Abstract:
:The aim of this study was to find out by radiological analysis whether it is possible to prevent interval cancers in screening programmes without a concomitant increase in false positives. Re-scrutiny of all mammograms of 544 interval cancers was implemented. Blinded re-scrutiny of screening mammograms of 390 interval cancers mixed with other cases (prevalence of detectable cases 37 %) by two outside radiologists was also carried out. True interval cancers constituted 49 %, missed tumours 25 %, occult tumours 10 % and unclassifiable cases 16 %. There were no significant differences in survival between true interval cancers, overlooked or misinterpreted cancers, and mammographically occult cancers. In the blinded re-scrutiny both examiners reached a positive predictive value for malignancy of 67 %, and a sensitivity of 69 % and 81 %, respectively. In a screening programme such as this, it was estimated that 100-400 additional women would have to be recalled from screening for further workup in order to detect each additional cancer which would otherwise emerge as an interval cancer. The occurrence of interval cancer increased with age and was influenced by the design of screening. The proportion of patients with potential iatrogenic delay in diagnosis (overlooked and misinterpreted cancers) was equivalent to figures from other studies. There were no significant differences in survival between the various categories of interval cancer. The study confirmed the association of criteria for referral for further investigation with the number of false positives. Efforts to reduce the number of interval cancers by lowering the threshold for recall are likely to be counterproductive.
journal_name
Eur Radioljournal_title
European radiologyauthors
Vitak Bdoi
10.1007/s003300050452subject
Has Abstractpub_date
1998-01-01 00:00:00pages
639-46issue
4eissn
0938-7994issn
1432-1084journal_volume
8pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract::The purpose of this paper is to define and evaluate a classification category for contrast-enhanced (CE) MR imaging of the breast based on the BI-RADS mammographic categories of the American College of Radiology. Using five evaluation criteria for MR findings (initial signal increase, post-initial signal behavior, sha...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-001-1213-1
更新日期:2002-05-01 00:00:00
abstract::In the past two decades acquired immunodeficiency syndrome (AIDS) has become one of the most devastating illnesses in human history. As the epidemic continues to spread increasingly, AIDS patients are no longer confined to a few specialized AIDS hospitals and are now seen in general hospitals and clinics everywhere. R...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-003-2065-7
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To quantify radiation dose reduction in cardiac computed tomography (CT) using a prospectively triggered mode compared with a retrospective ECG-gated helical mode. METHODS:Absorbed organ doses in cardiac 64-row multidetector CT were quantified using an anthropomorphic male Alderson phantom with 74 thermolumi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1767-x
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:To retrospectively determine incidence of early arterial blood flow stasis and its influencing factors during resin-based radioembolization (RE) of liver tumours. METHODS:Data of patients undergoing resin-based RE from 06/2006-12/2013 were reviewed. Second RE procedures of the same liver lobe were excluded....
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-4076-6
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:Left ventricular mass (LVM) at cardiac magnetic resonance imaging (CMR) is a frequent end point in clinical trials in nephrology. Trial participants with end stage renal disease (ESRD) may have a greater frequency of incidental findings (IF). We retrospectively investigated prevalence of IF in previous resea...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4288-4
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:Core biopsy underestimates invasion in more than 20% of patients with preoperatively diagnosed ductal carcinoma in situ (DCIS) without evidence of invasion (pure DCIS). The aim of the current study was to evaluate the efficacy of preoperative magnetic resonance imaging (MRI) to discriminate between patients ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2394-5
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the safety and efficacy of iopentol 350 mg I/ml (Imagopaque/Ivépaque, Nycomed Imaging AS, Oslo, Norway), a monomeric non-ionic contrast medium for computed tomography, in a large population. To identify predictive factors for patient safety. MATERIALS AND METHODS:One thousand eight hundred and t...
journal_title:European radiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/pl00006874
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:To develop and validate a volume-based, quantitative imaging marker by integrating multi-parametric MR images for predicting glioblastoma survival, and to investigate its relationship and synergy with molecular characteristics. METHODS:We retrospectively analysed 108 patients with primary glioblastoma. The d...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4751-x
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:We aimed to assess the diagnostic performance of a combined protocol with coronary computed tomography angiography (CCTA) and stress CT perfusion imaging (CTP) in heart transplant patients for comprehensive morphological and functional imaging. METHODS:In this prospective study, 13 patients undergoing routi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5436-9
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:To investigate the morphological classification of intraductal papillary neoplasm of the bile duct (IPNB), as well as morphological differences between IPNB without mucin secretion (IPNB-NM) and IPNB with mucin secretion (IPMN-B). METHODS:Eighty-one patients with IPNB were retrospectively analysed. Imaging ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5123-2
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:To investigate the added diagnostic value of arterial spin labelling (ASL) and diffusion tensor imaging (DTI) to structural MRI for computer-aided classification of Alzheimer's disease (AD), frontotemporal dementia (FTD), and controls. METHODS:This retrospective study used MRI data from 24 early-onset AD an...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4691-x
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:Magnetic resonance imaging (MRI) acquired on equipment capable of simultaneous MRI and positron emission tomography (PET) could potentially provide the gold standard method for motion correction of PET. To assess the latter, in this study we compared fast 2D and 3D MRI of the torso and used deformation param...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2274-4
更新日期:2012-02-01 00:00:00
abstract::The original version of this article, published on 12 August 2019, unfortunately contained a mistake. The funding note was incorrect; the correct funding note is given below. ...
journal_title:European radiology
pub_type: 已发布勘误
doi:10.1007/s00330-020-06818-5
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the performance of radiomic features extracted from high-resolution computed tomography (HRCT) for the differentiation between cholesteatoma and middle ear inflammation (MEI), and to investigate the impact of post-reconstruction harmonization and data resampling. METHODS:One hundred patients wer...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07564-4
更新日期:2020-12-04 00:00:00
abstract:OBJECTIVES:This study evaluated the performance of a novel automated software tool for epicardial fat volume (EFV) quantification compared to a standard manual technique at coronary CT angiography (cCTA). METHODS:cCTA data sets of 70 patients (58.6 ± 12.9 years, 33 men) were retrospectively analysed using two differen...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-3052-2
更新日期:2014-02-01 00:00:00
abstract::In acute nonvariceal gastrointestinal (GI) bleeding, immediate arteriographic haemostasis is presently assumed to be a therapeutic advantage. This study assesses whether the risk of a delayed haemostasis, caused by arteriographic findings precluding embolization, might influence patient outcome. We performed a 5.5-yea...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-1882-z
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVES:To assess the prognostic value of pre-therapeutic computed tomography (CT) attenuation of liver metastases for overall survival (OS) in metastatic colorectal cancer (mCRC). METHODS:In the open-label, randomised, prospective phase-III FIRE-3 trial, patients with histologically confirmed mCRC received fluorou...
journal_title:European radiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00330-018-5454-7
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:To evaluate percutaneous computed tomography (CT)-guided intracystic and intra-articular steroid injections for the treatment of lumbar facet joint cyst causing radicular pain. METHODS:A single-centre prospective study involving 120 consecutive patients with symptomatic lumbar facet joint cyst-induced radicu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2533-z
更新日期:2012-12-01 00:00:00
abstract::The aim of this study was to evaluate the feasibility of endoluminal stent-graft placement in an angiographic suite for the treatment of emergent type-B aortic dissections and ruptured thoracic aortal aneurysms. Twenty-six patients with either urgent type-B dissection (n=8) or aneurysms (n=18) of the descending thorac...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-1921-9
更新日期:2003-10-01 00:00:00
abstract::Several studies have shown that the thickness of tongue carcinoma is related to prognosis and to the likelihood of cervical node metastases. We investigated whether preoperative estimates of tumor thickness and volume, as determined from magnetic resonance imaging (MRI), correlated with histologic thickness and might ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0263-9
更新日期:2006-10-01 00:00:00
abstract::A 26-year-old woman presented with absence of the left lung. A diagnosis of pulmonary aplasia (main bronchus ending in a blind pouch) was established by bronchoscopy. Although a CT scan and MR imaging suggested the correct diagnosis, MR angiography enabled optimal demonstration of the vascular changes due to the anoma...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/BF00619968
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:To investigate the intra- and inter-observer reliability and agreement between gray-scale and Doppler ultrasound (US) and contrast-enhanced ultrasound (CEUS) in measuring ablated volume (Va) after radiofrequency ablation (RFA) for benign thyroid nodules. METHODS:A total of 173 patients with 190 benign thyroi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07398-0
更新日期:2020-10-31 00:00:00
abstract:OBJECTIVES:To identify the relationship between human epidermal growth factor receptor 2 (HER2) status and cone-beam breast CT (CBBCT) characteristics in surgically resected breast cancer. METHODS:Preoperative CBBCT of patients with BI-RADS 4 or 5 lesions identified on mammography or ultrasound and dense or very dense...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06587-w
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:To clarify the changes in organic anion-transporting polypeptide 8 (OATP8) expression and enhancement ratio on gadoxetic acid-enhanced MR imaging in hepatocellular nodules during multistep hepatocarcinogenesis. METHODS:In imaging analysis, we focused on 71 surgically resected hepatocellular carcinomas (well...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2165-8
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:Radiographs are often performed to assess pelvic and hip parameters, but results depend upon correct pelvis positioning. Three-dimensional (3D) reconstruction from biplanar-radiographs should provide parameters that are less sensitive to pelvic orientation, but this remained to be evaluated. METHODS:Compute...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4452-x
更新日期:2017-03-01 00:00:00
abstract::To assess the practical feasibility and effectiveness of real-time magnetic resonance (MR) temperature monitoring for the radiofrequency (RF) ablation of liver tumours in a clinical setting, nine patients (aged 49-87 years, five men and four women) with one malignant tumour (14-50 mm, eight hepatocellular carcinomas a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1532-1
更新日期:2010-01-01 00:00:00
abstract::We report the case of a 1.5-year-old girl with transient protein-losing gastropathy with hypertrophic gastric folds (PLGH). The diagnosis of PLGH was made by abdominal ultrasound (US) and not by an upper gastrointestinal (UGI) study as reported in many previous publications. Real-time compound ultrasound imaging showe...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-2071-9
更新日期:2003-12-01 00:00:00
abstract::The aim of this study was to compare renal function between patients with renal angiography and patients with renal angiography and angioplasty (AP) for renal artery stenosis (RAS). Forty-seven patients with suspected RAS were prospectively investigated by digital subtraction angiography (DSA) using non-ionic low osmo...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300101075
更新日期:2002-04-01 00:00:00
abstract::N-acetylaspartate/creatine (NAA/Cr) ratios, assessed with proton magnetic resonance spectroscopy, are increasingly used as a surrogate marker for axonal dysfunction and degeneration in multiple sclerosis (MS). The purpose of this study was to test short-time reproducibility of NAA/Cr ratios in patients with clinically...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-0925-x
更新日期:2008-08-01 00:00:00
abstract::Intussusception represents the most common abdominal emergency in infancy. The classical clinical triad, consisting of abdominal colics, red jelly stools and a palpable mass, is only present in approximately 50% of cases, 20% of patients are symptom free at clinical presentation. Primary imaging modality of choice is ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-003-2033-2
更新日期:2004-03-01 00:00:00