[The evaluation of the efficacy of azithromycin and pyrimethamine used alone or in combination in the treatment of an experimental infection in mice by Toxoplasma gondii].

Abstract:

:The efficacy of azithromycin and pyrimethamine in experimental infection of mice with Toxoplasma gondii was tested. Daily dosages of 200 mg/kg and 12.5 mg/kg, respectively, were given orally over a period of ten days. The medications were administered in combination or separately. The combined use of the drugs yielded better results, and a similar investigation using a cystogenic strain of the parasite will be conducted in a future study.

journal_name

Rev Soc Bras Med Trop

authors

Braz LM,Di Pietro AO,Amato Neto V,França FO

doi

10.1590/s0037-86821999000400011

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

401-3

issue

4

eissn

0037-8682

issn

1678-9849

journal_volume

32

pub_type

杂志文章
  • [Disseminated pulmonary adiaspiromycosis. A case report].

    abstract::A case of thoracoscopic lung biopsy proven diffuse human adiaspiromycosis is reported. The patient, a 26-year-old male farm worker presented with a three-week history of fever, sweating, dyspnea and unproductive cough. Radiographic findings were those of granulomatous pulmonary interstitial disease. Treated with ketoc...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章,评审

    doi:10.1590/s0037-86821997000500009

    authors: dos Santos VM,Santana JH,Adad SJ,Lopes GP,Fatureto Mda C

    更新日期:1997-09-01 00:00:00

  • Vaccination of C57BL/10 mice against cutaneous Leishmaniasis using killed promastigotes of different strains and species of Leishmania.

    abstract::Antigenic extracts from five Leishmania stocks were used to vaccinate C57BL/10 mice. The Leishvacin(R) and PH8 monovalent vaccine yielded the highest IFN-gamma levels in the supernatants of spleen cell culture from vaccinated animals. Each single strain immunized group showed evidence of protective immunity six months...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822002000200001

    authors: Mayrink W,Santos GC,Toledo Vde P,Guimaraes TM,Machado-Coelho GL,Genaro O,da Costa CA

    更新日期:2002-03-01 00:00:00

  • Research regarding anti-PGL-I antibodies by ELISA in wild armadillos from Brazil.

    abstract::Armadillos have been involved in leprosy transmission and are considered a source of Mycobacterium leprae in numerous reports. Clinicians from certain areas of the USA consider contact with armadillos a risk factor for leprosy. However, there is a challenge associated with the role of wild armadillos perpetuating huma...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822008000700015

    authors: Deps PD,Antunes JM,Faria C,Bührer-Sékula S,Camargo ZP,Opromola DV,Tomimori J

    更新日期:2008-01-01 00:00:00

  • [About the use of "Maria" bio-sensors in the activities of epidemiological surveillance against Chagas' disease in the North of Minas Gerais State].

    abstract::Eight hundred and sixty six bio-sensors for the passive detection of triatomine bugs, were tried in intra-domiciles of thirteen municipalities of an endemic area of Triatoma sordida in the North of Minas Gerais State, Brazil. This species is nowadays the most captured in Brazil and mainly in the above region. The sens...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822005000500002

    authors: Dias JC,Vieira Ede P,Tadashi H,Azeredo BV

    更新日期:2005-09-01 00:00:00

  • [Strongyloidiasis in patients with pemphigus foliaceus].

    abstract::In 30 patients with foliaceus pemphigus the frequency of strongyloidiasis was 40%, by three Baermann-Moraes examination. In the "Hospital do Pênfigo", for patients with pemphigus of Uberaba, the frequencies of strongyloidiasis in the employees (n = 14) and students (n = 47), of the annexed nursery, also were high, res...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821991000300004

    authors: Tavares-Neto J,Alves DB,Franciscon e Carlos JU,Serrano RS

    更新日期:1991-07-01 00:00:00

  • [Influence of specific treatment of intestinal parasites and schistosomiasis on prevalence in students in Barra de Santo Antônio, AL].

    abstract::From a total of 1,020 students examined, 983 (92%) showed positive results for at least one species of parasite. Six months after treatment, a sample of 383 students (37.5%) was reevaluated and 347 (90.6%) presented positive results. There was no significant change in prevalence before and after treatment, although th...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822003000500015

    authors: Fontes G,Oliveira KK,Oliveira AK,da Rocha EM

    更新日期:2003-09-01 00:00:00

  • Giardia duodenalis: genotypic comparison between a human and a canine isolates.

    abstract:INTRODUCTION:Evidence suggests that giardiasis is a zoonotic disease. The present work aimed to evaluate the genetic identity of Giardia duodenalis isolated from human and dog fecal samples from Belo Horizonte. METHODS:Human and dog fecal samples were cultured for isolation of G. duodenalis. To determine the genotype ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822011000400021

    authors: Gomes KB,Fernandes AP,Menezes A,Amorim Júnior R,Silva EF,Rocha MO

    更新日期:2011-07-01 00:00:00

  • First serologic evidence of human hantavirus infection in Alagoas State in Northeastern Brazil.

    abstract:INTRODUCTION:Hantavirus cardiopulmonary syndrome (HCPS) is rare in Northeastern Brazil. METHODS:Prospective surveillance was conducted over a two-year period in Alagoas State, Northeastern Brazil. The prevalence of anti-hantavirus N-antigen IgM and IgG in human serum samples was determined by enzyme-linked immunosorbe...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0117-2017

    authors: Santos-Júnior JAD,Santos FMD,Barros PA,Medeiros NPT,Sabino-Santos Júnior G,Lima MC,Figueiredo LTM,Borges AA

    更新日期:2017-11-01 00:00:00

  • Presence of anti-Toxoplasma antibodies in humans and their cats in the urban zone of Guadalajara.

    abstract::Cats are the definitive hosts of Toxoplasma gondii. Infected cats excrete oocysts in their feces, infecting humans and other animals. The objective of the present study was to determine the presence of anti-Toxoplasma antibodies in cat owners and their pets, and determine if there was a relationship between Toxoplasma...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821999000500003

    authors: Galván Ramírez ML,Sánchez Vargas G,Vielma Sandoval M,Soto Mancilla JL

    更新日期:1999-09-01 00:00:00

  • Hepatitis B virus surface antigen (HBsAg) and antibody (anti-HBs) forming immune complexes in fulminant hepatitis.

    abstract::This paper reports an unusual pattern of serological HBV markers and the presence of HBsAg/anti-HBs immune complexes in serum samples from two patients with fulminant hepatitis from the Brazilian Western Amazon Basin. The diagnosis was made by both serologic tests and demonstration of antigen/antibody complexes by tra...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821999000300012

    authors: Soares MC,Bensabath G,Cartágenes PR,Alves MM,Silveira FA,Linhares AC

    更新日期:1999-05-01 00:00:00

  • Evaluation of constitutive and inducible resistance to clindamycin in clinical samples of Staphylococcus aureus from a tertiary hospital.

    abstract:INTRODUCTION:Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become common in hospitals and the community environment, and this wide resistance has limited patient treatment. Clindamycin (CL) represents an important alternative therapy for infections caused by S. aureus. Antimicrobial susce...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0140-2014

    authors: Bottega A,Rodrigues Mde A,Carvalho FA,Wagner TF,Leal IA,Santos SO,Rampelotto RF,Hörner R

    更新日期:2014-09-01 00:00:00

  • Local and systemic effects caused by Crotalus durissus terrificus, Crotalus durissus collilineatus, and Crotalus durissus cascavella snake venoms in swiss mice.

    abstract:INTRODUCTION:Crotalus envenomations cause serious complications and can be fatal without appropriate treatment. Venom isoforms present and inter/intraspecific variations in the venom composition can result in different symptoms presented by bites by snakes from the same species but from different geographical regions. ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0526-2018

    authors: Carvalho LH,Teixeira LF,Zaqueo KD,Bastos JF,Nery NM,Setúbal SS,Pontes AS,Butzke D,Cavalcante W,Gallacci M,Fernandes CFC,Stabeli RG,Soares AM,Zuliani JP

    更新日期:2019-09-05 00:00:00

  • Snail transmitters of schistosomiasis and other mollusks of medical and economic importance at the Simplício Queda Única Hydroelectric Plant, Southeast Brazil.

    abstract:INTRODUCTION:This paper presents the results of an extensive survey of freshwater mollusks in the Simplício Queda Única Hydroelectric Development area, Southeast Brazil. METHODS:Mollusks were collected between 2008 and 2013. All specimens were examined for the presence of larval trematodes. RESULTS:In total, 12,507 s...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0334-2017

    authors: Fernandez MA,Silva EFD,Esteves RA,Thiengo SC

    更新日期:2018-09-01 00:00:00

  • Evaluation of the six-minute walk test in patients with chronic heart failure associated with Chagas' disease and systemic arterial hypertension.

    abstract:INTRODUCTION:To evaluate physical capacity as determined by the six-minute walk test (6MWT) in patients with chronic heart failure due to Chagas' disease associated with systemic arterial hypertension (Chagas-SAH). METHODS:A total of 98 patients routinely followed at the Cardiomyopathy Outpatient Service were recruite...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822010000400014

    authors: Dourado KC,Bestetti RB,Cardinalli-Neto A,Cordeiro JA

    更新日期:2010-07-01 00:00:00

  • Twenty-eight years of Aedes albopictus in Brazil: a rationale to maintain active entomological and epidemiological surveillance.

    abstract:INTRODUCTION:Aedes albopictus was first detected in Brazil in 1986. This mosquito species presents a major threat to public health because Brazilian populations have shown substantial vector competence for arboviruses such as dengue and chikungunya. METHODS:We updated the records of Ae. albopictus in several States of...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0155-2014

    authors: Pancetti FG,Honório NA,Urbinatti PR,Lima-Camara TN

    更新日期:2015-01-01 00:00:00

  • [Concurrent leishmaniasis and human immunodeficiency virus (HIV) infection: a study of four cases].

    abstract::Few cases of concurrent leishmaniasis and HIV infection have been reported in Brazil, despite both infections being in expansion. Two cases of visceral leishmaniasis and two cases of mucocutaneous leishmaniasis are discussed. Disseminated skin and oral lesions were found in the patients with the cutaneous form of the ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:

    authors: Borges AS,Machado AA,Ferreira MS,de Castro Figueiredo JF,Silva GF,Cimerman S,Bacha HA,Teixeira MC

    更新日期:1999-11-01 00:00:00

  • Does my patient have chronic Chagas disease? Development and temporal validation of a diagnostic risk score.

    abstract:INTRODUCTION:With the globalization of Chagas disease, unexperienced health care providers may have difficulties in identifying which patients should be examined for this condition. This study aimed to develop and validate a diagnostic clinical prediction model for chronic Chagas disease. METHODS:This diagnostic cohor...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0196-2016

    authors: Brasil PE,Xavier SS,Holanda MT,Hasslocher-Moreno AM,Braga JU

    更新日期:2016-05-01 00:00:00

  • Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin.

    abstract:INTRODUCTION:This study confirmed the absence of natural infection with Xenotropic murine leukemia virus-related virus (XMRV) or XMRV-related disease in human populations of the Brazilian Amazon basin. We demonstrated that 803 individuals of both sexes, who were residents of Belem in the Brazilian State of Pará, were n...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0075-2014

    authors: Gomes ST,Imbiriba L,Burbano RR,Silva AL,Feitosa RN,Cayres-Vallinoto IM,Ishak Mde O,Ishak R,Vallinoto AC

    更新日期:2014-05-01 00:00:00

  • Characterization of biofilm formation, antimicrobial resistance, and staphylococcal cassette chromosome mec analysis of methicillin resistant Staphylococcus hominis from blood cultures of children.

    abstract:INTRODUCTION::Methicillin resistant Staphylococcus hominis (MRSHo) has been recognized as an important human pathogen, particularly in immunocompromised patients. METHODS::A total of 19 S. hominis isolates were collected from children at the Children's Medical Centre, Tehran, Iran, from March 2012 to February 2013. MR...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0384-2016

    authors: Soroush S,Jabalameli F,Taherikalani M,Eslampour MA,Beigverdi R,Emaneini M

    更新日期:2017-05-01 00:00:00

  • Dengue in Brazil and Colombia: a study of knowledge, attitudes, and practices.

    abstract::Introduction This study was conducted in Brazil and Colombia,where dengue is endemic and vector control programs use chemical insecticides. Methods We identified knowledge, attitudes, and practices about dengue and determined the infestation levels of Aedes aegypti in one Brazilian and four Colombian communities. Resu...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0048-2014

    authors: Santos SL,Parra-Henao G,Silva MB,Augusto LG

    更新日期:2014-11-01 00:00:00

  • Comparison of methodologies for detecting Trypanosoma cruzi parasites by microscopic observation of microhematocrit capillary tubes.

    abstract:INTRODUCTION:The microscopic examination of microhematocrit tubes (mHCT) has been proposed as the gold standard for acute and congenital Chagas disease diagnosis. We compared different mHCT methodologies detecting T. cruzi parasites in the blood. METHODS:The rotating method, water mount, and immersion oil methods were...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0505-2018

    authors: Vera-Ku M,Meza-González G,Carlier Y,Truyens C,Gamboa-León R

    更新日期:2019-06-27 00:00:00

  • [Malnutrition and hypovitaminosis A in AIDS patients].

    abstract::Anthropometric measurements and biochemical determinations were performed on HIV-infected individuals and on patients with AIDS from the Ribeirão Preto region, SP, Brazil, in order to evaluate their nutritional and vitamin A status. Plasma retinol was measured by HPLC, and hepatic vitamin A stores were evaluated by th...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821999000200001

    authors: Silveira SA,Figueiredo JF,Jordão Júnior A,de Unamuno Mdo R,Rodrigues M deL,Vannucchi H

    更新日期:1999-03-01 00:00:00

  • Bacterial meningitis and living conditions.

    abstract:INTRODUCTION:Bacterial meningitis has great social relevance due to its ability to produce sequelae and cause death. It is most frequently found in developing countries, especially among children. Meningococcal meningitis occurs at a high frequency in populations with poor living conditions. This study describes the te...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822012000300009

    authors: Souza SF,Costa Mda C,Paim JS,Natividade MS,Pereira SM,Andrade AM,Teixeira MG

    更新日期:2012-06-01 00:00:00

  • American cutaneous leishmaniasis in a northeast Brazilian city: clinical and epidemiological features.

    abstract:INTRODUCTION:This study characterized the clinico-epidemiological profile of American cutaneous leishmaniasis (ACL) cases in Barbalha, Ceará State, Brazil. METHODS:Medical records of 363 patients visiting Federal University of Cariri between 2009 and 2014 were analyzed. RESULTS:ACL was more prevalent in men with low ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0504-2017

    authors: Grangeiro Júnior CRP,Pimentel JVC,Teixeira Júnior AG,Jesus AF,Galvão TCF,Souza LAA,Gadelha MDSV,Damasceno KS,Rolim Neto ML,Lima MAP,Nascimento VBD,Silva CGLD

    更新日期:2018-11-01 00:00:00

  • Therapeutic drug monitoring of benznidazole and nifurtimox: a systematic review and quality assessment of published clinical practice guidelines.

    abstract::The pharmacological management of adults with chronic-phase Chagas disease is challenging despite it being the recent focus of extensive research. One of the challenges in the current clinical practice guidelines (CPGs) landscape is the existence of non-evidence-based recommendations for the use of laboratory tests in...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章,评审

    doi:10.1590/0037-8682-0399-2016

    authors: Olivera MJ,Fory JA,Olivera AJ

    更新日期:2017-11-01 00:00:00

  • Risk factors associated with Leishmania exposure among dogs in a rural area of Ilha Solteira, SP, Brazil.

    abstract:INTRODUCTION:We sought to determine risk factors (RFs) associated with the presence of antibodies against Leishmania in dogs from a rural area of Ilha Solteira, SP, Brazil. METHODS:Serum samples were collected from 250 dogs and tested using indirect enzyme-linked immunosorbent assay (ELISA) and indirect immunofluoresc...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/0037-8682-0059-2020

    authors: Spada JCP,Silva DTD,Alves ML,Cárdenas NC,Inlamea OF,Faria GA,Ferreira AG,Silva HR,Oliveira TMFS,Buzetti WAS

    更新日期:2020-09-11 00:00:00

  • The result patterns of ML Flow and ELISA (PGL-I) serologic tests in leprosy-endemic and non-endemic areas.

    abstract::ML Flow and anti-PGL-I ELISA are serological tests that detect IgM antibodies against the phenolic glycolipid I (PGL-I), specific to Mycobacterium leprae. To evaluate the outcomes of ML Flow and ELISA (PGL-I) serological tests in leprosy-endemic areas in comparison to non-endemic ones, a total of 351 volunteers from B...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章,多中心研究

    doi:10.1590/s0037-86822008000700005

    authors: Silva RC,Lyon S,Araos R,Lyon AC,Grossi MA,Lyon SH,Penido RA,Bührer-Sékula S,Antunes CM

    更新日期:2008-01-01 00:00:00

  • [Characterization of multidrug-resistant tuberculosis during pregnancy in Campinas, State of São Paulo, Brazil, from 1995 to 2007].

    abstract:INTRODUCTION:There was a follow-up of pregnant women treated for multidrug-resistance tuberculosis (MDR-TB) during pregnancy in Campinas, State of São Paulo, Brazil, from 1995 to 2007. METHODS:In a retrospective study, patients with tuberculosis who were resistant to at least isoniazid and rifampicin and had pregnancy...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:

    authors: Oliveira HB,Mateus SH

    更新日期:2011-10-01 00:00:00

  • [An evaluation of the efficacy of the CSF method for diagnosing intestinal helminthiases].

    abstract::The recently proposed CSF method for diagnosing intestinal helminthiases was compared with the other methods (direct; Faust et al.; spontaneous sedimentation in water; and Kato-Katz) that are routinely for this purpose. The CSF method performed satisfactorily, thus showing that this technique can be adopted for use in...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86822007000300025

    authors: Alarcón RS,Amato Neto V,Gakiya E,Bezerra RC

    更新日期:2007-05-01 00:00:00

  • Family occurrence of schistosomal hepatosplenomegaly and maternal effect.

    abstract::In this paper we present a study of members of 265 nuclear families, aged six or more. This study is based of family heredograms, and takes into account the clinical form of schistosomiasis observed before treatment with oxamniquine. The probability of occurrence of two or more cases of hepatosplenomegaly is low, notw...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章

    doi:10.1590/s0037-86821989000100003

    authors: Tavares-Neto J,Prata A

    更新日期:1989-01-01 00:00:00