Abstract：
AIM:To validate up-to-date policy of immunosuppressive therapy of patients with aplastic anemia (AA) which has developed either at acute or chronic phase of viral hepatitis. MATERIALS AND METHODS:16 patients with AA detected within 6 months (9 patients) or 12-36 months (7 patients) after acute viral hepatitis received immunosuppressive therapy (antilymphocytic globulin, cyclosporin A, splenectomy). RESULTS:Posthepatitis aplastic anemias ran a severe and treatment-resistant course in most cases. The immunosuppressive therapy produced a response in 44% of the patients. AA following acute viral hepatitis demands intensive and long-term immunosuppressive therapy with antilymphocytic globulin, cyclosporin A, splenectomy (in some cases) to achieve a persistent clinicohematological remission.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Mikhaĭlova EA,Iadrikhinskaia VN,Savchenko VGsubject
Has Abstractpub_date
1999-01-01 00:00:00pages
64-9issue
7eissn
0040-3660issn
2309-5342journal_volume
71pub_type
杂志文章abstract：AIM:To evaluate the effect of sitagliptin in combination with metformin on glucose toxicity and lipotoxicity in patients with type 2 diabetes mellitus. SUBJECTS AND METHODS:. Eighty-two overweight and dyslipidemic patients (mean age 55.3 +/- 9.1 years) who had not achieved the goal levels of glycated hemoglobin (HbA1c...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2014-01-01 00:00:00
abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) are extensively used in the treatment of rheumatic diseases to relieve pain and signs of inflammation. However, when treated for ankylosing spondylosis (AS), NSAIDS exert both symptomatic and structure-modifying effects, by slowing down the development of vertebral ankylos...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：
更新日期：2014-01-01 00:00:00
abstract：:One of the mechanisms responsible for occupational dermatoses of constructors in contact with Cr-containing substances is supposed to be antibodies production as a result of Cr ion migration in the blood. The authors' measurements led them to the conclusions that no significant rise in blood Cr content occurs with an ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Antiarrhythmic efficiency and specific effects of ethmozine, taken alone in increasing oral doses from 300 to 450 mg daily, were evaluated in 48 elderly and old coronary patients with stable supraventricular and ventricular extrasystoles (SVES, VES). It was demonstrated clinically and instrumentally (ECG, rhythmograph...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：AIM:To study nicotine dependence (ND) basing on special questionnaires and measurement of CO concentrations in the exhaled air. MATERIAL AND METHODS:350 smokers (318 males and 32 females) aged 20-57 years (mean age 37.1 +/- 7.3 years) were studied. ND was assessed by Fagerstrom test (FT), motivation to smoke and to qu...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Valsalva's sinus aneurysm is a congenital heart disease that may occur both as isolated abnormality or combined with other ailments. The present paper summarizes the results of the use in 20 patients of non-invasive research methods, namely ultrasound cardiography and Doppler's cardiography, in the diagnosis of Valsal...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The analysis of clinical and polycardiographic findings for 568 healthy males and females provided the basis for development of the criteria for standard exercise tolerance and normal range of cardiac cycle phases in relation to 5 ten-year age groups. With age, physical and mental performance was found to be on the de...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：AIM:To study generation of active oxygen forms in the whole blood of patients with chronic bronchitis and correction of the detected disorders. MATERIAL AND METHODS:By means of registration of spontaneous and staphylococcus-induced luminol-dependent chemiluminescence (LDCL) of the whole blood, generation of active oxy...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：AIM:To study effectiveness and tolerance of monoclonal antibodies to tumor necrosis factor (the drug remicade) in patients with rheumatoid arthritis (RA). MATERIAL AND METHODS:Remicade treatment results are considered for 25 RA patients receiving methotrexate the activity of which was inadequate for these patients. Re...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The article analyses cardiovascular morbidity and mortality with consideration of arterial hypertension (AH) involvement in terms of pathogenesis, chronicity of AH and its complications, causes of target organs affection. Such methods of treatment as symptomatic, basic, standard and situational are reviewed. ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:A possibility of life-time fibrinolysis activation with blast cells was studied in 54 patients with different variants of acute leukemia. The study showed that practically in all the variants of acute leukemia the content of fibrinolysis activators in the patients' blood was elevated. Active proteolytic enzymes of non...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：AIM:To study the survival and sequestration of transfused donor platelets labeled with 51Cr in patients with acute leukemia (AL). SUBJECTS AND METHODS:Seven donor volunteers and 39 patients with different forms with AL at various stages of polychemotherapy (PCT) were examined. Cytostatic therapy was accompanied by 51C...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:The 5- and 10-year survival rates of all 114 patients with primary DM were 89 and 81%, respectively. Significantly lower survival rates were noted in the patients receiving late and inadequate therapy. Corticosteroid therapy radically changed the outcome of DM, mainly due to early diagnosis and adequate therapy. A sta...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：AIM:To characterize elimination of some enzymes in intermittent hemofiltration (HF) in patients with acute renal failure (ARF). MATERIAL AND METHODS:22 patients with oliguric ARF have undergone 52 procedures of intermittent HF. Before the procedure and after it the activity of enzymes (AA, AP, ACE, LAP, GGT, GDG, AlAT...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：AIM:To assess clinical efficacy of mineral water and perindopril in convalescents after hemorrhagic fever with renal syndrome (HFRS) in outpatient setting. MATERIAL AND METHODS:The study covered 113 HFRS convalescents. HFRS was confirmed serologically. The patients were divided into three groups: group 1 (n = 50) rece...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:In the course of chronic active hepatitis (CAH) 61 patients (CAH of virus etiology in 75% and of obscure etiology in 25%) had 211 pregnancies which terminated in delivery in 80 (38%) cases, spontaneous abortions in 12 (6%) cases, and medical abortions in 119 (56%) cases. In most cases there was successful termination ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:New methods and treatment plans for patients with chronic coronary artery disease after endovascular interventions are currently introduced into clinical practice. It allows reducing hospital stay down to 24 hour, with discharge the next morning. This approach is called overnight stay. Using a similar strategy increas...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/00403660.2020.04.000532
更新日期：2020-05-19 00:00:00
abstract：:Short-term results of rehabilitation of 1046 CHD patients at a cardiological sanatorium in mountains at average altitude (1600 m above the sea level) were studied. Large focal myocardial infarction (MI) was found in 738 of them, small focal MI in 249, and acute focal myocardial dystrophy of ischemic genesis in 59. Of ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:The rate of Na-Li countertransport was studied in inpatients with essential hypertension (n = 59), chronic diffuse glomerulonephritis (n = 30), chronic pyelonephritis (n = 26), renovascular hypertension (n = 15) and in those with associated renovascular hypertension and essential hypertension (n = 4). Multiple regress...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：AIM:To specify risk factors affecting development and frequency of complications early after the bypass operation in direct myocardial revascularization. MATERIAL AND METHODS:455 patients with ischemic heart disease (IHD) of whom 392 (86.2%) had stable angina pectoris class III-IV, 25 (5.5%) had unstable angina pector...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：AIM:To evaluate efficacy of the International Prognostic Index (IPI) in relation to diffuse B-large cell lymphosarcoma (BLCLS), to identify significant prognostic factors. MATERIAL AND METHODS:The trial enrolled 121 patients (67 males and 54 females, mean age 54 years) suffering from BLCLS with involvement of the lymp...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:The authors assessed the time course of the S-T segment in 12 standard and monitor ECG leads and the time course of MB CPK fraction activity and Mg blood concentration in 34 patients with acute myocardial infarction. After the detection of thrombotic occlusion of the coronary artery they received thrombolytic therapy ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：AIM:To study left ventricular structural and functional changes in patients with chronic obstructive pulmonary disease (COPD) and chronic cor pulmonale (CCP) at different stages of a cardiac remodeling process. SUBJECTS AND METHODS:Echocardiography was used to examine 98 patients with COPD complicated by the developme...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：AIM:To estimate a relationship between the intima-media thickness (TIM), cardiovascular risk (CVR) factors, and the level of C-reactive protein (CRP) in gouty patients. SUBJECTS AND METHODS:Eighty-nine patients at an interattack interval were examined. The patients' mean age was 46.0 +/- 11.4 years; the duration of th...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:The authors analyze the results of the surgical treatment of patients with progressive essential hypertension (PEN). The treatment involved cryodestruction (adrenalectomy) of the right adrenal and autotransplantation of the left adrenal on the vascular peduncle into the transverse mesentery. Before the operation the d...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:A study of the indices of iron metabolism in 29 patients with hereditary hemorrhagic telangiectasia revealed a decrease in the level of serum iron, an increase in serum latent and total iron-binding capacity values. The level of blood transferrin studied by radial immunodiffusion was elevated. The level of ferritin in...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：AIM:To assess the prevalence of bacterial overgrowth syndrome (BOS) and its risk factors in patients with inflammatory bowel diseases (IBD). SUBJECTS AND METHODS:The patients from the Novosibirsk IBD registry, who had undergone a hydrogen breath test (HBT) using a Gastro+ device, were examined. RESULTS:In 93 IBD pati...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh201789215-19
更新日期：2017-01-01 00:00:00
abstract：:Altogether 84 patients with duodenal ulcer were examined for a study of mesenchyma function. The blood level of oxyproline, the system of histamine-histaminase-histaminopexic index, and the level of serotonin before and after treatment were studied. The level of IgG, A, M and the amount of T- and B-lymphocytes were de...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：AIM:To detect the most common clinical manifestations of Legionella pneumonia (LP) in immunocompromized patients. SUBJECTS AND METHODS:Clinical manifestations, the results of investigation of bronchoalveolar lavage fluid (BALF) and urine, and the data of lung computed tomography (CT) were studied in patients with bloo...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：:A study was made of the impact of a single intake of nifedipine, intal, sodium thiosulfate and essentiale on respiratory function, the blood content of ionized calcium, total calcium, hydroperoxides, total and non-protein thiol groups, and prostaglandins in bronchial asthma patients. All the drugs exerted an antioxida...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
