Successful treatment of acute subretinal hemorrhage in age-related macular degeneration by combined intravitreal injection of recombinant tissue plasminogen activator and gas.

abstract：:Recently, high levels of neurotrophic factors have been found in bronchial asthma; these factors include nerve growth factor, brain-derived neurotrophic factor, and leukemia inhibitory factor, among others. Neurotrophic factors are first synthesized in bronchial epithelial cells, immune cells, and other cells in the a...

journal_title：Advances in therapy

authors： Feng JT,Hu CP,Li XZ

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:Partial nephrectomy (PN) has evolved into the surgical standard of care for localized renal lesions. Hemostatic agents (HA) support the surgeon in achieving local hemostasis during PN. We previously reported initial results with the HA Hemopatch® in PN. We now report our experiences with Hemopatch® in a la...

journal_title：Advances in therapy

authors： Hupe MC,Büttner M,Tabrizi PF,Merseburger AS,Kuczyk MA,Imkamp F

更新日期：2020-12-04 00:00:00

abstract：INTRODUCTION:Advances in cystic fibrosis (CF) therapy have resulted in improved survival and increasing treatment burden and costs. The economic impact of current treatment strategies for CF is poorly defined. METHODS:The authors prospectively assessed direct medical costs (including hospitalizations, outpatient inter...

journal_title：Advances in therapy

authors： Colombo C,Daccò V,Alicandro G,Loi S,Mazzi S,Lucioni C,Ravasio R

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:Advanced renal cell carcinoma (RCC) shows a propensity for extending into the tributaries of the renal veins, which poses a notable surgical challenge. In this study we addressed the question as to whether patients with RCC and vein involvement can be identified as having a significant risk of immediate de...

journal_title：Advances in therapy

authors： Akkoyun M,Merseburger AS,Kramer MW,Herrmann TR,Kuczyk MA,von Klot CA

更新日期：2015-08-01 00:00:00

abstract：INTRODUCTION:Respiratory tract infections are common, and these infections occur frequently in children, susceptible adults, and older persons. The risk for recurrences and complications relates not only to the presence of viruses but also to immune function. Therefore, modulation of the immune system and antiviral int...

journal_title：Advances in therapy

authors： Schapowal A,Klein P,Johnston SL

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:Nivolumab has been approved in patients with melanoma with lymph node involvement or metastatic disease who have undergone complete resection, in the adjuvant setting. A pivotal trial compared nivolumab with ipilimumab; however, no head-to-head trial exists comparing nivolumab to observation, a common comp...

journal_title：Advances in therapy

authors： Freeman M,Betts KA,Jiang S,Du EX,Gupte-Singh K,Lu Y,Rao S,Shoushtari AN

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:This retrospective study used data from a primary care database to compare two insulin products in routine clinical practice for the treatment of type 2 diabetes in the UK. PATIENTS AND METHODS:Records were analyzed for patients with type 2 diabetes who had been initiated on biphasic insulin aspart 30 (BI...

journal_title：Advances in therapy

authors： Fakhoury WK,Richter H,Christensen TE

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:Spinal muscular atrophy (SMA) is a neurodegenerative disease of the motor neurons that results in progressive muscle weakness. It is also the leading hereditary cause of infant mortality. Homozygous loss of the survival motor neuron (SMN1) gene causes SMA, and the number of copies of the SMN2 gene modulate...

journal_title：Advances in therapy

authors： Dayangaç-Erden D,Topaloğlu H,Erdem-Yurter H

更新日期：2008-03-01 00:00:00

abstract：:Bacterial translocation is the passage of bacteria or endotoxins from the gastrointestinal tract to extraintestinal sites, such as mesenteric lymph nodes, liver, spleen, and bloodstream. In this study, the investigators examined the effects of various enteral nutrients on bacterial translocation and intestinal morphol...

journal_title：Advances in therapy

authors： Aydogan A,Kismet K,Kilicoglu B,Erel S,Ozcan AH,Gollu A,Yildiz E,Akkus MA

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:To compare the efficacy and safety of combined cataract extraction and either excisional goniotomy performed with the Kahook Dual Blade (KDB; phaco-KDB group) or single iStent trabecular bypass implantation (phaco-iStent group) in eyes with mild to moderate glaucoma and visually significant cataract. METHODS:T...

journal_title：Advances in therapy

authors： ElMallah MK,Seibold LK,Kahook MY,Williamson BK,Singh IP,Dorairaj SK,KDB Goniotomy Study Group.

更新日期：2019-09-01 00:00:00

abstract：:Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to...

journal_title：Advances in therapy

authors： Coca-Pelaz A,Barnes L,Rinaldo A,Cardesa A,Shah JP,Rodrigo JP,Suárez C,Eloy JA,Bishop JA,Devaney KO,Thompson LD,Wenig BM,Strojan P,Hamoir M,Bradley PJ,Gnepp DR,Silver CE,Slootweg PJ,Triantafyllou A,Vander Poorten V,

更新日期：2016-04-01 00:00:00

abstract：:In the past 15 years, improvements in the treatment of HIV infection have dramatically reduced morbidity and mortality. Nucleoside reverse transcriptase inhibitors are the backbone of combination antiretroviral therapy for the treatment of HIV. One of the recommended and commonly used therapies in this class is the on...

journal_title：Advances in therapy

authors： Achenbach CJ,Scarsi KK,Murphy RL

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:In FRESCO (Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients) trial, fruquintinib demonstrated a statistically significant and clinically meaningful overall survival benefit in Chinese patients with metastatic colorectal cancer (mCRC). However, its safety profile, including adverse eve...

journal_title：Advances in therapy

authors： Li J,Guo W,Bai Y,Deng Y,Yang L,Chen Z,Zhong H,Xu R,Pan H,Shu Y,Yuan Y,Zhou J,Xu N,Liu T,Ma D,Wu C,Cheng Y,Xu J,Chen D,Li W,Sun S,Yu Z,Cao P,Shen L,Chen H,Wang S,Wang H,Fan S,Guo X,Wang N,Han R

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:Pigmented villonodular synovitis (PVNS), also known as giant-cell tumour of the tendon sheath (GCTT), is a rare, benign proliferative tumour affecting the inner lining of synovial joints and tendon sheets. Information on treatment needs of PVNS patients to inform drug development is currently scarce. We co...

journal_title：Advances in therapy

authors： Cook NS,Landskroner K,Shah B,Walda S,Weiss O,Pallapotu V

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Recent research has suggested that serum tumor markers can give valuable prognostic information in gastric cancer. In this study, we examined the relationship between preoperative serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, CA 72-4, and alfa fetoprotein (AFP) levels on clinicopath...

journal_title：Advances in therapy

authors： Ucar E,Semerci E,Ustun H,Yetim T,Huzmeli C,Gullu M

更新日期：2008-10-01 00:00:00

abstract：:Hypertension is recognized as a major risk factor for cardiovascular and renal diseases and represents the leading cause of mortality worldwide. In spite of proven benefits of hypertension treatment, blood pressure control rates are poor, even in high-income countries with virtually full-access to therapies. Nearly 75...

journal_title：Advances in therapy

authors： Gorostidi M,de la Sierra A

更新日期：2013-04-01 00:00:00

abstract：:The aims of this study were to determine whether the nursing costs of functional disability could be assessed retrospectively and, if so, whether this method was sensitive enough to show the influence of a treatment on economic costs. Four studies were available for this purpose: three randomized, double-blind, place...

journal_title：Advances in therapy

authors： Vlietinck R,Van Loon H,Van de Broele H,Tormans G

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is a serious health concern. Repurposing of existing drugs indicated for other conditions seems to be the first choice for immediate therapeutic management. The quality of early evidence favoring the different treatment options needs t...

journal_title：Advances in therapy

authors： Subramanian K,Nalli A,Senthil V,Jain S,Nayak A,Bhat A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Studies assessing the effect of high dose tigecycline on severe infections are limited and remain controversial. OBJECTIVES:To assess systematically the effectiveness and safety of high dose tigecycline in the treatment of severe infections. METHODS:Pubmed, Web of Science, Embase, MEDLINE, Cochrane Library...

journal_title：Advances in therapy

authors： Zha L,Pan L,Guo J,French N,Villanueva EV,Tefsen B

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:A recent successful clinical trial demonstrated that a less invasive cell-injection procedure is a viable medical modality for treating corneal endothelial dystrophy. This medical advance still relies on human corneal endothelial cell (HCEC) sources derived from rare cornea donations. The progenitor of the corn...

journal_title：Advances in therapy

authors： Meir YJ,Chen HC,Chen CC,Ma HD

更新日期：2020-03-01 00:00:00

abstract：:Liver transplantation has become a highly standardized, acceptable option for selected patients with end-stage liver disease and/or hepatocellular carcinoma in the setting of cirrhosis. Both conditions are associated with loss of skeletal muscle mass (sarcopenia) and physical deconditioning. Both conditions result in ...

journal_title：Advances in therapy

authors： Beekman L,Berzigotti A,Banz V

更新日期：2018-11-01 00:00:00

abstract：:Coronary heart disease is the major cause of morbidity and mortality in industrialized countries, and its prevalence is predicted to grow as the population ages. Current drugs for chronic stable angina (such as beta-blockers, calcium-channel blockers, long- and short-acting nitrates, and potassium-channel activators) ...

journal_title：Advances in therapy

authors： Prasad UK,Gray D,Purcell H

更新日期：2009-02-01 00:00:00

abstract：:The prognosis for patients with rheumatoid arthritis or spondyloarthritides has improved dramatically due to earlier diagnosis, recognition of the need to treat early with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), alone or in combinations, the establishment of treatment targets, and the ...

journal_title：Advances in therapy

authors： Govoni M,Bortoluzzi A,Lo Monaco A,Adami S,Addimanda O,Caimmi C,De Vita S,Ferri C,Manfredi A,Orsolini G,Possemato N,Quartuccio L,Salvarani C,Zabotti A,Rossini M

更新日期：2014-08-01 00:00:00

abstract：:Despite the results from clinical trials in patients with hypertension and the development of a long list of guidelines for the management of hypertension, many physicians and other healthcare professionals still manage hypertension using approaches that clearly diverge at least partially from the recommendations of t...

journal_title：Advances in therapy

authors： Malacco E,Ferri C,Grandi AM,Kilama MO,Soglian AG,Vigna L

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:Little has been published on respiratory syncytial virus (RSV) among Medicare patients at high risk (HR) of RSV complications due to age or comorbidity. METHODS:Adult patients (at least 18 years of age) with at least 1 diagnostic code for RSV were identified using the 5% US Medicare database from 2011 thr...

journal_title：Advances in therapy

authors： Wyffels V,Kariburyo F,Gavart S,Fleischhackl R,Yuce H

更新日期：2020-03-01 00:00:00

abstract：:This prospective study was performed to determine whether gentamicin can be prescribed routinely to patients with spinal cord injury undergoing urologic procedures, or whether antibiotic therapy must be selected on the basis of recent urine microbiologic test results. Between January 2004 and June 2005, procedures wer...

journal_title：Advances in therapy

authors： Vaidyanathan S,Soni BM

更新日期：2006-01-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which can induce multisystem disease. Human angiotensin-converting enzyme 2 (ACE2) widely expressing in arterial and venous endothelial cells and arterial smooth muscle cells has been identified as a functional rec...

journal_title：Advances in therapy

authors： Wang J,Saguner AM,An J,Ning Y,Yan Y,Li G

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:This Phase 2 clinical trial assessed the efficacy and safety of the novel antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and symptoms. METHODS:In a single-center, randomized, double-masked, placebo-controlled, 29-day study, 91 subjects with mild to moderate dry eye instilled...

journal_title：Advances in therapy

authors： Petrov A,Perekhvatova N,Skulachev M,Stein L,Ousler G

更新日期：2016-01-01 00:00:00

abstract：:This 4-week double-blind, placebo-controlled study assessed the efficacy of impulse magnetic-field therapy for insomnia. One hundred one patients were randomly assigned to either active treatment (n = 50) or placebo (n = 51) and allocated to one of three diagnostic groups: (1) sleep latency; (2) interrupted sleep; or ...

journal_title：Advances in therapy

authors： Pelka RB,Jaenicke C,Gruenwald J

更新日期：2001-07-01 00:00:00

abstract：INTRODUCTION:Most cases of small cell lung cancer (SCLC) are diagnosed at an advanced stage. The objective of this study was to investigate patient characteristics, survival, chemotherapy treatments, and health care use after a diagnosis of advanced SCLC in subjects enrolled in a health system network. METHODS:This wa...

journal_title：Advances in therapy

authors： He J,Shao C,Hui SL,Zhang Z,Baker J,Dexter PR,Kachroo S,Jin F

更新日期：2020-01-01 00:00:00