Iron-fortified formulas and gastrointestinal symptoms in infants: a controlled study, With the cooperation of The Syracuse Consortium for Pediatric Clinical Studies.

Abstract:

:In an attempt to determine whether iron-fortified infant formulas produced gastrointestinal symptoms in infants, we fed two similar formulas, one with and one without iron fortification, to a group of 93 term infants upon discharge from the nursery on the third day of life. Infants were fed the formulas for a period of 42 days while their mothers kept detailed daily records of all gastrointestinal symptoms. A total of 49 infants were fed the non-iron-fortified formula and 44 infants were fed the iron-fortified formula. Review of the records revealed no differences in the number of stools per day, the description of the stools, the number of days without stools, the incidence or frequency of colic, spitting-up, or vomiting. We conclude that the feeding of iron-fortified formulas to infants does not produce an increased incidence of gastrointestinal symptoms or signs.

journal_name

Pediatrics

journal_title

Pediatrics

authors

subject

Has Abstract

pub_date

1980-08-01 00:00:00

pages

168-70

issue

2

eissn

0031-4005

issn

1098-4275

journal_volume

66

pub_type

临床试验,杂志文章,随机对照试验
  • Hypokalemic metabolic alkalosis in normotensive infants with elevated plasma renin activity and hyperaldosteronism: role of dietary chloride deficiency.

    abstract::The role of chloride deficiency in the generation of hypokalemic metabolic alkalosis with elevated plasma renin activity and plasma aldosterone levels, normal blood pressure, and a renal concentrating defect was studied in six infants given a soy formula that was deficient in chloride. A deceleration in linear growth,...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Roy S 3rd,Arant BS Jr

    更新日期:1981-03-01 00:00:00

  • Use of wireless capsule endoscopy in the management of severe Henoch-Schonlein purpura.

    abstract::Henoch-Schonlein purpura is a multisystem vasculitis that primarily affects children. Characteristic symptoms include purpura of the lower extremities and buttocks, abdominal pain, arthralgias, and hematuria. Gastrointestinal bleeding occurs in approximately 50% of children and, although often self-limiting, can be si...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-3111

    authors: Preud'Homme DL,Michail S,Hodges C,Milliken T,Mezoff AG

    更新日期:2006-09-01 00:00:00

  • One-Year Language Outcomes in Toddlers With Language Delays: An RCT Follow-up.

    abstract:OBJECTIVES:The current study is a 1-year follow-up analysis of data from a randomized controlled trial of Enhanced Milieu Teaching (EMT) for toddlers with language delays. Outcomes and predictors of child language and parent intervention implementation were examined 6 and 12 months after the end of the intervention. M...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2016-3646

    authors: Hampton LH,Kaiser AP,Roberts MY

    更新日期:2017-11-01 00:00:00

  • Intracranial hemorrhage in infants and children with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome).

    abstract:OBJECTIVE:Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia. Most cases are caused by mutations in the endoglin gene on chromosome 9 (HHT type 1) or the activin receptor-like kinase 1 gene on chromosome 12 (HHT type 2), which leads to telangiectases and arteriovenous malformations ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.109.1.e12

    authors: Morgan T,McDonald J,Anderson C,Ismail M,Miller F,Mao R,Madan A,Barnes P,Hudgins L,Manning M

    更新日期:2002-01-01 00:00:00

  • Family member knowledge of children's medical problems: the need for universal application of an emergency data set.

    abstract:OBJECTIVE:Advances in medical care have led to a growing population of special needs children who are at risk for suboptimal care when they present to a physician with no previous knowledge of their medical history. This risk may be amplified in the emergency department setting when time-sensitive interventions must be...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.102.2.367

    authors: Carraccio CL,Dettmer KS,duPont ML,Sacchetti AD

    更新日期:1998-08-01 00:00:00

  • Discrepancies between direct and indirect blood pressure measurements using various recommendations for arm cuff selection.

    abstract:OBJECTIVE:The current recommendation for choosing an appropriate size cuff for measuring blood pressure (BP) is a bladder width to equal 40% of the upper arm circumference (UAC). However, most physicians use the older two-thirds or three-fourths upper arm length (UAL) recommendations to choose a cuff. The aim of this s...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.110.5.920

    authors: Clark JA,Lieh-Lai MW,Sarnaik A,Mattoo TK

    更新日期:2002-11-01 00:00:00

  • The Revised WIC Food Package and Child Development: A Quasi-Experimental Study.

    abstract:BACKGROUND AND OBJECTIVES:The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), one of the largest US safety net programs, was revised in 2009 to be more congruent with dietary guidelines. We hypothesize that this revision led to improvements in child development. METHODS:Data were drawn f...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-1853

    authors: Guan A,Hamad R,Batra A,Bush NR,Tylavsky FA,LeWinn KZ

    更新日期:2021-02-01 00:00:00

  • Self-regulation of slow cortical potentials: a new treatment for children with attention-deficit/hyperactivity disorder.

    abstract:OBJECTIVE:We investigated the effects of self-regulation of slow cortical potentials for children with attention-deficit/hyperactivity disorder. Slow cortical potentials are slow event-related direct-current shifts of the electroencephalogram. Slow cortical potential shifts in the electrical negative direction reflect ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-2478

    authors: Strehl U,Leins U,Goth G,Klinger C,Hinterberger T,Birbaumer N

    更新日期:2006-11-01 00:00:00

  • Is Chlamydia pneumoniae infection associated with stroke in children with sickle cell disease?

    abstract:BACKGROUND:Stroke is often a devastating complication of sickle cell disease (SCD). Most children with SCD-related stroke have stenotic and occlusive disease of cerebral blood vessels due to intimal hyperplasia. This hyperplasia is hypothesized to result from an inflammatory response similar to that in atherosclerosis ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.113.4.e318

    authors: Goyal M,Miller ST,Hammerschlag MR,Gelling M,Gaydos CA,Hardick J,Wood BJ,Reznik T,Rao SP

    更新日期:2004-04-01 00:00:00

  • Mental Health Services Utilization and Expenditures Among Children Enrolled in Employer-Sponsored Health Plans.

    abstract:BACKGROUND AND OBJECTIVES:Mental illness in children increases the risk of developing mental health disorders in adulthood, and reduces physical and emotional well-being across the life course. The Mental Health Parity and Addiction Equity Act (MHPAEA, 2008) aimed to improve access to mental health treatment by requiri...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-2786G

    authors: Walter AW,Yuan Y,Cabral HJ

    更新日期:2017-05-01 00:00:00

  • Cobalamin C defect presenting with isolated pulmonary hypertension.

    abstract::Cobalamin C (cblC) defect is the most common inborn error of vitamin B12 metabolism. Clinical features vary as does the severity of the disease. In most cases, the clinical symptoms of cblC defect tend to appear during infancy or early childhood as a multisystem disease with severe neurologic, ocular, hematologic, ren...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-1945

    authors: Iodice FG,Di Chiara L,Boenzi S,Aiello C,Monti L,Cogo P,Dionisi-Vici C

    更新日期:2013-07-01 00:00:00

  • Suicide and suicide attempts in adolescents. Committee on Adolescents. American Academy of Pediatrics.

    abstract::Suicide is the third leading cause of death for adolescents 15 to 19 years old.(1) Pediatricians can help prevent adolescent suicide by knowing the symptoms of depression and other presuicidal behavior. This statement updates the previous statement(2) by the American Academy of Pediatrics and assists the pediatrician ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:2000-04-01 00:00:00

  • Use of trained mothers to teach interviewing skills to first-year medical students: a follow-up study.

    abstract::This report describes an attempt to evaluate the effectiveness of "trained mother" interviews early in the medical school curriculum. As an adjunct to a first-year course that teaches interviewing techniques, half of the students were exposed to an interview with one of three trained mothers early in the course. This ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Stillman PL,Sabers DL,Redfield DL

    更新日期:1977-08-01 00:00:00

  • Collaborative office rounds: continuing education in the psychosocial/developmental aspects of child health.

    abstract:OBJECTIVES:In recent years there has been increasing emphasis on the mental health aspects of primary health care for children and adolescents. The Health Resources and Services Administration's Maternal and Child Health Bureau has contributed to efforts aimed at strengthening primary care not only in early identificat...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.99.4.e5

    authors: Fishman ME,Kessel W,Heppel DE,Brannon ME,Papai JJ,Bryn SD,Nora AH,Hutchins VL

    更新日期:1997-04-01 00:00:00

  • Infant Pulmonary Function Testing and Phenotypes in Severe Bronchopulmonary Dysplasia.

    abstract:BACKGROUND:The definition of severe bronchopulmonary dysplasia (sBPD) is based on respiratory support needs. The management of a patient with sBPD remains empirical and is highly variable among providers. Our objective in this study was to test the hypothesis that infant pulmonary function testing (iPFT) would reveal d...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-3350

    authors: Shepherd EG,Clouse BJ,Hasenstab KA,Sitaram S,Malleske DT,Nelin LD,Jadcherla SR

    更新日期:2018-05-01 00:00:00

  • Prediction of digoxin treatment failure in infants with supraventricular tachycardia: role of transesophageal pacing.

    abstract::Transesophageal atrial pacing was used to initiate and terminate tachycardia in 24 infants (seven female and 17 male, aged 1 to 34 days) with ECG documentation of supraventricular tachycardia. Six infants received no chronic treatment, and chronic oral digoxin prophylaxis was administered to 18 infants in an effort to...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Benson DW Jr,Dunnigan A,Benditt DG,Thompson TR,Narayan A,Boros S

    更新日期:1985-02-01 00:00:00

  • Severe varicella associated with steroid use.

    abstract:OBJECTIVE:To evaluate whether corticosteroid use is associated with severe varicella. DESIGN:The odds of corticosteroid exposure were compared among 35 children with severe varicella and 10,000 control subjects. RESULTS:Five (26.3%) of 19 case patients without known immunosuppression had received steroids within 30 d...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Dowell SF,Bresee JS

    更新日期:1993-08-01 00:00:00

  • Health literacy and child health outcomes: a systematic review of the literature.

    abstract:OBJECTIVES:To review the relationship between parent and child literacy and child health outcomes and interventions designed to improve child health outcomes for children or parents with low literacy skills. METHODS:We searched Medline and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) for artic...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2009-1162B

    authors: DeWalt DA,Hink A

    更新日期:2009-11-01 00:00:00

  • The effect of maternal antibody on the serologic response and the incidence of adverse reactions after primary immunization with acellular and whole-cell pertussis vaccines combined with diphtheria and tetanus toxoids.

    abstract:OBJECTIVE:To evaluate the effect of maternally derived antibody on the immunogenicity and reactogenicity of acellular (DTaP) or whole-cell (DTP) pertussis vaccine with diphtheria and tetanus toxoids combined. METHODS:A total of 2342 infants were randomized to receive one of 13 DTaP or 2 DTP vaccines at 2, 4, and 6 mon...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors: Englund JA,Anderson EL,Reed GF,Decker MD,Edwards KM,Pichichero ME,Steinhoff MC,Rennels MB,Deforest A,Meade BD

    更新日期:1995-09-01 00:00:00

  • Early Intervention for Children With Autism Spectrum Disorder Under 3 Years of Age: Recommendations for Practice and Research.

    abstract::This article reviews current evidence for autism spectrum disorder (ASD) interventions for children aged <3 years, based on peer-reviewed articles published up to December 2013. Several groups have adapted treatments initially designed for older, preschool-aged children with ASD, integrating best practice in behaviora...

    journal_title:Pediatrics

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1542/peds.2014-3667E

    authors: Zwaigenbaum L,Bauman ML,Choueiri R,Kasari C,Carter A,Granpeesheh D,Mailloux Z,Smith Roley S,Wagner S,Fein D,Pierce K,Buie T,Davis PA,Newschaffer C,Robins D,Wetherby A,Stone WL,Yirmiya N,Estes A,Hansen RL,McPartlan

    更新日期:2015-10-01 00:00:00

  • Dating violence and associated sexual risk and pregnancy among adolescent girls in the United States.

    abstract:OBJECTIVES:To assess the annual prevalence of physical violence from dating partners among a representative sample of sexually experienced adolescent girls attending US public and private high schools, as well as sexual risk behaviors and pregnancy among this population. DESIGN, SETTING, PARTICIPANTS, AND MEASURES:Fem...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.114.2.e220

    authors: Silverman JG,Raj A,Clements K

    更新日期:2004-08-01 00:00:00

  • Yersinia enterocolitica arthritis.

    abstract::Human infections with Yersinia were first recognized and reported in upper New York State almost 40 years ago. Recently, there have been increasing numbers of reports from Scandinavia of episodes of polyarthritis associated with Yersinia infections. A 6-month-old girl from upstate New York had a fever of 40 C for two ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Jacobs JC

    更新日期:1975-02-01 00:00:00

  • Clinical Prediction Rule for Distinguishing Bacterial From Aseptic Meningitis.

    abstract:BACKGROUND:New biomarkers like procalcitonin and C-reactive protein may help design an accurate decision support tool used to identify children with pleocytosis at low or high risk of bacterial meningitis. Our objective was to develop and validate a score (that we call the meningitis score for emergencies [MSE]) to dis...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-1126

    authors: Mintegi S,García S,Martín MJ,Durán I,Arana-Arri E,Fernandez CL,Benito J,Hernández-Bou S,Meningitis Group of the Spanish Society of Pediatric Emergencies.

    更新日期:2020-09-01 00:00:00

  • Using a preprinted order sheet to reduce prescription errors in a pediatric emergency department: a randomized, controlled trial.

    abstract:OBJECTIVE:Medication errors are common among pediatric patients and in emergency departments (EDs). Such errors may lead to prolonged hospitalization, unnecessary diagnostic tests and treatments, and death. The objective of this study was to determine whether the use of a structured order sheet reduces the incidence of...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2004-2016

    authors: Kozer E,Scolnik D,MacPherson A,Rauchwerger D,Koren G

    更新日期:2005-12-01 00:00:00

  • Perinatal Risk Factors for Feeding and Eating Disorders in Children Aged 0 to 3 Years.

    abstract:OBJECTIVE:To describe the incidence, age at diagnosis, and associations between perinatal risk factors of feeding and eating disorders (FED) diagnosed at hospital in children aged 0 to 3 years. METHODS:A nationwide cohort of 901 227 children was followed until 48 months of age in the national registers from 1997 to 20...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-2575

    authors: Hvelplund C,Hansen BM,Koch SV,Andersson M,Skovgaard AM

    更新日期:2016-02-01 00:00:00

  • Developmental Assessments in Preterm Children: A Meta-analysis.

    abstract:CONTEXT:Developmental outcomes of very preterm (gestational age ≤32 weeks) or very low birth weight (<1500 g) children are commonly reported before age 3 years although the predictive validity for later outcomes are uncertain. OBJECTIVE:To determine the validity of early developmental assessments in predicting school-...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1542/peds.2016-0251

    authors: Wong HS,Santhakumaran S,Cowan FM,Modi N,Medicines for Neonates Investigator Group.

    更新日期:2016-08-01 00:00:00

  • Fibromyalgia syndrome in children and adolescents: clinical features at presentation and status at follow-up.

    abstract:OBJECTIVES:To 1) describe the characteristic features of fibromyalgia syndrome (FS) in a pediatric population, 2) note similarities and differences with FS in adults, and 3) determine outcome after treatment. SETTING AND DESIGN:The Pediatric Rheumatology Clinic at the University of Rochester Medical Center is staffed ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.101.3.377

    authors: Siegel DM,Janeway D,Baum J

    更新日期:1998-03-01 00:00:00

  • Primary care physician supply and children's health care use, access, and outcomes: findings from Canada.

    abstract:OBJECTIVES:To describe the relationship of primary care physician (PCP) supply for children and measures of health care access, use, and outcomes. METHODS:We conducted a population-based, cross-sectional study of all Ontario children from 2003 to 2005. We used health administrative data to calculate county-level suppl...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-2821

    authors: Guttmann A,Shipman SA,Lam K,Goodman DC,Stukel TA

    更新日期:2010-06-01 00:00:00

  • The clinical phenotype of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria): case reports of 23 new patients.

    abstract:OBJECTIVES:To further define the clinical spectrum of the disease for pediatric and metabolic specialists, and to suggest that the general pediatrician and pediatric neurologist consider succinic semialdehyde dehydrogenase (SSADH) deficiency in the differential diagnosis of patients with (idiopathic) mental retardation...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.99.4.567

    authors: Gibson KM,Christensen E,Jakobs C,Fowler B,Clarke MA,Hammersen G,Raab K,Kobori J,Moosa A,Vollmer B,Rossier E,Iafolla AK,Matern D,Brouwer OF,Finkelstein J,Aksu F,Weber HP,Bakkeren JA,Gabreels FJ,Bluestone D,Barron T

    更新日期:1997-04-01 00:00:00

  • Should central venous catheters be removed as soon as candidemia is detected in neonates?

    abstract:BACKGROUND:Controversy exists regarding the most appropriate acute management of central venous catheters (CVCs) in neonates with candidemia, with up to two thirds of neonatologists preferring to attempt antifungal therapy without removing CVCs. OBJECTIVE:To determine whether CVCs should be removed as soon as candidem...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.106.5.e63

    authors: Karlowicz MG,Hashimoto LN,Kelly RE Jr,Buescher ES

    更新日期:2000-11-01 00:00:00