in the plane of the tissue. Mutations in the gene encoding a Drosophila Pak family serine/threonine kinase, dPak, disrupt the follicular epithelium that covers developing egg chambers during ooge...

journal_title：Developmental biology

authors： Conder R,Yu H,Zahedi B,Harden N

更新日期：2007-05-15 00:00:00

abstract：:The evolutionary divergence of cnidarian and bilaterian lineages from their remote metazoan ancestor occurred at an unknown depth in time before the Cambrian, since crown group representatives of each are found in Lower Cambrian fossil assemblages. We report here a variety of putative embryonic, larval, and adult micr...

journal_title：Developmental biology

authors： Chen JY,Oliveri P,Gao F,Dornbos SQ,Li CW,Bottjer DJ,Davidson EH

更新日期：2002-08-01 00:00:00

abstract：:The smaller AB-cell of the 2-cell embryo of Tubifex divides 40 min later than the larger CD-cell. The present study was undertaken to elucidate those factors that are responsible for this cleavage asynchrony. An examination of chromosome cycles showed that the AB-cell entered M-phase 5 min later and spent about 35 min...

journal_title：Developmental biology

authors： Shimizu T

更新日期：1993-05-01 00:00:00

abstract：:The location and movement of mammalian gut tissue progenitors, prior to the expression of tissue-specific genes, has been unknown, but this knowledge is essential to identify transitions that lead to cell type specification. To address this, we used vital dyes to label exposed anterior endoderm cells of early somite s...

journal_title：Developmental biology

authors： Tremblay KD,Zaret KS

更新日期：2005-04-01 00:00:00

abstract：:The chick spinal cord can regenerate following injury until advanced developmental stages. It is conceivable that changes in stem/progenitor cell plasticity contribute to the loss of this capacity, which occurs around E13. We investigated the contribution of proliferation, phenotypic changes in radial glia progenitors...

journal_title：Developmental biology

authors： Whalley K,Gögel S,Lange S,Ferretti P

更新日期：2009-08-15 00:00:00

abstract：:The dorsal air sacs supply oxygen to the flight muscles of the Drosophila adult. This tracheal organ grows from an epithelial tube (the air sac primordium (ASP)) that arises during the third larval instar (L3) from a wing-disc-associated tracheal branch. Since the ASP is generated by a program of both morphogenesis an...

journal_title：Developmental biology

authors： Guha A,Kornberg TB

更新日期：2005-11-01 00:00:00