Recurrent thrombo-embolic episodes: the association of cholangiocarcinoma with antiphospholipid syndrome.

abstract：:Digital clubbing has been a well recognised feature of several distinct clinical conditions, including respiratory, cardiac, and gastrointestinal diseases since the Hippocratic era. However, clubbing associated with Behçet's disease has not been reported before. We describe a case of clubbing in a young man with Behçe...

journal_title：Postgraduate medical journal

authors： Benekli M,Güllü IH

更新日期：1997-09-01 00:00:00

abstract：:Prospective measurements of serum thyrotrophin and thyroxine concentrations were made in six patients with primary hypothyroidism treated consecutively with an incremental regimen of oral thyroxine. A fall in thyrotrophin occurred over several months, accompanied by a concurrent slow rise in serum thyroxine. Those pat...

journal_title：Postgraduate medical journal

authors： Ghose RR,Upadhyay HP

更新日期：1986-01-01 00:00:00

abstract：:The interpretation of gastrin release is confused because of variation in the technique of the radioimmuoassay of gastrin, the lack of a standard stimulus for the release of gastrin and diversity in the method used to express the results. These problems have been analysed (a) by examining the cross-reactivity of three...

journal_title：Postgraduate medical journal

authors： Russel RC,Bloom SR,Fielding LP,Bryant MG

更新日期：1976-10-01 00:00:00

abstract：:The 1994 NACT Wyeth-Ayerst Travelling Fellowship provided the opportunity to compare the education and welfare of pre-registration house officers in the UK with their nearest counterpart in the US residency system. Investment in all aspects of learning was impressive, as was the retention of the central role of the pa...

journal_title：Postgraduate medical journal

authors： Salter R

更新日期：1995-05-01 00:00:00

abstract：:Six cases of tuberculous meningitis, all occurring in patients over the age of 65, are described. All patients presented with an acute illness, primarily with a confusional state. Headache was a symptom in only two patients and the cases were not confined to ethnic minority groups. The mortality was 50%. ...

journal_title：Postgraduate medical journal

authors： Dixon PE,Hoey C,Cayley AC

更新日期：1984-09-01 00:00:00

abstract：:The mechanisms of the antinociceptive action of flupirtine, a novel non-opioid analgesic, were investigated in animals. It was found that this effect could be abolished by pre-treatment with reserpine. Furthermore, it could be dose-dependently antagonized by yohimbine and changes in the EEG of the rat observed after a...

journal_title：Postgraduate medical journal

authors： Szelenyi I,Nickel B

更新日期：1987-01-01 00:00:00

abstract：:Colonic strictures are very common and are a frequent finding on double contrast barium examination; they very often reflect the presence of malignancy, diverticular disease, ischaemia, inflammatory bowel disease, and rarely mycobacterial disease. A case of mycobacterial disease mimicking malignancy is presented; this...

journal_title：Postgraduate medical journal

authors： Rees JR,Longstaff A,Rigby HL,Smith DL,Dixon AR

更新日期：2003-12-01 00:00:00

abstract：:Herpes simplex encephalitis may be underdiagnosed in Britain. We report eight patients treated at one hospital over three years. Fever, impaired consciousness or focal neurological signs were seen in all patients at presentation but herpes simplex encephalitis was rarely considered as the initial diagnosis. The electr...

journal_title：Postgraduate medical journal

authors： Gulliford MC,Chandrasekera CP,Cooper RA,Murphy RP

更新日期：1987-12-01 00:00:00

abstract：:A fatal case of occult foramen magnum meningioma is described which presented with features of cervical myelopathy confirmed by cervical myelogram. Surgical decompression led to initial improvement followed by progressive deterioration and death. Postmortem examination revealed a 4 cm diameter foramen magnum meningiom...

journal_title：Postgraduate medical journal

authors： Chakravarty K,Scott DG,Dick D,Visick J

更新日期：1993-09-01 00:00:00

abstract：:Thiazide diuretics used alone to treat hypertension can cause hypokalaemia in a substantial proportion of patients. The possibility exists that any benefit of reducing high blood pressure by such treatment may be offset by an increased mortality due to arrhythmias initiated by hypokalaemia. ...

journal_title：Postgraduate medical journal

authors： Poole-Wilson PA

更新日期：1983-01-01 00:00:00

abstract：:Leg ulcer is a leading cause of morbidity among older subjects, especially women in the Western world. About 400 years BC, Hippocrates wrote, "In case of an ulcer, it is not expedient to stand, especially if the ulcer be situated on the leg". Hippocrates himself had a leg ulcer. The best treatment of any leg ulcer dep...

journal_title：Postgraduate medical journal

authors： Sarkar PK,Ballantyne S

更新日期：2000-11-01 00:00:00

abstract：:The anti-hypertensive effect of 250 mg tienilic acid was comparable to that of 50 mg hydrochlorothiazide. Unlike hydrochlorothiazide, tienilic acid caused a statistically significant decrease in the serum uric acid values. Clinically non-significant rises in blood urea nitrogen and serum creatinine occurred with both ...

journal_title：Postgraduate medical journal

authors： McMahon FG,Ryan JR,Jain AK

更新日期：1979-01-01 00:00:00

abstract：:The acute haemodynamic effects of endralazine, a new hydralazine-like vasodilating agent, were studied in 6 patients with stable angina pectoris and proven coronary artery disease. Twenty minutes after intravenous administration of 5 mg endralazine heart rate and cardiac index increase, while mean arterial blood press...

journal_title：Postgraduate medical journal

authors： van der Wall EE,de Feyter PJ,Res JC,Roos JP,van Engelen CL

更新日期：1983-01-01 00:00:00

abstract：:Gastric cancer is a cause of significant morbidity and mortality. There are several risk factors, with occupation emerging as one of these. There is considerable evidence that occupations in coal and tin mining, metal processing, particularly steel and iron, and rubber manufacturing industries lead to an increased ris...

journal_title：Postgraduate medical journal

authors： Raj A,Mayberry JF,Podas T

更新日期：2003-05-01 00:00:00

abstract：:This is a case report of a 67 year old man who presented with a fluctuating level of consciousness and myoclonic jerks caused in part by hypercalcaemia. The diagnosis of cerebral neoplastic angioendotheleosis was only made later on brain biopsy and is the first report of the occurrence of hypercalcaemia in neoplastic ...

journal_title：Postgraduate medical journal

authors： Wierzbicki AS,Gibbs JM,Lidov HG,Lolin Y,Thomas PK

更新日期：1991-06-01 00:00:00

abstract：:A patient with acute lymphoblastic leukaemia who developed ovarian and uterine leukaemic relapse while in bone marrow remission is described. Pelvic relapse is rarely reported during the clinical course of leukaemia in females. Pelvic ultrasonography, a non-invasive procedure, was of value as an aid in detecting pelvi...

journal_title：Postgraduate medical journal

authors： Cantwell B,Cantwell D,Fennelly JJ

更新日期：1982-11-01 00:00:00

abstract：:The inflammatory neuropathies are a large diverse group of immune-mediated neuropathies that are amenable to treatment and may be reversible. Their accurate diagnosis is essential for informing the patient of the likely course and prognosis of the disease, informing the treating physician of the appropriate therapy an...

journal_title：Postgraduate medical journal

authors： Lunn MP,Willison HJ

更新日期：2009-08-01 00:00:00

abstract：:Two-hundred and nine patients were entered into a prospective, randomized trial in order to determine whether a vertical or transverse abdominal incision is the more satisfactory in producing sound wounds. Ninety-six patients were randomized between paramedian and transverse incisions, and followed up for at least 1 y...

journal_title：Postgraduate medical journal

authors： Ellis H,Coleridge-Smith PD,Joyce AD

更新日期：1984-06-01 00:00:00

abstract：:The effect of graded exercise on the secretion of cortisol, testosterone, prolactin, growth hormone, thyroid stimulating hormone (TSH), luteinizing hormone and follicle stimulating hormone (FSH) is reported. While cortisol, prolactin, growth hormone and testosterone rise during the period of exercise, a rise in lutein...

journal_title：Postgraduate medical journal

authors： Gawel MJ,Park DM,Alaghband-Zadeh J,Rose FC

更新日期：1979-06-01 00:00:00

abstract：:In severe appendicitis, the effect of a single intravenous dose of metronidazole (500 mg) was compared with cefoxitin (1 g). The antibiotics were given by random allocation once the diagnosis had been established at operation. In the metronidazole group, 5 out of 48 patients developed a wound infection whilst in hospi...

journal_title：Postgraduate medical journal

authors： Corder AP,Bates T,Prior JE,Harrison M,Donaldson PJ

更新日期：1983-11-01 00:00:00

abstract：:Focused assessment with sonography in trauma (FAST) is a limited ultrasound scan performed in the emergency department to assess patients admitted with blunt abdominal trauma (BAT). It is normally undertaken by emergency physicians in order to identify the presence of free fluid, which may represent haemoperitoneum. T...

journal_title：Postgraduate medical journal

authors： Smith J

更新日期：2010-05-01 00:00:00

abstract：:A previously healthy 17 year old boy had Staphylococcus aureus endocarditis presenting as acute scrotal pain. There was no trauma or evidence of scrotal or epididymal infection. The pain subsided after therapy for endocarditis was started. ...

journal_title：Postgraduate medical journal

authors： Watanakunakorn C

更新日期：1987-07-01 00:00:00

abstract：:Most vertebral haemangiomas are asymptomatic. A case of spinal reconstruction for symptomatic extraosseous thoracic haemangioma using a titanium cage is reported. Radiographs of the T11 vertebra demonstrated characteristic vertical striations. Magnetic resonance imaging and computed tomography showed spinal cord compr...

journal_title：Postgraduate medical journal

authors： Ogura T,Mori M,Hayashida T,Osawa T,Hase H

更新日期：2002-09-01 00:00:00

abstract：:Weekly low dose methotrexate is an established treatment for rheumatoid arthritis, but its use in elderly people has not been adequately examined. The aim of this study was to evaluate its safety in elderly patients with rheumatoid arthritis. A retrospective review of the clinical records of rheumatoid arthritis patie...

journal_title：Postgraduate medical journal

authors： Hirshberg B,Muszkat M,Schlesinger O,Rubinow A

更新日期：2000-12-01 00:00:00

abstract：:Postgraduate medical education (PME) quality assurance at Health Education England (HEE) currently relies upon survey data. As no one metric can reflect all aspects of training, and each has its limitations, additional metrics should be explored. At HEE (West Midlands), we explored the use of learner outcomes, special...

journal_title：Postgraduate medical journal

authors： Pinnell J,Tranter A,Cooper S,Whallett A

更新日期：2020-11-12 00:00:00

abstract：:Although recognized since the 1930s, slow infections have only recently received considerable attention. There are three types, group A (related to the type C RNA viruses), group B (bizarre agents such as scrapie and kuru) and group C (viruses such as measles which normally produce acute infections but which are behav...

journal_title：Postgraduate medical journal

authors： Sutton RN

更新日期：1979-02-01 00:00:00

abstract：:A 60 year old woman with computed tomographic-verified bilateral thalamic infarction is described. She demonstrated downward gaze paralysis, amnesia and hypersomnolence. On the functional level such tasks as walking and eating were disconcerting. Although there have been only a few reports of the complete triad it may...

journal_title：Postgraduate medical journal

authors： Nagaratnam N,Ghougassian DF,Mugridge V

更新日期：1989-11-01 00:00:00

abstract：:Although primary percutaneous coronary intervention (PCI) in clinical trials has lower rates of reinfarction, stroke and mortality than fibrinolytic therapy, because of system delays in routine practice, field triage and prehospital administration of fibrinolytic therapy may lead to similar clinical outcomes, especial...

journal_title：Postgraduate medical journal

authors： Edmond JJ,Juergens CP,French JK

更新日期：2009-06-01 00:00:00

abstract：:A host/vector system suitable for large-scale production of HBsAg has been constructed and optimized in terms of the expression plasmid and yeast host strain in order to permit fermentation to very high cell densities. The final expression plasmid contains the coding sequence of the major HBsAg protein (P24) flanked b...

journal_title：Postgraduate medical journal

authors： Harford N,Cabezon T,Colau B,Delisse AM,Rutgers T,De Wilde M

更新日期：1987-01-01 00:00:00

abstract：:A 24-year-old man with primary Sjögren's syndrome presented with xerophthalmia, xerostomia, and marked parotid swelling. He had a previous history of selective IgA deficiency and ulcerative colitis treated with sulphasalazine. Immunosuppression and withdrawal of sulphasalazine resulted in rapid resolution of the parot...

journal_title：Postgraduate medical journal

authors： Steuer A,McCrea DJ,Colaco CB

更新日期：1996-08-01 00:00:00