First report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil.

Abstract:

INTRODUCTION:Carbapenemase-resistant enterobacteria that produce the bla NDM gene are found worldwide. However, this is the first report of blaNDM in Klebsiella aerogenes in Brazil. METHODS:The identification of bacterial species was performed using anautomated system and confirmed by biochemical tests, 16S rRNA gene sequencing, and detection of resistance genes. RESULTS:The clinical isolate showed minimum inhibitory concentration resistance to meropenem and polymyxin B at 8mg/L and 4mg/L, respectively. Only the blaNDM gene was detected. CONCLUSIONS:The current report of the blaNDM gene in isolated MDR enterobacteria indicates that this gene can spread silently in a hospital setting.

journal_name

Rev Soc Bras Med Trop

authors

Soares CRP,Oliveira-Júnior JB,Firmo EF

doi

10.1590/0037-8682-0262-2020

subject

Has Abstract

pub_date

2020-12-21 00:00:00

pages

e02622020

eissn

0037-8682

issn

1678-9849

pii

S0037-86822021000100610

journal_volume

54

pub_type

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