Acyclovir treatment of herpes simplex encephalitis: experience in a district hospital.

abstract：:Osteoporosis is a very common disorder, which results in an increase in fracture risk. The annual cost attributable to hip, vertebral, and wrist fractures in England and Wales is pound 1.7 billion. Significant mortality and morbidity are associated with osteoporotic fractures. The method that is most widely used for t...

journal_title：Postgraduate medical journal

authors： Christodoulou C,Cooper C

更新日期：2003-03-01 00:00:00

abstract：:In a cross-over study, 10 healthy adult volunteers received 1 g cefaclor and 1 g cephalexin orally 1 hour after a standard breakfast. Serum levels of cefaclor rose somewhat faster and were higher than those of cephalexin in the first 60 minutes. At the end of the second hour the serum concentration of cephalexin was 5...

journal_title：Postgraduate medical journal

authors： Simon C,Gatzemeier U

更新日期：1979-01-01 00:00:00

abstract：:Tienilic acid is a diuretic-uricosuric compound whose natriuretic site of action is in the cortical diluting segment of the distal nephron. Oral doses of 250 mg given to normal human volunteers provided peak blood levels of 10--11 micrograms/ml at 3--4 hours after administration. Approximately 40% of the dose was reco...

journal_title：Postgraduate medical journal

authors： Dubb JW,Stote RM,Maass AR,Hwang BV,Familiar RG,Alexander F

更新日期：1979-01-01 00:00:00

abstract：:Both the quality and the quantity of food ingested are relevant to the genesis of risk factors for coronary heart disease and the two are inseparable. Nevertheless they have a major common pathway through hypertension, which may well be the most important consequence of a high-protein, high-carbohydrate, high-fat, hig...

journal_title：Postgraduate medical journal

authors： Brook CG

更新日期：1978-03-01 00:00:00

abstract：:Cough is one of the commonest symptoms of lung disease and is a frequent problem encountered in general practice as well as in hospital practice. A wide range of disease processes may present with cough and definitive treatment depends on making an accurate diagnosis of the cause. A diagnostic work-up for patients wit...

journal_title：Postgraduate medical journal

authors： Chung KF,Lalloo UG

更新日期：1996-10-01 00:00:00

abstract：:The Chancellor of the Exchequer's recent announcements to devolve decision making power from Whitehall to 30 English regions provide a challenge to use devolution to deliver more favourable health outcomes. However evaluation of devolved health models internationally is scarce, because it is rarely considered. Evidenc...

journal_title：Postgraduate medical journal

authors： Doyle Y,Johnstone P

更新日期：2016-05-01 00:00:00

abstract：:An 84 year old woman who was a heavy smoker presented with clinical features suggestive of acute exacerbation of chronic obstructive lung disease complicated by left ventricular failure. She responded poorly to treatment and then the finding of stridor, only when she was in the supine position, led to the diagnosis of...

journal_title：Postgraduate medical journal

authors： Antonios TF,Singer DR,Millard FJ,Wilson AG,MacGregor GA

更新日期：1994-12-01 00:00:00

abstract：:Previous reports have demonstrated that patients with hypertrophic cardiomyopathy (HCM) have prolonged isovolumic relaxation period (IRP) reflecting reduced rate of fall of left ventricular pressure. Eighty four patients with proven hypertrophic cardiomyopathy and 31 normal subjects were studied by simultaneous record...

journal_title：Postgraduate medical journal

authors： Alvares RF,Goodwin JF

更新日期：1986-06-01 00:00:00

abstract：:Largyngotracheal and pharyngoesophageal tears following minor blunt trauma to the neck are uncommon. A child with such an injury is reported and the modes of diagnosis and management are discussed. Patients may initially present with minimal signs and symptoms, but their condition may deteriorate rapidly or insidiousl...

journal_title：Postgraduate medical journal

authors： Back GW,Banfield G

更新日期：1999-09-01 00:00:00

abstract：:Central venous catheterization is not without hazard. Inadvertent placement in the pleural space can occur without the development of a pneumothorax and pressure measurements may appear misleadingly normal. This case report illustrates an effective method of diagnosing and draining an iatrogenic hydrothorax which resu...

journal_title：Postgraduate medical journal

authors： Steiger MJ,Morgan AG

更新日期：1990-08-01 00:00:00

abstract：:The painful pathological condition of the penis, priapism, is usually associated with serious destructive changes which lead to impotence if treatment is with-held or delayed. Conservative therapy is slow, uncertain and usually ineffective. Early surgical decompression of the corpora cavernosa, repeated if necessary, ...

journal_title：Postgraduate medical journal

authors： Ihekwaba FN,Lawani J

更新日期：1981-02-01 00:00:00

abstract：:Long intergenic non-coding RNA 01296 (LINC01296) has been reported to play an important role in many human malignancies, but a consistent perspective has not been established now. To explore the prognostic value of LINC01296 in different types of human solid malignant tumours, we performed this meta-analysis.An electr...

journal_title：Postgraduate medical journal

authors： Dai C,Dai C,Ni H,Xu Z

更新日期：2020-01-01 00:00:00

abstract：:Seventy-eight clinically euthyroid patients with atrial dysrhythmias, either established or paroxysmal, and sixty-three patients in sinus rhythm with coronary disease were screened for hyperthyroidism using thyroid function tests including the thyroid-stimulating hormone (TSH) response to thyrotrophin-releasing hormon...

journal_title：Postgraduate medical journal

authors： Symons C,Myers A,Kingstone D,Boss M

更新日期：1978-10-01 00:00:00

abstract：INTRODUCTION:Doctors in all specialties are involved in making "do not attempt resuscitation" (DNAR) decisions; this can be a difficult and challenging process. Guidelines exist to provide an ethical and legal framework for the process and documentation of these decisions. OBJECTIVE:To audit the documentation of resus...

journal_title：Postgraduate medical journal

authors： Harris D,Davies R

更新日期：2007-02-01 00:00:00

abstract：:We report a 44 year old man who developed external ophthalmoplegia and predominantly respiratory, truncal and bulbar weakness with brisk reflexes, histological evidence of an inflammatory myopathy and a high titre of acetylcholine receptor antibodies, one month after starting hydroxyurea and allopurinol for chronic my...

journal_title：Postgraduate medical journal

authors： Bergin PS,Gale AN

更新日期：1993-04-01 00:00:00

abstract：:A 27 year old woman with hepato-lenticular degeneration (Wilson's disease) was found to have primary hepatocellular carcinoma (PHC) three and a half years after she was started on treatment with D-penicillamine. The tumour was resected since when she has remained well. Her liver function tests were normal throughout t...

journal_title：Postgraduate medical journal

authors： Guan R,Oon CJ,Wong PK,Foong WC,Wee A

更新日期：1985-04-01 00:00:00

abstract：:A case of Meckel's diverticulum in a middle-aged man presenting acutely with haematemesis and melaena is reported. Such a presentation has not to our knowledge been previously reported in this age group. ...

journal_title：Postgraduate medical journal

authors： Shaunak S,O'Donohue J

更新日期：1983-12-01 00:00:00

abstract：:Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal ...

journal_title：Postgraduate medical journal

authors： McRipley RJ,Erhard PJ,Schwind RA,Whitney RR

更新日期：1979-09-01 00:00:00

abstract：:The addition of amino acid supplements to peritoneal dialysis fluid has been studied in 8 patients with compromised renal function requiring peritoneal dialysis. By the addition of 10 ml of Vamin-glucose solution to each one litre of peritoneal dialysate, amino acid losses were curtailed, no significant alterations oc...

journal_title：Postgraduate medical journal

authors： Jackson MA,Talbot S,Thomas DW,Lee HA

更新日期：1979-09-01 00:00:00

abstract：:Defence against the reactive oxidants produced during aerobic metabolism is a complex process and is provided by a system of enzymes and antioxidant compounds capable of preventing excess radical production, neutralising free radicals and repairing the damage caused by them. Regulation of the antioxidant system must p...

journal_title：Postgraduate medical journal

authors： Szaleczky E,Prechl J,Fehér J,Somogyi A

更新日期：1999-01-01 00:00:00

abstract：:The case is reported of a patient presenting with recurrent acute myocardial infarction due to stent thrombosis resulting from possible clopidogrel resistance caused by interaction between clopidogrel and anti-tuberculosis drugs. A brief overview of drug interaction as a risk factor for clopidogrel resistance is given...

journal_title：Postgraduate medical journal

authors： Srinivasan M,Smith D

更新日期：2008-04-01 00:00:00

abstract：:Hypersensitivity reactions to chemotherapy drugs pose significant difficulties in management, especially when no suitable alternative is available or acceptable and delay in continuation of treatment may be life-threatening. Such reactions may be IgE- or non-IgE-mediated and have varied manifestations. Timely recognit...

journal_title：Postgraduate medical journal

authors： Tham EH,Cheng YK,Tay MH,Alcasabas AP,Shek LP

更新日期：2015-03-01 00:00:00

abstract：:This study examines clinical features of late onset anorexia nervosa. This involved the scrutiny of a large database of patients with anorexia nervosa comprising data gathered at standardized initial assessments over the period 1960-1990. Patients with a late onset were compared to other selected patient samples. The ...

journal_title：Postgraduate medical journal

authors： Joughin NA,Crisp AH,Gowers SG,Bhat AV

更新日期：1991-11-01 00:00:00

abstract：INTRODUCTION:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been caused the greatest pandemic of our century. Many of the deaths related to it are due to a systemic inflammatory response, which has been called 'cytokine storm'. OBJECTIVES:We developed a comprehensive review of the pathophysiology mec...

journal_title：Postgraduate medical journal

authors： Mélo Silva Júnior ML,Souza LMA,Dutra REMC,Valente RGM,Melo TS

更新日期：2020-10-02 00:00:00

abstract：:Two cases of coeliac disease associated with thyroid enlargement are presented. One had a large simple adenomatous goitre which was removed surgically and the other had histological confirmation of lymphadenoma (Hashimoto's disease). ...

journal_title：Postgraduate medical journal

authors： Robinson TJ

更新日期：1977-02-01 00:00:00

abstract：AIM:To establish an updated clinical profile of adenocarcinoma of the lung. DESIGN:Retrospective review of clinical charts, chest radiography, and computed tomography of consecutive patients who attended Queen Mary Hospital in Hong Kong between June 1995 and December 1997. RESULTS:In the 115 patients studied, 13% wer...

journal_title：Postgraduate medical journal

authors： Lam B,Lam WK,Lam CL,Ooi GC,Ho JC,Wong MP,Tsang KW

更新日期：2001-11-01 00:00:00

abstract：:The efficacy of ranitidine (150 mg twice daily) and cimetidine (200 mg three times daily and 400 mg at night) in the short-term healing of duodenal ulcer has been assessed in a randomized controlled trial involving 106 patients. There were 3 drop-outs. Forty-two out of 53 patients (79%) treated with ranitidine had hea...

journal_title：Postgraduate medical journal

authors： Lee FI,Fielding JD,Costello FT

更新日期：1983-02-01 00:00:00

abstract：:A 77 year old man with digital gangrene of his left hand had anti-phospholipid antibodies, the lupus anticoagulant and antcardiolipin antibodies. This patient, as far as we are aware, is the first elderly person to present in such fashion with this uncommon syndrome. ...

journal_title：Postgraduate medical journal

authors： Roche SW,Niriella DC,O'Mahoney A,Cayley AC

更新日期：1989-11-01 00:00:00

abstract：:A patient is described who developed mild hyponatraemia on two occasions when treated with bendrofluazide alone, but severe hyponatraemia when treated with the combination of enalapril and bendrofluazide. ...

journal_title：Postgraduate medical journal

authors： Collier JG,Webb DJ

更新日期：1987-12-01 00:00:00

abstract：:Three patients with lung carcinoid related Cushing's syndrome (LCRCS) treated at Frenchay Hospital, Bristol between 1984 and 1994 are described. The first patient presented with hyperpigmentation 13 years after bilateral adrenalectomy. The second patient had no recurrence or metastases 14 years after removal of a typi...

journal_title：Postgraduate medical journal

authors： Amer KM,Ibrahim NB,Forrester-Wood CP,Saad RA,Scanlon M

更新日期：2001-07-01 00:00:00