Seroprevalence of hepatitis B virus infection and seroconvertion to anti-HBsAg in laboratory staff in Goiânia, Goiás.

Abstract:

:Were analyzed 648 serum samples from laboratory staff in Goiânia, Goiás aiming detection of three serological markers of HBV: HBsAg, anti-HBsAg and anti-HBcAg. The HBsAg and anti-HBcAg positive samples were also analyzed for HBeAg, anti-HBeAg and anti-HBcAgIgM markers. HBV infection rate of 24.1% was observed and, from them, 0.7% were positive for HBsAg. Viral DNA was detected by PCR in two HBsAg positive samples. A vaccination index of 74.5% and a global index of 89.9% of serological response to vaccination were observed. The direct work with biological fluids as well as cleaning workers represented significant risks for acquisition of HBV infection. The data from the present study showed an increase of the vaccination index among laboratory staff but the rates of HBV infection did not change through the years in the region.

journal_name

Rev Soc Bras Med Trop

authors

Silva PA,Fiaccadori FS,Borges AM,Silva SA,Daher RR,Martins RM,Cardoso Dd

doi

10.1590/s0037-86822005000200005

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

153-6

issue

2

eissn

0037-8682

issn

1678-9849

pii

S0037-86822005000200005

journal_volume

38

pub_type

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