First serologic evidence of human hantavirus infection in Alagoas State in Northeastern Brazil.

Abstract:

INTRODUCTION:Hantavirus cardiopulmonary syndrome (HCPS) is rare in Northeastern Brazil. METHODS:Prospective surveillance was conducted over a two-year period in Alagoas State, Northeastern Brazil. The prevalence of anti-hantavirus N-antigen IgM and IgG in human serum samples was determined by enzyme-linked immunosorbent assay testing. RESULTS:High avidity IgG was found in nine of 476 serum samples tested (from 102 patients with clinical manifestations compatible with HCPS, 124 patients with leptospirosis, and 250 healthy rural workers). CONCLUSIONS:Serologic evidence of past hantavirus infection in residents of Alagoas State indicates that hantaviruses are present in northeastern Brazil, even in areas silent for HCPS.

journal_name

Rev Soc Bras Med Trop

authors

Santos-Júnior JAD,Santos FMD,Barros PA,Medeiros NPT,Sabino-Santos Júnior G,Lima MC,Figueiredo LTM,Borges AA

doi

10.1590/0037-8682-0117-2017

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

819-823

issue

6

eissn

0037-8682

issn

1678-9849

pii

S0037-86822017000600819

journal_volume

50

pub_type

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