Incidence of tuberculous meningitis in the State of Santa Catarina, Brazil.

Abstract:

INTRODUCTION:The aim of this study was to estimate the incidence of tuberculous meningitis in the State of Santa Catarina (SC), Brazil, during the period from 2001 to 2010. METHODS:Ecological, temporal, and descriptive methods were employed using data obtained from the Information System on Disease Notification (Sistema de Informação de Agravos de Notificação). RESULTS:One hundred sixteen reported cases of tuberculous meningitis occurred from 2001 to 2010, corresponding to 1.2% (0.2 cases/100,000 inhabitants) of all meningitis cases reported in SC. There was a predominance of new cases in males, corresponding to 56.9% of new cases (0.2 cases/100,000 inhabitants; males vs. females; p=0.374), in patients aged 20-39 years, corresponding to 52.6% of new cases (0.5 cases/100,000 inhabitants; 20-39 years versus others; p<0.001), and in urban areas, corresponding to 91.4% of new cases (0.2 cases/100,000 inhabitants; urban vs. rural; p=0.003). In 48.3% of cases, the outcome was death. CONCLUSIONS:The incidence rate of tuberculous meningitis in SC has increased within the last decade, with the most affected population comprising young adult white males with an average education. Thus, tuberculous meningitis remains a serious disease, emphasizing the need for disease prevention with vaccination campaigns against tuberculosis, the development of faster and more accurate diagnostic methods, and the use of current epidemiological knowledge regarding the disease to facilitate the establishment of early treatment.

journal_name

Rev Soc Bras Med Trop

authors

Souza CH,Yamane A,Pandini JC,Ceretta LB,Ferraz F,da Luz GD,Simões PW

doi

10.1590/0037-8682-0122-2014

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

483-9

issue

4

eissn

0037-8682

issn

1678-9849

pii

S0037-86822014000400483

journal_volume

47

pub_type

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