[Malnutrition and hypovitaminosis A in AIDS patients].

Abstract:

:Anthropometric measurements and biochemical determinations were performed on HIV-infected individuals and on patients with AIDS from the Ribeirão Preto region, SP, Brazil, in order to evaluate their nutritional and vitamin A status. Plasma retinol was measured by HPLC, and hepatic vitamin A stores were evaluated by the relative dose response (RDR) test. Patients with AIDS presented significant undernutrition, with more marked alterations in the body fat compartment and a relative preservation of the parameters related to muscle mass (pattern of malnutrition predominantly of the marasmus type). Plasma retinol values below 1.05 mumol/L were observed in 25% of the patients with AIDS and in 17.3% of HIV-infected patients and RDR values indicating low body stores of vitamin A were detected in 28% of the subjects. There was no correlation between serum retinol levels and CD4 lymphocyte counts, clinical diagnosis of AIDS, low BMI or AFI. On the other hand, hypovitaminosis A status was associated with low BMI.

journal_name

Rev Soc Bras Med Trop

authors

Silveira SA,Figueiredo JF,Jordão Júnior A,de Unamuno Mdo R,Rodrigues M deL,Vannucchi H

doi

10.1590/s0037-86821999000200001

subject

Has Abstract

pub_date

1999-03-01 00:00:00

pages

119-24

issue

2

eissn

0037-8682

issn

1678-9849

journal_volume

32

pub_type

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