[Acute phase of Chagas disease in the Brazilian Amazon region: study of 233 cases from Pará, Amapá and Maranhão observed between 1988 and 2005].


:Two hundred and thirty-three cases of the acute phase of Chagas disease, from Pará, Amapá and Maranhão, were observed between 1988 and 2005. One hundred and sixty were studied retrospectively from 1988 to 2002 and seventy-three were prospectively followed up from 2003 to 2005. Among the cases studied, 78.5% (183/233) formed part of outbreaks, probably due to oral transmission (affecting a mean of 4 individuals), and 21.5% (50/233) were isolated cases. Cases were taken to be acute if they presented positive direct parasitological tests (fresh blood, thick drop or Quantitative Buffy Coat, QBC) and/or positive anti Trypanosoma cruzi IgM. Xenodiagnosis was also performed on 224 patients and blood culturing on 213. All the patients had clinical and epidemiological evaluations. The most frequent clinical manifestations were fever (100%), headache (92.3%), myalgia (84.1%), pallor (67%), dyspnea (58.4%), swelling of the legs (57.9%), facial edema (57.5%), abdominal pain (44.3%), myocarditis (39.9%) and exanthema (27%). The electrocardiogram showed abnormalities of ventricular repolarization in 38.5%, low QRS voltage in 15.4%, left-axis deviation in 11.5%, ventricular ectopic beats in 5.8%, bradycardia in 5.8%, tachycardia in 5.8%, right branch block in 4.8% and atrial fibrillation in 4.8%. The most frequently observed abnormality on the echocardiogram was pericardial effusion, in 46.2% of the cases. Thirteen (5.6%) patients died: ten (76.9%) of them due to cardiovascular involvement, two due to digestive complications and one due to indeterminate causes.


Rev Soc Bras Med Trop


Pinto AY,Valente SA,Valente Vda C,Ferreira Junior AG,Coura JR




Has Abstract


2008-11-01 00:00:00














  • Mycobacterium tuberculosis spoligotypes and drug-resistant characterization from Beira compared to genotypes circulating in Mozambique.

    abstract:INTRODUCTION:Mozambique is one of three countries with high prevalence of tuberculosis (TB), TB/human immunodeficiency virus coinfection, and multidrug-resistant TB. We aimed to describe Mycobacterium tuberculosis spoligotypes circulating among drug resistant (DR) strains from Beira, Mozambique comparing them with geno...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Anselmo LMP,Conceição EC,Namburete E,Feliciano C,Spindola S,Sola C,Bollela VR

    更新日期:2019-11-25 00:00:00

  • The topical treatment of old world cutaneous leishmaniasis with gentian violet along with cryotherapy: a pilot single-blind randomized controlled clinical trial.

    abstract:INTRODUCTION:The promising non-clinical antileishmanial effects of gentian violet (GV) encouraged us to evaluate the additive effect of GV on cryotherapy. METHODS:For 8 weeks, 59/161 cutaneous leishmaniasis patients/lesions underwent cryotherapy alone (group 1) or cryotherapy accompanied by 1% GV application (group 2)...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章,随机对照试验


    authors: Sepaskhah M,Behdad K,Bagheri Z

    更新日期:2019-04-11 00:00:00

  • Malaria outbreaks in a non-endemic area of Brazil, 2005.

    abstract::In March 2005, a resident of the municipality of Monte Alegre de Minas, State of Minas Gerais, without any history of traveling to endemic areas for malaria, was diagnosed with Plasmodium vivax infection and local mosquito-borne transmission was suspected. The epidemiological investigation identified another 10 cases ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Limongi JE,Chaves KM,Paula MB,Costa FC,Silva Ade A,Lopes Ide S,Pajuaba Neto Ade A,Sales JM,Rodrigues F,Resende MA,Ferreira MS

    更新日期:2008-05-01 00:00:00

  • [Evaluation of the performance of immunological parameters as indicators for clinical progression of chronic HTLV-1 infection].

    abstract::This study evaluated the performance of single and combined laboratory parameters, B-lymphocyte percentages (%LB), T/B cell ratio and %CD8+HLA-DR+/CD8+, to differentiate asymptomatic cases (AS) from HAM/TSP patients (HT) within a population of HTLV-1 seropositive cases. Percentage indices demonstrated that each parame...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Coelho-dos-Reis JG,Rocha RD,Brito-Melo GE,Ribas JG,Carneiro-Proietti AB,Catalan-Soares B,Barbosa-Stancioli EF,Grupo Interdisciplinar de Pesquisas em HTLV.,Martins-Filho OA

    更新日期:2007-01-01 00:00:00

  • Angiostrongylus costaricensis and the intermediate hosts: observations on elimination of L3 in the mucus and inoculation of L1 through the tegument of mollucs.

    abstract::Human accidental infection with Angiostrongylus costaricensis may result in abdominal disease of varied severity. Slugs from the Veronicellidae family are the main intermediate hosts for this parasitic nematode of rodents. Phyllocaulis variegatus, Phyllocaulis soleiformis and Phyllocaulis boraceiensis were experimenta...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Bonetti VC,Graeff-Teixeira C

    更新日期:1998-05-01 00:00:00

  • Prevalence of enterotoxin-encoding genes and antimicrobial resistance in coagulase-negative and coagulase-positive Staphylococcus isolates from black pudding.

    abstract:INTRODUCTION:Staphylococcal species are pathogens that are responsible for outbreaks of foodborne diseases. The aim of this study was to investigate the prevalence of enterotoxin-genes and the antimicrobial resistance profile in staphylococcus coagulase-negative (CoNS) and coagulasepositive (CoPS) isolates from black p...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Moura TM,Campos FS,d'Azevedo PA,Van Der Sand ST,Franco AC,Frazzon J,Frazzon AP

    更新日期:2012-10-01 00:00:00

  • Larvicidal efficiency of the mushroom Amanitamuscaria (Agaricales, Amanitaceae) against the mosquito Culexquinquefasciatus (Diptera, Culicidae).

    abstract:INTRODUCTION:We report the larvicidal activity of two formulations from Amanita muscariaagainst Culex quinquefasciatus, as well as the viability of the aqueous extract after storage. METHODS The larvicidal activity of aqueous extract and powder from A. muscaria, and the viability of the aqueous extract after storage, w...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Cárcamo MC,Carapeto LP,Duarte JP,Bernardi E,Ribeiro PB

    更新日期:2016-02-01 00:00:00

  • Corretion.

    abstract::[This corrects the article doi: 10.1590/0037-8682-0243-2015] [This corrects the article doi: 10.1590/0037-8682-0454-2015]. ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 已发布勘误



    更新日期:2016-09-01 00:00:00

  • Major environmental and socioeconomic determinants of cutaneous leishmaniasis in Brazil - a systematic literature review.

    abstract::Cutaneous leishmaniasis (CL) is a zoonotic disease with complex transmission cycle. Some environmental and socioeconomic factors are known to be the major determinants of the transmission process, which are involved in configuring the spatiotemporal patterns and thus can be delimiting. However, the relevance of these ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Buzanovsky LP,Sanchez-Vazquez MJ,Maia-Elkhoury ANS,Werneck GL

    更新日期:2020-01-01 00:00:00

  • Molecular identification of the agent of Q fever - Coxiella burnetii - in domestic animals in State of Rio de Janeiro, Brazil.

    abstract:INTRODUCTION:Over the last recent years, the number of Q fever cases have has increased throughout the world. An epidemiological investigation was performed in the area in which the first molecular documentation of Q fever in Brazil was previously reported. METHODS:Indirect immunofluorescence assay (IFA) and PCR of Co...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Mares-Guia MA,Rozental T,Guterres A,Gomes R,Almeida DN,Moreira NS,Barreira JD,Favacho AR,Santana AL,Lemos ER

    更新日期:2014-03-01 00:00:00

  • Adult T-cell leukemia/lymphoma: report of two cases.

    abstract::Adult T-cell leukemia/lymphoma is a lymphoproliferative disorder of mature T lymphocytes associated with infection with human T-cell lymphotrophic virus type I (HTLV-I). Adult T-cell leukemia/lymphoma is characterized by clinical and laboratory polymorphism that allows it to be classified into four distinct subgroups:...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Olivo RA,Martins FF,Soares S,Moraes-Souza H

    更新日期:2008-05-01 00:00:00

  • Occurrence and risk factors associated with infection by Toxoplasma gondii in goats in the State of Alagoas, Brazil.

    abstract:INTRODUCTION:Goats are considered very susceptible to infection by Toxoplasma gondii and when this occurs during pregnancy, it may cause fetal death with subsequent fetal resorption, abortion, mummification, stillborn or the birth of weak goats. The objective of this work was to determine the occurrence of and identify...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Anderlini GA,Mota RA,Faria EB,Cavalcanti EF,Valença RM,Pinheiro Júnior JW,de Albuquerque PP,de Souza Neto OL

    更新日期:2011-03-01 00:00:00

  • [Adverse reactions in Chagas disease patients treated with benznidazole, in the State of Ceará].

    abstract:INTRODUCTION:Chagas disease is caused by Trypanosoma cruzi and treated with benznidazole (BNZ). This drug has the troublesome features of presenting partial effectiveness and high toxicity ranging from hypersensitivity reactions to medullary aplasia. The objective here was to describe and evaluate the occurrence of adv...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: de Pontes VM,Souza Júnior AS,Cruz FM,Coelho HL,Dias AT,Coêlho IC,Oliveira Mde F

    更新日期:2010-03-01 00:00:00

  • [Biochemistry of schistosomiasis mansoni: involvement of siderosomes in hepatic inflammatory processes].

    abstract::The inflammatory processes that develop during the advanced stages of hepatic schistosomiasis mansoni have been related in this study to: (a) accumulation of siderosomes; (b) capacity of the ferrous/ferric ions to unleash the formation of free radicals; (c) peroxidation of membrane lipids and; (d) reduction of stabili...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Rodrigues LE,Galle P

    更新日期:1990-04-01 00:00:00

  • Comparison of methodologies for detecting Trypanosoma cruzi parasites by microscopic observation of microhematocrit capillary tubes.

    abstract:INTRODUCTION:The microscopic examination of microhematocrit tubes (mHCT) has been proposed as the gold standard for acute and congenital Chagas disease diagnosis. We compared different mHCT methodologies detecting T. cruzi parasites in the blood. METHODS:The rotating method, water mount, and immersion oil methods were...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Vera-Ku M,Meza-González G,Carlier Y,Truyens C,Gamboa-León R

    更新日期:2019-06-27 00:00:00

  • HIV, hepatitis B and C, and syphilis prevalence and coinfection among sex workers in Southern Brazil.

    abstract:INTRODUCTION:Sex workers (SWs) are vulnerable to HIV, hepatitis, and syphilis coinfection. METHODS:A cross-sectional study was conducted in Tubarão, Laguna, and Imbituba, Southern Brazil. We surveyed 147 SWs using face-to-face interviews and blood sampling for serological evaluation. RESULTS:Prevalence of hepatitis B...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Schuelter-Trevisol F,Custódio G,Silva AC,Oliveira MB,Wolfart A,Trevisol DJ

    更新日期:2013-07-01 00:00:00

  • [Mortality caused by schistosomiasis in Brazil, 1977-1986].

    abstract::The authors present schistosomiasis mortality data in the country, in macrozones and in the federal units during the period of 1977-86. They relate mortality average to the control program. Its impact seems to be evident, especially concerning the population that underwent treatment. Here the reinfection risk has been...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Silveira AC,Vasconcelos MF,Melo JE

    更新日期:1990-07-01 00:00:00

  • Factors associated with a diagnosis of major depression among HIV-infected elderly patients.

    abstract:INTRODUCTION:Acquired immunodeficiency syndrome (AIDS) is being increasingly reported among the elderly and major depression (MD) may be associated with suboptimal adherence to treatment. METHODS:Cross-sectional study on factors associated with MD among 72 HIV-infected elderly individuals. RESULTS:Twenty (27.7%) pati...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Carmo Filho Ad,Fakoury MK,Eyer-Silva Wde A,Neves-Motta R,Kalil RS,Ferry FR

    更新日期:2013-05-01 00:00:00

  • Adverse systemic reaction to benznidazole.

    abstract::Benznidazole, drug of choice for Chagas disease (CD), has been associated with a high incidence of adverse reactions that can become serious, necessitating discontinuation of the drug. We describe the case of a Bolivian patient living in Spain for 9 years, who, following treatment with benznidazole for CD in indetermi...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical



    authors: Coronel MV,Frutos LO,Muñoz EC,Valle DK,Rojas DH

    更新日期:2017-01-01 00:00:00

  • Family COVID-19 cluster analysis of an infant without respiratory symptoms.

    abstract::Diagnosing cases of coronavirus disease (COVID-19) with only non-respiratory symptoms has been challenging. We reported the diagnosis of a child who tested positive for COVID-19 with abdominal pain/diarrhea and tracked his family cluster. One member of the family tested positive for COVID-19 on real-time reverse-trans...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Jesus MCS,Lima AGA,Santos VS,Storti-Melo LM,Moura TR,Santos RWFD,Santos CAD,Martins-Filho PR,Cuevas LE,Gurgel RQ

    更新日期:2020-01-01 00:00:00

  • Occurrence and distribution of triatomines (Hemiptera: Reduviidae) in municipalities of the Northeastern region of Minas Gerais State, Brazil.

    abstract:INTRODUCTION:Triatomines are targeted for the control of Chagas disease in endemic areas of Brazil. METHODS:Data regarding triatomines captured during 2001-2008 in 34 municipalities in the Northeast of Minas Gerais were analyzed. RESULTS:In total, 11,187 triatomines from eight species were captured, mostly in henhous...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Dias JV,Fernandes EG,Pires HH,Dias JC

    更新日期:2016-07-01 00:00:00

  • Comparison between clinical and ultrasonographic findings in cases of periportal fibrosis in an endemic area for schistosomiasis mansoni in Brazil.

    abstract:INTRODUCTION:Abdominal palpation and ultrasound findings among patients from an endemic area for schistosomiasis in Brazil who had been followed up for 27 years were compared. METHODS:In 2004, 411 patients from Brejo do Espírito Santo, in the State of Bahia, were selected for the present investigation after giving the...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Prata A,Ruiz-Guevara R,Antunes CM,Marinho CC,Queiroz LC,Voieta I,Lambertucci JR

    更新日期:2010-03-01 00:00:00

  • [A canine survey in a recent focus of cutaneous leishmaniasis in the city of Sabará, the metropolitan area of Belo Horizonte].

    abstract::In 1992, a dog naturally infected with Leishmania was found in a periurban area of Sabará, state of Minas Gerais, where human cutaneous leishmaniasis had been previously described. The parasite was classified as Leishmania, subgenus Viannia, which L. braziliensis, the main species of parasite present in the southeast ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Passos VM,Andrade AC,Silva ES,Figueiredo EM,Falcão AL

    更新日期:1996-07-01 00:00:00

  • Fulminant hepatic failure in children and adolescents in Northern Brazil.

    abstract::The histological findings of fulminant hepatic failure were correlated to the demographic, clinical, biochemical and virological features in children and adolescents, native to the Amazonas State in Northern Brazil. 96.2% had evidence of infection by primary hepatotrophic viruses. Histological analysis revealed three ...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Fonseca JC,Souza RA,Brasil LM,Araújo JR,Ferreira LC

    更新日期:2004-01-01 00:00:00

  • Diversity and dynamics of airborne fungi in São Luis, State of Maranhão, Brazil.

    abstract:INTRODUCTION:This study aimed to identify airborne fungi in São Luis, Maranhão, Brazil, to determine the prevalent genera and to correlate these genera with the area and season. METHODS:In total, 1,510 colony-forming units (CFUs) of airborne fungi were isolated from the north, south, east and west sides and from the c...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Bezerra GF,Gomes SM,Neto Silva MA,Santos RM,Filho Muniz WE,Viana GM,Nascimento Mdo D

    更新日期:2014-01-01 00:00:00

  • [Leishmania (Leishmania) chagasi infection in children from an endemic area of visceral leishmaniasis in the São Luís Island-MA, Brazil].

    abstract::A prospective study was undertaken in 648 children with less than 6 years of age in the municipality of Raposa, Maranhão, Brazil, from June 1997 to June 1998, to evaluate the characteristics of the infection by L.(L.)chagasi and verify if there is an association between malnutrition and asymptomatic infection. A stand...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Caldas AJ,Silva DR,Pereira CC,Nunes PM,Silva BP,Silva AA,Barral A,Costa JM

    更新日期:2001-09-01 00:00:00

  • Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens.

    abstract::The polypeptides of 46 and 58 kDa were recognized in different T. cruzi strains (Y, WSL and Colombiana) by serum of all chagasic patients studied. These polypeptides were isolated from T. cruzi Y strain and used in ELISA. The sensitivity and specificity were 97.6% [CI 95%: 86-100%] and 100% [CI 95%: 89.3-100%], respec...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Pereira VR,Nakazawa M,Furtado VC,Abath FG,Gomes YM

    更新日期:2000-07-01 00:00:00

  • Subdoses of primaquine in overweight patients and malaria vivax relapses: report of two cases in the Federal District, Brazil.

    abstract::Two cases of malaria by Plasmodium vivax relapsed after treatment with drugs in doses recommended by the Ministry of Health are presented. Both patients were overweight and were followed in the Federal District, an area considered free from vector transmission of the disease. Radical cure was obtained after medication...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Santos JB,Luz Fd,Deckers FA,Tauil PL

    更新日期:2010-11-01 00:00:00

  • [Infeccious diseases as causes of death in autopsied elderly].

    abstract::The population aging in Brazil was associated with the alterations in the morbimortality of the population. The aim of this study was to verify the causes of death and other pathological processes in autopsied elderly. The elderly with 60 years or more in the period from 1976 to 1998 represented 394 cases (24.4%). The...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: de Oliveira FA,dos Reis MA,Castro EC,da Cunha SF,Teixeira Vd Vde P

    更新日期:2004-01-01 00:00:00

  • [A dengue epidemic in Ipupiara and Prado, Bahia. A seroepidemiologic survey].

    abstract::Serologic studies in Brazil have indicated a 25% to 56% prevalence of dengue virus infections. However, these studies were carried out in populations of middle-sized and larger cities. The present study describes two epidemics of classic dengue fever in two small cities in the State of Bahia. The first occurred in 198...

    journal_title:Revista da Sociedade Brasileira de Medicina Tropical

    pub_type: 杂志文章


    authors: Vasconcelos PF,Mota K,Straatmann A,Santos-Torres S,da Rosa AP,Tavares Neto J

    更新日期:2000-01-01 00:00:00