[Levels of biologically active substances in the blood of patients resistant and nonresistant to antihypertensive therapy].

Abstract:

AIM:To clarify the role of differences in the levels of some biologically active substances (BAS) in plasma of patients with resistance to therapy or without it measured before treatment, during treatment and application of plasmapheresis. MATERIALS AND METHODS:Resistance to therapy was assessed clinically and according to 24-h monitoring in 35 patients aged 35-56 years with essential hypertension (n = 19), related to chronic pyelonephritis (n = 13) and glomerulonephritis (n = 3). Plasma BAS were studied by radio- and enzyme immunoassays. RESULTS:Blood pressure monitoring provided more precise determination of the treatment responders than clinical tests. Initially, responders to therapy had higher level of endothelin-1 and low of hydrocortisone. CONCLUSION:Responders to antihypertensive therapy were distinguished by a significant decrease of plasma aldosterone within a year vs aldosterone levels before the treatment. Nonresponders had no significant decrease of plasma aldosterone. No other marked differences in plasma BAS between the responders and nonresponders to antihypertensive treatment were found.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Tabak'ian EA,Dmitriev VV,Masenko VP,Kukharchuk VV

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

62-7

issue

3

eissn

0040-3660

issn

2309-5342

journal_volume

71

pub_type

杂志文章
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    authors: Dvoretsiiĭ LI,Didkovskiĭ NA,Charlyev G

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    authors: Korchmaru IF,Iakovleva IA

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    authors: Shutov AM,Edigarov OM,Mastykov VE

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    doi:

    authors: Poliakova ND,Spiridonov AA

    更新日期:1996-01-01 00:00:00

  • [Arthrotec treatment of rheumatoid arthritis].

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    doi:

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  • [Viable myocardium: comparative evaluation of surgical and pharmacological treatment of patients with ischemic heart disease, post-infarct cardiosclerosis and chronic cardiac failure].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Saidova MA,Belenkov IuN,Akchurin RS,Sergienko VB,Khodareva EN,Kostrova VV

    更新日期:2002-01-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Idel'son LI,Pogorel'skaia EP,Il'in GP,Gorodetskiĭ VM

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  • [Chronic cerebral circulatory insufficiency: A clinical case report].

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    doi:

    authors: Urazgil'deeva SA,Shatalina LV,Gurevich VS

    更新日期:1999-01-01 00:00:00

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    doi:

    authors: Virsaladze KS

    更新日期:1987-01-01 00:00:00

  • [Chronic cardiac failure in the XXI century].

    abstract::Wide clinical application of modern prophylactic, diagnostic and therapeutic methods has significantly improved clinical outcomes of cardiovascular disorders. However, much progress is not seen in survival of patients with chronic cardiac failure (CCF). Three possible causes of this situation are analysed: absence of ...

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    pub_type: 杂志文章,评审

    doi:

    authors: Tereshchenko SN,Zhirov IV

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  • [Diagnosis of coronary artery lesions during the exercise test according to electrocardiotopographic data in patients with ischemic heart disease].

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    authors: Ianovskiĭ GV,Terzov AI,Belonozhko AG

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    更新日期:2020-04-27 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Bariakh EA,Zvonkov EE,Kremenetskaia AM,Kravchenko SK,Magomedova AU,Obukhova TN,Samoĭlova RS,Vorob'ev IA,Kaplanskaia IB,Moiseeva TN,Zybunova EE,Lorie IuIu,Chernova NG,Mar'in DS,Egorova EK,Krasil'nikova BB,Gabeeva NG,Voro

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  • [Autonomic and emotional disorders in chronic obstructive bronchitis].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kulakov IuA

    更新日期:1985-01-01 00:00:00

  • [Ophthalmologic manifestation of granulomatosis with polyangiitis (Wegener's granulomatosis)].

    abstract::Granulomatosis with polyangiitis (GPA), formerly earlier known as Wegener's granulomatosis, is primary system necrotizing vasculitis of small and medium-sized vessels, which is characterized by the formation of foci of granulomatous inflammation. One of the target organs in GPA is the organ of vision. Its affection ma...

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    doi:

    authors: Goloeva RG,Alekberova ZS,Guseva IA,Krylov MIu

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  • [Clinical considerations in the treatment of atrial fibrillation (in thyrotoxicosis patients)].

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    doi:

    authors: Kedrov AA,Somova LV

    更新日期:1984-01-01 00:00:00

  • [Estimation of podocyte dysfunction by nephrinuria severity in proteinuric forms of chronic glomerulonephritis].

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    authors: Chebotareva NV,Bobkova IN,Kozlovskaia LV,Tsopanova ZG

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  • A new look at dietary fibers in metabolic syndrome.

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  • [A clinical course of coronary heart disease after pacemaker implantation and optimization of the pacing regime].

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    更新日期:2004-01-01 00:00:00

  • [The epidemiology of the risk factors for cardiovascular diseases and their combination among the male population in the cities of different regions of the CIS Nations and Baltic states. A cooperative study].

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    doi:

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    更新日期:1993-01-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Degtiareva II,Solodova EV

    更新日期:1984-01-01 00:00:00

  • [Hematosalivary mechanisms of regulation in rheumatoid arthritis].

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    pub_type: 杂志文章

    doi:

    authors: Ulanova EA,Grigor'ev IV,Novikova IA

    更新日期:2001-01-01 00:00:00

  • [Protection of reproduction function in women with Hodgkin's disease in the course of polychemotherapy].

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    pub_type: 杂志文章

    doi:

    authors: Ignashina EV,Rasstrigin NA,Margolin OV,Pivnik AV,Shilin DE

    更新日期:1999-01-01 00:00:00

  • [Effect of bortezomib on the efficiency of hematopoietic stem cell mobilization in patients with multiple myeloma].

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    doi:

    authors: Pokrovskaia OS,Mendeleeva LP,Urnova ES,Gaponova TV,Gal'tseva IV,Kuz'mina LA,Akhundova FM,Kalinin NN,Gretsov EM,Parovichnikova EN,Savchenko VG

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    doi:

    authors: Chumak GE,Udal'tsov BB,Iakovlev VA,Zhogolev SD,Vishniakova LA

    更新日期:1991-01-01 00:00:00

  • [The correlations of lipid peroxidation, antioxidant protection and microrheological disorders in the development of IHD].

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    pub_type: 杂志文章

    doi:

    authors: Zakirova AN

    更新日期:1996-01-01 00:00:00