Isoflurane and pentobarbital reduce the frequency of transient ischemic depolarizations during focal ischemia in rats.

abstract：:We compared in a prospective, randomized, double-blinded study the analgesic efficacy of three drugs in 120 ASA I and II patients scheduled to undergo ambulatory hand surgery with IV regional anesthesia. At discharge, oral analgesic tablets were prescribed as follows: tramadol 100 mg every 6 h, metamizol 1 g every 6 h...

journal_title：Anesthesia and analgesia

authors： Rawal N,Allvin R,Amilon A,Ohlsson T,Hallén J

更新日期：2001-02-01 00:00:00

abstract：UNLABELLED:We investigated halothane's effects on the function of L-type Ca2+ channels in a human neuronal cell line, SH-SY5Y, by using the cell-attached patch voltage clamp configuration and Ba2+ as the charge carrier. In multiple-channel patches, halothane decreased the peak and persistent Ba2+ currents, accelerated ...

journal_title：Anesthesia and analgesia

authors： Nikonorov IM,Blanck TJ,Recio-Pinto E

更新日期：1998-04-01 00:00:00

abstract：:Clonidine in spinal and epidural blocks prolongs anesthesia, but can cause hypotension and bradycardia. The aim of our study was to compare hemodynamic and analgesic effects of spinal versus epidural clonidine alone and after repetitive dosing. In a prospective, randomized, double-blind study, we evaluated 40 patients...

journal_title：Anesthesia and analgesia

authors： Klimscha W,Chiari A,Krafft P,Plattner O,Taslimi R,Mayer N,Weinstabl C,Schneider B,Zimpfer M

更新日期：1995-02-01 00:00:00

abstract：:In a randomized, double-blind, placebo-controlled trial, we evaluated the use of preoperative local anesthesia with regard to postoperative pain. Before surgery in 66 patients scheduled for cholecystectomy, the abdominal wall along the proposed line of incision was infiltrated with 70 mL of 0.25% ropivacaine, 70 mL of...

journal_title：Anesthesia and analgesia

authors： Johansson B,Glise H,Hallerbäck B,Dalman P,Kristoffersson A

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The etiology of postoperative cognitive decline (POCD) remains to be determined. Anesthetic isoflurane, but not desflurane, may induce neurotoxicity. However, the functional consequences of these effects have not been assessed. We therefore performed a pilot study to determine the effects of isoflurane and d...

journal_title：Anesthesia and analgesia

authors： Zhang B,Tian M,Zhen Y,Yue Y,Sherman J,Zheng H,Li S,Tanzi RE,Marcantonio ER,Xie Z

更新日期：2012-02-01 00:00:00

abstract：UNLABELLED:Because inhibition of voltage-dependent Ca(2+) channels can be a mechanism underlying general anesthesia, we examined sensitivities to propofol and halothane in mice lacking the R-type (Ca(v)2.3) channel widely expressed in neurons. Sleep time after propofol injection (26 mg/kg IV) and halothane MAC(RR) and ...

journal_title：Anesthesia and analgesia

authors： Takei T,Saegusa H,Zong S,Murakoshi T,Makita K,Tanabe T

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Although invasive monitoring is the standard method for intracranial pressure (ICP) measurement, it is not without potential for serious complications. Noninvasive methods have been proposed as alternatives to invasive ICP monitoring. The study aimed to investigate the diagnostic accuracy of the currently av...

journal_title：Anesthesia and analgesia

authors： Sallam A,Abdelaal Ahmed Mahmoud M Alkhatip A,Kamel MG,Hamza MK,Yassin HM,Hosny H,Younis MI,Ramadan E,Algameel HZ,Abdelhaq M,Abdelkader M,Mills KE,Mohamed H

更新日期：2020-09-24 00:00:00

abstract：:Alfentanil, a short-acting lipophilic opioid, is used for labor analgesia and cesarean section and may cause neonatal depression. However, direct placental alfentanil transfer has not been studied. We measured placental alfentanil transfer and uptake during in vitro perfusion. Placenta lobules from healthy parturients...

journal_title：Anesthesia and analgesia

authors： Zakowski MI,Ham AA,Grant GJ

更新日期：1994-12-01 00:00:00

abstract：UNLABELLED:We investigated the effect of IV droperidol on the bispectral index (BIS) in conscious and propofol-sedated patients during spinal anesthesia. Thirty minutes after the induction of spinal anesthesia, 20 patients were given 2 mg of droperidol IV without administration of other sedatives (conscious group). Ano...

journal_title：Anesthesia and analgesia

authors： Nakayama M,Kanaya N,Ichinose H,Yamamoto S,Namiki A

更新日期：2003-03-01 00:00:00

abstract：UNLABELLED:The aim of this study was to examine the antiallodynic and antinociceptive effects of subcutaneously administered physostigmine (50, 100, 200 micrograms/kg), compared with morphine (2.5, 5, 10 mg/kg) and NaCl after spinal nerve ligation in rats. The following stimuli were used: acetone (cold allodynia), von ...

journal_title：Anesthesia and analgesia

authors： Pöyhiä R,Xu M,Kontinen VK,Paananen S,Kalso E

更新日期：1999-08-01 00:00:00

abstract：:Animal studies suggest that increased circulating estrogen and progesterone, and activation of the endorphin system cause prenancy-induced antinociceptive effects. Human studies have provided inconsistent results and have often lacked a nonpregnant control group. In this study, we compared sensitivity to experimental ...

journal_title：Anesthesia and analgesia

authors： Carvalho B,Angst MS,Fuller AJ,Lin E,Mathusamy AD,Riley ET

更新日期：2006-11-01 00:00:00

abstract：:The purpose of this study was to compare the psychological effects of ketamine and thiopental anesthesia. In a double-blind comparison, 20 normal female volunteers were given 2.5 mg/kg ketamine intravenously and 20 were given 5.0 mg/kg thiopental intravenously. Subjects were assessed with a variety of objective and su...

journal_title：Anesthesia and analgesia

authors： Moretti RJ,Hassan SZ,Goodman LI,Meltzer HY

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Intraoperative hypoglycemia can result in devastating neurologic injury if not promptly diagnosed and treated. Few studies have defined risk factors for intraoperative hypoglycemia. The authors sought to characterize children with intraoperative hypoglycemia and determine independent risk factors in a multic...

journal_title：Anesthesia and analgesia

authors： Riegger LQ,Leis AM,Golmirzaie KH,Malviya S

更新日期：2020-06-25 00:00:00

abstract：:Spontaneous ventilation may offer advantages over controlled mechanical ventilation (CMV), but increase in work of breathing may diminish its usefulness. During general anesthesia, respiratory depression and increased work of breathing often preclude spontaneous ventilation, and patients then receive CMV. We compared ...

journal_title：Anesthesia and analgesia

authors： Christie JM,Smith RA

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Xenon has many characteristics that make it very attractive as an anesthetic and therapeutic drug. Unfortunately, the supply of xenon is fixed, and therefore reclamation and recovery from even the most efficient breathing circuits is desirable. We built and evaluated a cryogenic device to recover xenon from ...

journal_title：Anesthesia and analgesia

authors： Dingley J,Mason RS

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Propofol can be measured in exhaled gas. Exhaled and plasma propofol concentrations correlate well, but the relationship with tissue concentrations remains unknown. We thus evaluated the relationship between exhaled, plasma, and various tissue propofol concentrations. Because the drug acts in the brain, we f...

journal_title：Anesthesia and analgesia

authors： Müller-Wirtz LM,Maurer F,Brausch T,Kiefer D,Floss M,Doneit J,Volk T,Sessler DI,Fink T,Lehr T,Kreuer S

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:IV lipid emulsion has demonstrated to be effective therapy for bupivacaine-induced cardiotoxicity. However, the role of epinephrine when coadministered with lipid emulsion in toxin-induced cardiac arrest is unclear. We postulated superior resuscitation outcome in the absence of epinephrine in a rabbit model ...

journal_title：Anesthesia and analgesia

authors： Harvey M,Cave G,Prince G,Lahner D

更新日期：2010-09-01 00:00:00

abstract：:Combinations of nonsteroidal antiinflammatory drugs (NSAIDs) and opioids are widespread in the management of pain, allowing better analgesia with reduced side effects. Cannabinoids are promising analgesic drugs that have pharmacological properties similar to those of opioids. However, the beneficial effects of cannabi...

journal_title：Anesthesia and analgesia

authors： Ulugöl A,Ozyigit F,Yesilyurt O,Dogrul A

更新日期：2006-02-01 00:00:00

abstract：UNLABELLED:We studied 160 ASA I or II patients undergoing elective otolaryngologic surgery in order to compare the anxiolytic effects of a novel 5-hydroxytryptamine-1A agonist, tandospirone, with diazepam. To monitor preoperative anxiety, the following variables were used: systolic and diastolic arterial pressure, hear...

journal_title：Anesthesia and analgesia

authors： Oshima T,Kasuya Y,Terazawa E,Nagase K,Saitoh Y,Dohi S

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Both femoral and obturator nerve blocks have been suggested to be useful in relieving pain after total knee arthroplasty (TKA). We sought to compare their efficacy. METHODS:Sixty patients undergoing elective unilateral TKA under spinal anesthesia received in a randomized, double-blind manner a femoral, obtu...

journal_title：Anesthesia and analgesia

authors： Kardash K,Hickey D,Tessler MJ,Payne S,Zukor D,Velly AM

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Atelectasis occurs regularly after induction of general anesthesia, persists postoperatively, and may contribute to significant postoperative morbidity and additional health care costs. Laparoscopic surgery has been reported to be associated with an increased incidence of postoperative atelectasis. It has be...

journal_title：Anesthesia and analgesia

authors： Talab HF,Zabani IA,Abdelrahman HS,Bukhari WL,Mamoun I,Ashour MA,Sadeq BB,El Sayed SI

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Anesthesia induction in children is frequently achieved by inhalation of nitrous oxide and sevoflurane. Pediatric anesthesiologists commonly use distraction techniques such as humor or nonprocedural talk to reduce anxiety and facilitate a smooth transition at this critical phase. There is a large body of suc...

journal_title：Anesthesia and analgesia

authors： Mifflin KA,Hackmann T,Chorney JM

更新日期：2012-11-01 00:00:00

abstract：:Catecholamine and serotonin concentrations in the cord, medulla, and hypothalamus were measured in rats after saline, after sufentanil sufficient to reduce the minimum alveolar concentration (MAC) of halothane by 30% or less, or after sufentanil sufficient to reduce the MAC of halothane by 80% or more. In the cord, hi...

journal_title：Anesthesia and analgesia

authors： Althaus JS,Miller ED Jr,Moscicki JC,Hecker BR,DiFazio CA

更新日期：1985-09-01 00:00:00

abstract：:The extent of sensory and motor blockades was examined in 195 patients 5 and 20 min after four different techniques of brachial plexus block using 50 ml of 0.5% bupivacaine. The interscalene technique of Winnie (N = 50) resulted in a preferential blockade of the caudad portions of the cervical plexus and the cephalad ...

journal_title：Anesthesia and analgesia

authors： Lanz E,Theiss D,Jankovic D

更新日期：1983-01-01 00:00:00

abstract：:Continuous peripheral nerve blockade is often used for the management of postoperative pain, even in ambulatory patients. The reported incidence of infectious complications after continuous nerve blockade is low. We report a case of Staphylococcus aureus sepsis after total shoulder arthroplasty in a patient who presen...

journal_title：Anesthesia and analgesia

authors： Clendenen SR,Robards CB,Wang RD,Greengrass RA

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:In this randomized study, we compared intrathecal (i.t.) morphine with or without clonidine and i.v. postoperative patient-controlled analgesia (PCA) morphine for analgesia after radical retropubic prostatectomy. METHODS:Fifty patients were randomly divided into three groups. They were allocated to receive ...

journal_title：Anesthesia and analgesia

authors： Andrieu G,Roth B,Ousmane L,Castaner M,Petillot P,Vallet B,Villers A,Lebuffe G

更新日期：2009-06-01 00:00:00

abstract：:The role of succinylcholine in the precipitation of malignant hyperthermia (MH) necessitates the testing of new neuromuscular relaxants for their ability to trigger MH in MH-susceptible swine before general human use. We tested doxacurium and mivacurium, two new nondepolarizing bis-benzylisoquinolinium neuromuscular r...

journal_title：Anesthesia and analgesia

authors： Sufit RL,Kreul JF,Bellay YM,Helmer P,Brunson DB,Will J

更新日期：1990-09-01 00:00:00

abstract：:The low solubility of desflurane contributes to rapid emergence after outpatient anesthesia. Compared with isoflurane, recovery times to eye opening, response to verbal commands, and orientation to person, place, and time have been significantly shorter. Even when compared with the rapid, short-acting intravenous anes...

journal_title：Anesthesia and analgesia

authors： White PF

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Surgical site infiltration with local anesthetic reduces analgesic requests in various types of surgeries. Because thyroid surgery may induce severe postoperative pain, we tested the hypothesis that ropivacaine surgical site infiltration would significantly decrease postoperative administration of morphine i...

journal_title：Anesthesia and analgesia

authors： Miu M,Royer C,Gaillat C,Schaup B,Menegaux F,Langeron O,Riou B,Aubrun F

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Conventional concept suggests that infused crystalloid fluid is first distributed in the plasma volume and then, since the capillary permeability for fluid is very high, almost instantly equilibrates with the extracellular fluid space. We challenge whether this view is consistent with findings based on volum...

journal_title：Anesthesia and analgesia

authors： Svensen CH,Rodhe PM,Olsson J,Børsheim E,Aarsland A,Hahn RG

更新日期：2009-01-01 00:00:00