Abstract:
AIM:To study mucous (parietal) gastroduodenal microflora in healthy persons, patients with ulcer and chronic gastritis, to develop diagnostic criteria and classification of gastroduodenal dysbacteriosis. MATERIAL AND METHODS:Biopsy specimens were obtained from gastroduodenal mucosa of 134 patients with ulcer, 36--with chronic gastritis and 28 healthy subjects. The mucous microflora agents were isolated microbiologically from biopsy specimens obtained from different compartments of the stomach and duodenum. The spectrum of their enzymatic activity and cytotoxic properties were determined. RESULTS:Gastroduodenal mucous microflora of healthy subjects was represented with 1-2, less often with 3-4 cultures of 12 species, enzymatic activity spectrum of microorganisms was small, cytotoxicity was absent. In ulcer recurrence and exacerbation of chronic gastritis gastroduodenal zone showed dysbacteriosis characterized by overgrowth of mucous microflora (up to 22 species of microorganisms) with a wide spectrum of enzymatic activity and cytotoxic properties. The criteria of dysbacteriosis diagnosis and classification are proposed. CONCLUSION:The role of gastroduodenal mucous microflora in ulcer and gastritis course is specified. New approaches to effective treatment of gastroduodenal diseases may be developed with consideration of dysbacteriosis.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Chernin VV,Bondarenko VM,Chervinets VM,Bazlov SNsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
21-5issue
2eissn
0040-3660issn
2309-5342journal_volume
80pub_type
杂志文章abstract:AIM:To evaluate the efficiency and toxicity of the intensive Burkitt's lymphoma (BL) therapy protocol BL-M-04. SUBJECTS AND METHODS:A total of 70 patients diagnosed with BL, including 45 men and 25 women whose age was 15 to 62 years (median age 31 years), were followed up in 2003 to 2014. Stage I (according to S. Murp...
journal_title:Terapevticheskii arkhiv
pub_type: 社论
doi:10.17116/terarkh20158774-14
更新日期:2015-01-01 00:00:00
abstract::Loop diuretics take the lead in the treatment of patients with symptomatic heart failure. Torasemide is the most effective and safe loop diuretic with the optimal pharmacokinetic profile, the additional properties associated with simultaneous blockade of the renin-angiotensin-aldosterone system and with the antiadrene...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::In 50 patients with gastric ulcer indices of oxygen tension (pO2) levels were investigated in correlation with the concentration of prostaglandins (E and F2 alpha), prostacyclin, thromboxane as well as with values of transmucous difference of potentials in different parts of the gastric mucosa, they were compared with...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh201789162-71
更新日期:2017-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
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更新日期:2017-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Arteparon was locally used in 87 patients after reconstructive surgery on the joints. Arteparon administration was conducted 2 weeks following corrective operations: arthrotomy, allo- and autoplasty, replantation of the limb segments, arthroplasty, one-pole endoprosthesis. The drug was introduced into the hip, knee, a...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2007-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh2014861248-52
更新日期:2014-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::A therapeutic effect of prospidine, a Soviet antitumor drug, was studied on the basis of clinicoimmunological correlations in 74 patients with proved rheumatoid arthritis (RA) who were resistant to well known basic drugs. It was administered parenterally and intraarticularly according to the methods developed by the a...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:1986-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
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journal_title:Terapevticheskii arkhiv
pub_type: 社论
doi:
更新日期:2010-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
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更新日期:2015-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:1986-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00