Abstract:
:The 5- and 10-year survival rates of all 114 patients with primary DM were 89 and 81%, respectively. Significantly lower survival rates were noted in the patients receiving late and inadequate therapy. Corticosteroid therapy radically changed the outcome of DM, mainly due to early diagnosis and adequate therapy. A stable remission with preserved working ability was obtained in 40.4% of the patients, a complete cure of DM in 33.3%.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Zhanuzakov MA,Vinogradova OM,Solov'eva APsubject
Has Abstractpub_date
1986-01-01 00:00:00pages
102-5issue
8eissn
0040-3660issn
2309-5342journal_volume
58pub_type
杂志文章abstract::The authors provide the data of many years of study into the morphofunctional status of the gastroduodenal system in 396 patients with peptic ulcer exposed to staged rehabilitation treatment. High medical and economic efficacy of the method is demonstrated. Approaches to the improvement of the results of staged rehabi...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::The content of IgA, IgM, IgG and IgE was measured in 55 male patients with uncomplicated essential hypertension (EH) running a labile course (25 patients) and a stable course (30 patients). Analyzing the material, account was taken of aggravated heredity factor as regards arterial hypertension, established according t...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Ten cases of the pronounced acute nephritic syndrome among patients aged 61 to 82 years are analyzed. In 3 cases, which eventuated in lethal outcome, the diagnosis of nephritis was confirmed morphologically. The features of the course, clinical picture and differential diagnosis of acute nephritides in elderly and sen...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Sixty patients with chronic renal failure (CRF) were studied for the rates of lipid peroxidation (LPO), the state of the antioxidative system (AOS) as well as for the morphofunctional state of biomembranes in renal tubules measured by excretion of low-molecular compounds tested in urine x by means of proton nuclear ma...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::To study humoral antistreptococcal immunity, 29 patients with acute glomerulonephritis (AGN), 211 patients with chronic glomerulonephritis (CGN) and 30 healthy donors were examined. According to EIA, blood sera of the indicated groups demonstrated antibodies (AB) to structural components of Streptococcus--A-polysaccha...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::In up-to-date industrial conditions the new clinical forms of occupational pulmonary diseases occur more and more frequently in addition to the most prevalent dust pathology of the lungs. They occur in workers exposed to industrial aerosols of complex composition, including toxic substances and allergens along with fi...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The authors observed a patient with bronchial asthma who developed acute pulmonary pyodestruction with generalization of the infection, a splenic abscess and drug allergy against prolonged corticosteroid therapy. Diagnostic potentialities, necessary intensive care measures and long-term effects of these complications ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:AIM:A comparative analysis of effectiveness of combined therapy including trimetazidine (preductal) and composition of amino acids (glutamic acid, glycin and cystein) in elderly patients with coronary heart disease and angina of functional class II-III (FC II-III). MATERIALS AND METHODS:60 patients (47 females and 13 ...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-01-01 00:00:00
abstract::Toxic patterns of diphtheria of the fauces in adults are characterized by laryngeal lesions which considerably deteriorate the disease prognosis. The clinical manifestations of diphtheric croup may be unpronounced in such cases and be masked by other severe disease symptoms. If patients with toxic diphtheria develop c...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::The daily Holter ECG monitoring and echocardiography were conducted in 61 men aged on the average 50.5...1.2 years with a diagnosis of stage II essential hypertension. 55.7% of the patients manifested episodes of painless depression of the ST segment. Such parameters as the patients' age, duration and intensity of art...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:AIM:To investigate a potential of a new marker of activity of interstitial pulmonary diseases (IPD)--mucin 3EG5--in monitoring of effectiveness of the antiinflammatory therapy. MATERIALS AND METHODS:Serum mucin antigen 3EG5 (glycolyl-sialylated glycoprotein) was assessed with sandwich immunoassay constructed using a m...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:AIM:To evaluate the efficiency of using a succinate-containing dialysis solution (SCDS) in terminal renal failure patients treated with chronic hemodialysis (CHD). SUBJECTS AND METHODS:Ninety patients from two hemodialysis units took part in the crossover study and were allocated to 2 groups. For 6 months, study group...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,多中心研究,随机对照试验
doi:
更新日期:2013-01-01 00:00:00
abstract::Chronic hepatitis B (CHB) and C (CHC) are one of the leading causes of cirrhosis and liver cancer with over a million of people dying annually from their consequences. In Russia CHB and CHC morbidity and related mortality show an upward trend. As a result of recent breakthroughs in antiviral therapeutics CHC became a ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:10.17116/terarkh201789114-13
更新日期:2017-01-01 00:00:00
abstract::A total of 108 patients with peptic ulcer were entered into the study. Examination of the microcirculation in the eye conjunctiva and microvessels of biopsy specimens of the mucous membrane taken from ulcerous areas revealed that disease relapses were marked by pronounced disorders of the end blood flow. The extent of...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::A double blind randomized cross-over study was conducted to analyze antiarrhythmic activity of the new Soviet drugs allapinin , ethacizine in comparison with mexitil. Altogether 33 patients with ventricular disorders of cardiac rhythm of high gradations after Lown B. were investigated including patients with paroxysma...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1988-01-01 00:00:00
abstract::In the article, we report the causes of pulmonary hemorrhage (PH) according to the literature data and own experience, with an emphasis on patients suffering from rheumatic diseases. Methods of diagnosis and modern approaches to the treatment of PH are analyzed. :В представленной статье на основе данных литературы и ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/00403660.2019.05.000234
更新日期:2019-05-15 00:00:00
abstract:AIM:To study mucous (parietal) gastroduodenal microflora in healthy persons, patients with ulcer and chronic gastritis, to develop diagnostic criteria and classification of gastroduodenal dysbacteriosis. MATERIAL AND METHODS:Biopsy specimens were obtained from gastroduodenal mucosa of 134 patients with ulcer, 36--with...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:AIM:To assess an effect of long-term administration of one combined inhaled drug containing glucocorticosteroids (GCS) and long-acting beta2-agonists (LABA) on patient compliance. MATERIAL AND METHODS:The trial included 47 patients (14 males and 33 females, mean age 48.8 +/- 13.2 years) with bronchial asthma (BA) of d...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Major advances in pharmacology of the 21st century include the development of a new class of drugs, which are low-molecular, chemically synthesized molecules (the so-called "small molecules"), the point of application of which is Janus kinase (Janus kinase, JAK) involved in intracellular cytokine signaling. The review...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:10.26442/00403660.2019.02.000155
更新日期:2019-03-18 00:00:00
abstract:AIM:To study factors of anemia pathogenesis in patients with ulcerative colitis (UC) and Crohn's disease (CD). MATERIAL AND METHODS:A total of 80 patients (56% males and 44% females, mean age 39 +/- 15.8 years) with UC and CD were divided into two groups: group 1--40 patients with anemia, group 2--40 controls free of ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::The authors have analyzed their experience in the diagnosis and treatment of 32 patients with broncholiths-induced obturation of the segmentary and lobar bronchi with subsequent prolonged recurring inflammatory, cirrhotic or suppurative bronchopulmonary processes farther to a site of bronchial obstruction. 37% of the ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:AIM:To determine approaches of the exacerbations treatment of chronic pancreatitis (CP) with IBS (irritable bowel syndrome)-like syndrome. MATERIALS AND METHODS:312 patients with exacerbation of CP were observed and received standard therapy: antispasmodics, enzymes, proton pump inhibitors. 85 (27.2%) patients had no ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/00403660.2020.02.000518
更新日期:2020-04-27 00:00:00
abstract::Based on an analysis of the data pertaining to changes in the level of erythropoietin, chalones and stress hormones in the blood of patients with polycythemia vera after bloodletings and cytapheresis it is concluded that chalones participate in the development of a remission owing to the inhibition of the clone of mut...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:AIM:To validate up-to-date policy of immunosuppressive therapy of patients with aplastic anemia (AA) which has developed either at acute or chronic phase of viral hepatitis. MATERIALS AND METHODS:16 patients with AA detected within 6 months (9 patients) or 12-36 months (7 patients) after acute viral hepatitis received...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:AIM:To clarify the role of differences in the levels of some biologically active substances (BAS) in plasma of patients with resistance to therapy or without it measured before treatment, during treatment and application of plasmapheresis. MATERIALS AND METHODS:Resistance to therapy was assessed clinically and accordi...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Na+/H+ countertransport speed in red cells of insulin-dependent diabetes (IDDM) patients was studied. The rate of Na+/H+ exchange in diabetic erythrocytes did not differ statistically from the rate of such exchange in control erythrocytes. Statistically significant differences in the rates of Na+/H+ exchange in red ce...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Altogether 117 case reports were analyzed and 32 patients with associated gastric or duodenal ulcer and coronary heart disease (CHD) as well as 48 controls suffering from gastric or duodenal ulcer were examined. A relationship was established between the clinical picture and the course of associated ulcer disease and ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::A possibility of life-time fibrinolysis activation with blast cells was studied in 54 patients with different variants of acute leukemia. The study showed that practically in all the variants of acute leukemia the content of fibrinolysis activators in the patients' blood was elevated. Active proteolytic enzymes of non...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::The paper is concerned with a clinical picture of various types of occupational allergic diseases caused by exposure to occupational allergens. In view of a clinical course and pathogenesis of these diseases a set of diagnostic methods was developed, including allergy-oriented examination of patients using skin, endon...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:
更新日期:1988-01-01 00:00:00
abstract::The authors review literature data on porphyrias with combining enzymopathies in heme biosynthesis system, report a case of porphyria cutanea tarda and porphyria variegata registered simultaneously in a male patient clinically and confirmed biochemically. The patient's mother had elevated levels of fecal protoporphyri...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00