[Relationship between the intima-media complex thickness, the risk factors of cardiovascular diseases, and the level of C-reactive protein in gouty patients].

Abstract:

AIM:To estimate a relationship between the intima-media thickness (TIM), cardiovascular risk (CVR) factors, and the level of C-reactive protein (CRP) in gouty patients. SUBJECTS AND METHODS:Eighty-nine patients at an interattack interval were examined. The patients' mean age was 46.0 +/- 11.4 years; the duration of the disease was 5.2 (3.0; 8.9) years. The traditional CVR factors were analyzed. Carotid ultrasound scanning was performed to detect vascular atherosclerotic lesion. The serum CRP concentration was measured by a highly sensitive immunonefelometric assay. RESULTS:According to the TIM, the patients were divided into 2 groups: 1) 37 patients with signs of carotid atherosclerotic lesion (TIM > or = 0.9 mm); 2) 52 patients with a TIM of less than 0.9 mm. The ages at the moment of examination and at the onset of the disease, the duration of the disease, as well as systolic blood pressure, and the risk of myocardial ischemia were greater in Group 1 than those in Group 2. In patients with atherosclerosis, the concentration of CRP was statistically significantly higher than that in patients without this condition. CONCLUSION:By complementing the classical CVR factors, CRP may be a predictor of cardiovascular diseases and their complications in patients with gout at an interattack interval.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Il'ina AE,Varfolomeeva EI,Volkov AV,Mach ES,Aleksandrova EN,Novikov AA,Il'inykh EV,Barskova VG,Nasonov EL

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

45-9

issue

10

eissn

0040-3660

issn

2309-5342

journal_volume

81

pub_type

杂志文章
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    doi:

    authors: Berliner GB

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    doi:

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    doi:

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    更新日期:1994-01-01 00:00:00

  • [Comparative assessment of stress electrocardiographic and echocardiographic tests in the diagnosis of insufficiency of the coronary circulation].

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    doi:

    authors: Kuznetsov VA,Antonov OS,Anmut TP,Riabikov,Baranov II

    更新日期:1988-01-01 00:00:00

  • [The characteristics of the clinical course and treatment of chronic obstructive lung diseases against a background of lymphoproliferative diseases].

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    doi:

    authors: Provotorov VM,Kazabtsov AIu

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  • [Interferon status of patients with non-specific ulcerous colitis and its correction with interferon inducers].

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    doi:

    authors: Maev IV,Grigorian SS,Gadzhieva MG,Ovchinnikova NI,Ospel'nikova TP,Kaziulin AN

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    doi:

    authors: Murataliev TM,Satkynalieva ZT,Kozhanov AS,Tsoĭ SM,Toktosunova AN

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    authors: Savchenko VG,Mikhaĭlova EA,Liubimova LS,Turbina NS,Ustinova EN,Mendeleeva LP,Zakharov GN,Askarov TU

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  • [Plasma heparin precipitate as a source of fibronectin in the treatment of patients with trophic skin lesions].

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    doi:

    authors: Vasil'ev SA,Dzhumabaeva BT,Kolesnikova AS,Ermolin GA,Efremov EE

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  • [Sjögren's syndrome in children].

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  • [Characterization of the genotypes of patients with Gaucher disease type 1 in the Russian Federation].

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    journal_title:Terapevticheskii arkhiv

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    doi:

    authors: Lukina KA,Fevraleva IS,Sysoeva EP,Mamonov BE,Sudarikov AB,Lukina EA

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    pub_type: 杂志文章

    doi:

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    pub_type: 杂志文章

    doi:

    authors: Murashko VV,Alekseeva NV,Strutynskiĭ AV,Torkhovskaia TI,Fortinskaia ES

    更新日期:1986-01-01 00:00:00

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    authors: Rameev VV,Kozlovskaia LV,Bogdanova MV

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    authors: Shvarts VIa,Kuznetsov BG,Frolkov VK,Saakian AG

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