Abstract:
INTRODUCTION:Chagas disease is caused by Trypanosoma cruzi. Wild and perianthropic mammals maintain the infection/transmission cycle, both in their natural habitat and in the peridomestic area. The aim of this paper was to present the results from a study on wild rodents in the central and northern regions of San Luis province, Argentina, in order to evaluate the prevalence of this infection. METHODS:Sherman traps were set up in capture areas located between latitudes 32 masculine and 33 masculine S, and longitudes 65 masculine and 66 masculine W. The captured rodents were taxonomically identified and hemoflagellates were isolated. Morphological, biometric and molecular studies and in vitro cultures were performed. Infection of laboratory animals and histological examination of the cardiac muscle and inoculation area were also carried out. Parasites were detected in circulating blood in Calomys musculinus, Graomys griseoflavus, Phyllotis darwini and Akodon molinae. The parasites were identified using biological criteria. Molecular PCR studies were performed on some isolates, which confirmed the characterization of these hemoflagellates as Trypanosoma cruzi. RESULTS AND CONCLUSIONS:Forty-four percent of the 25 isolates were identified as Trypanosoma cruzi, and the remaining 56% as Trypanosoma cruzi-like. These findings provide evidence that wild rats infected with Trypanosoma cruzi and Trypanosoma cruzi-like organisms are important in areas of low endemicity.
journal_name
Rev Soc Bras Med Tropjournal_title
Revista da Sociedade Brasileira de Medicina Tropicalauthors
Brigada AM,Doña R,Caviedes-Vidal E,Moretti E,Basso Bdoi
10.1590/s0037-86822010000300007subject
Has Abstractpub_date
2010-05-01 00:00:00pages
249-53issue
3eissn
0037-8682issn
1678-9849pii
S0037-86822010000300007journal_volume
43pub_type
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
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abstract::Congenital transmission of Trypanosoma cruzi infection in Argentina has being increasing its relative importance with control of vectorial and transfusional transmission growth. It is for this reason that vertical transmission is seen, in the future, as a continuous source of infected newborns, even with vectorial and...
journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
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journal_title:Revista da Sociedade Brasileira de Medicina Tropical
pub_type: 杂志文章
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