[Characteristics of expression of active oxygen forms by blood cells in patients with chronic bronchitis].

Abstract:

AIM:To study generation of active oxygen forms in the whole blood of patients with chronic bronchitis and correction of the detected disorders. MATERIAL AND METHODS:By means of registration of spontaneous and staphylococcus-induced luminol-dependent chemiluminescence (LDCL) of the whole blood, generation of active oxygen forms in 73 patients with chronic bronchitis (CB) has been studied. RESULTS:By the intensity of luminescence, all the examinees were divided into two groups. In group 1 LDCL was high, in group 2 LDCL was under the control level. Combined treatment of group 1 patients included inhalations of ceruloplasmin antioxidant. Patients of group 2 were administered sodium hypochlorite that possesses prooxidation properties. Compared to conventional treatment, the above two treatments produced marked positive changes in the studied indices and clinical symptoms. CONCLUSION:The method of chemiluminescence registration of the whole blood allows validation of pathogenetic therapy of patients with CB and improves outcomes of the treatment.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Abdrakhmanova LM,Farkhutdinov UR,Farkhutdinov RR

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

45-8

issue

3

eissn

0040-3660

issn

2309-5342

journal_volume

73

pub_type

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