Abstract:
OBJECTIVE:Iron deficiency anemia is known to impair cognitive and psychomotor development. The zinc protoporphyrin/heme (ZPP/H) ratio is a simple, accurate, and sensitive laboratory screening test that detects early iron depletion before the onset of anemia. The objective of this work was to evaluate this test in a primary pediatric practice setting. METHODS:The iron status of a cohort of 361 children was screened during routine examinations at a community pediatric practice. Whole blood hemoglobin concentration, hematocrit ratio, serum transferrin saturation, ferritin concentration, and the ZPP/H ratio were measured. The ZPP/H ratio then was evaluated as a single indicator of iron status by comparing it with other tests for detecting the onset of iron deficiency and for monitoring recovery after iron supplementation. RESULTS:Significant age- and sex-related differences in the ZPP/H ratio were found. In this cohort, serum ferritin concentration and the ZPP/H ratio independently identified the same fraction of iron-deficient patients (3%-4%), and both tests were more specific than was either hemoglobin or hematocrit. A concordance of three iron status parameters changed the prediction of iron deficiency to =1%. Children <3 years of age and adolescent girls had significantly higher ZPP/H results. CONCLUSION:The prevalence of iron deficiency anemia in the typical healthy American pediatric population is low, but iron deficiency without anemia remains relatively common at some stages of development. Increase in the ZPP/H ratio is demonstrated to be a sensitive, specific, and cost-effective test for identifying preanemic iron deficiency in a community pediatric practice. anemia, nutrition, development.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Rettmer RL,Carlson TH,Origenes ML,Jack RM,Labb RFdoi
10.1542/peds.104.3.e37subject
Has Abstractpub_date
1999-09-01 00:00:00pages
e37issue
3eissn
0031-4005issn
1098-4275journal_volume
104pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:OBJECTIVE:This study examined the 24-month outcomes of a randomized controlled trial of a group-based behavioral weight control (BWC) program combined with either activity-based peer intervention or aerobic exercise. METHODS:At baseline, 118 obese adolescents (68% female; BMI = 31.41 ± 3.33) ages 13 to 16 years (mean ...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2011-3283
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:Adverse childhood experiences (ACEs) may have long-term consequences on at-risk behaviors that lead to an increased risk of sexually transmitted diseases (STDs) during adulthood. Therefore, we examined the relationship between ACEs and subsequent STDs for both men and women. METHODS:A total of 9323 (4263 men...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.1.e11
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:For asthma, attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder (ASD), the objectives were to (1) describe the percent increases in prevalence and comorbidity and how these vary by poverty status, and (2) examine the extent to which poverty status is a predictor of higher than avera...
journal_title:Pediatrics
pub_type: 杂志文章,收录出版
doi:10.1542/peds.2016-2539
更新日期:2017-03-01 00:00:00
abstract::Primary aldosteronism resulting from an adrenal adenoma is rare in children. An 8 1/2-year-old girl was found to have hypertension and spontaneous hypokalemia, both detected as incidental findings. Subsequent investigations revealed inappropriately elevated levels of plasma and urinary aldosterone with suppressed plas...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract:OBJECTIVES:Adolescents with justice system involvement have high rates of physical and behavioral health disorders and are potentially high users of costly health care services. We examined emergency department (ED) and hospital use among a national sample of adolescents with various levels of justice involvement. MET...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-1144
更新日期:2017-11-01 00:00:00
abstract:CONTEXT:Rates of rapid second births among low-income black adolescent mothers range from 20% to 50%. Most efforts to prevent rapid second births have been unsuccessful. OBJECTIVES:There were 4 objectives: (1) to examine whether a home-based mentoring intervention was effective in preventing second births within 2 yea...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2005-2318
更新日期:2006-10-01 00:00:00
abstract::This clinical report defines common terms of use and provides information on current practice, research, and limitations of assistive technology that can be used in systems for communication. The assessment process to determine the best devices for use with a particular child (ie, the best fit of a device) is also rev...
journal_title:Pediatrics
pub_type: 杂志文章,实务指引
doi:10.1542/peds.2008-0695
更新日期:2008-06-01 00:00:00
abstract::Two patients had prolonged retention of small round foreign bodies in the stomach. Both patients had a history of a pyloromyotomy. Radiographic examination revealed a prepyloric web in one patient and a deformed pylorus in the other. These findings were confirmed by surgery. ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00
abstract::In an attempt to determine whether iron-fortified infant formulas produced gastrointestinal symptoms in infants, we fed two similar formulas, one with and one without iron fortification, to a group of 93 term infants upon discharge from the nursery on the third day of life. Infants were fed the formulas for a period o...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1980-08-01 00:00:00
abstract:BACKGROUND:Studies suggest that giving newly born preterm infants sustained lung inflation (SLI) may decrease their need for mechanical ventilation (MV) and improve their respiratory outcomes. METHODS:We randomly assigned infants born at 25 weeks 0 days to 28 weeks 6 days of gestation to receive SLI (25 cm H2O for 15 ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2014-1692
更新日期:2015-02-01 00:00:00
abstract::Data for this article, as in previous reports, are drawn principally from the Monthly Vital Statistics Report, published by the National Center for Health Statistics. The international data come from the Demographic Yearbook and the quarterly Population and Vital Statistics Report, both published by the Statistical Of...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Physicians have a major influence on parental vaccine decisions. We tested a physician-targeted communication intervention designed to (1) reduce vaccine hesitancy in mothers of infants seen by trained physicians and (2) increase physician confidence in communicating about vaccines. METHODS:W...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2014-3199
更新日期:2015-07-01 00:00:00
abstract::Deep vein thrombophlebitis (DVT) and septic pulmonary emboli (PE) are rare in children. The association of DVT and acute disseminated staphylococcal disease (DSD) during childhood has not been previously reported. We report 3 children who developed a triad of DVT, septic PE, and acute osteomyelitis with Staphylococcus...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.6.e87
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:We investigated the effects of self-regulation of slow cortical potentials for children with attention-deficit/hyperactivity disorder. Slow cortical potentials are slow event-related direct-current shifts of the electroencephalogram. Slow cortical potential shifts in the electrical negative direction reflect ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2478
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:Earlier we found black-white contrast in insulin levels in adolescents. The purpose of this study is to assess whether this difference is attributable to alterations in insulin secretion and/or clearance. METHODS:Fasting circulating insulin and C-peptide concentrations were examined in 1157 adolescents aged ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::The fragile X syndrome, a common X-linked form of mental retardation and autism, affects females as well as males. Previous work has shown that approximately 35% of heterozygotes (women who carry the fragile X gene) demonstrate cognitive impairment. Thirty-two girls, 18 years or younger, who demonstrate the fragile X ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract::The epidemiology of Helicobacter pylori infection was studied in 245 healthy children (between 3 and 20 years of age) who presented for day surgery at Arkansas Children's Hospital. H pylori infection was identified serologically using an enzyme-linked immunosorbent assay to detect the presence of IgG against the high ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract::The cardiovascular manifestations of the Marfan syndrome in older children and adults have been well described. Clinical, radiographic, and echocardiographic data regarding three patients with severe perinatal Marfan syndrome are described. Two of these patients had the syndrome at birth and died in infancy. The syndr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract::Vitamin A delivery was studied in total parenteral nutrition as used for neonates. Although the data show that the patient receives more vitamin A than dictated by known needs or advised intakes, delivery to the patient is roughly one third of that which would be predicted from the initial intravenous solution composi...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract:OBJECTIVE:To determine whether medically unexplained recurrent abdominal pain (RAP) in childhood predicts abdominal pain, irritable bowel syndrome (IBS), other somatic complaints, and psychiatric symptoms and disorders in young adulthood. METHODS:A sample of 28 young adults evaluated for RAP between the ages of 6 and ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.1.e1
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Family-centered rounds (FCRs) have become standard of care, despite the limited evaluation of FCRs' benefits or interventions to support high-quality FCR delivery. This work examines the impact of the FCR checklist intervention, a checklist and associated provider training, on performance of F...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2016-1688
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Small pilot studies support the appropriateness of engaging adolescents with chronic or life-limiting illnesses in pediatric advance care planning (pACP). We do not yet know if pACP is acceptable, feasible, and worthwhile, even if emotionally intense, in a fully powered randomized controlled tr...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2016-1854
更新日期:2016-12-01 00:00:00
abstract::A thin and semipermeable polyurethane membrane adherently applied to premature neonates as an artificial skin was investigated as an atraumatic surface barrier sufficient to reduce transepidermal water loss without inhibiting natural infant skin development during the first few days of life. A sample group of 18 neona...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract::In 1967 the American Academy of Pediatrics published standards for periodic health supervision visits. In 1972 and 1975, in response to changes in child health needs, the guidelines were revised. The current AAP periodicity guidelines, adopted in 1981, provide for reasonable care and meet the minimum requirements for ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1984-11-01 00:00:00
abstract:BACKGROUND:The impact of secondhand marijuana smoke exposure on children is unknown. New methods allow for the detection of marijuana smoke exposure in children. METHODS:We studied children who were hospitalized in Colorado and had a parent participating in a smoking cessation study; all children had urine samples rem...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2018-0820
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVES:The purpose of this work was to identify barriers to physical activity in children with asthma and to compare their customary activity levels, BMI and emotional well-being with that of children with other medical conditions. It was hypothesized that children with asthma would have higher BMI and lower levels...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1846
更新日期:2006-12-01 00:00:00
abstract::Since the outbreaks of neonatal necrotizing enterocolitis occurring in maternity hospitals of Paris and suburbs in 1979-1980, it has been possible to examine by light and electron microscopy gut specimens from ten newborns with this illness. Coronavirus-like particles, enclosed in intracytoplasmic vesicles of damaged ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1984-02-01 00:00:00
abstract:OBJECTIVE:To assess the usefulness of laboratory parameters, including peripheral white blood cell (WBC) count, C-reactive protein (CRP) concentration, erythrocyte sedimentation rate (ESR), and microscopic urinalysis (UA), for identifying febrile infants younger than 8 weeks of age at risk for urinary tract infection (...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.2.e20
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Neonatal encephalopathy (NE) is a major predictor of death and long-term neurologic disability, but there are few studies of antecedents of NE. OBJECTIVES:To identify antecedents in a large registry of infants who had NE. METHODS:This was a maternal and infant record review of 4165 singleton neonates, gest...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-0714
更新日期:2012-11-01 00:00:00
abstract::During a 12-month period 80 children greater than 3 months of age seen at an emergency room with acute fevers greater than or equal to 39.7 C (103.5 F) and no localizing signs of infection were studied using blood and buffy coat cultures to isolate bacteria and viruses. Bacteremia was identified in three children (3.8...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-08-01 00:00:00