Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens.

Abstract:

:The polypeptides of 46 and 58 kDa were recognized in different T. cruzi strains (Y, WSL and Colombiana) by serum of all chagasic patients studied. These polypeptides were isolated from T. cruzi Y strain and used in ELISA. The sensitivity and specificity were 97.6% [CI 95%: 86-100%] and 100% [CI 95%: 89.3-100%], respectively when Tc 46 was used. When Tc 58 was used the sensitivity and specificity were 100% [CI 95%: 89.6-100%] and 90.2% [CI 95%: 75.9-96.8%], respectively.

journal_name

Rev Soc Bras Med Trop

authors

Pereira VR,Nakazawa M,Furtado VC,Abath FG,Gomes YM

doi

10.1590/s0037-86822000000400006

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

367-70

issue

4

eissn

0037-8682

issn

1678-9849

journal_volume

33

pub_type

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