Prognosis and clinical features of intractable epilepsy: a prospective study.

Abstract:

:Of the epileptic patients who were treated for > or = 5 years until the end of 1990 and had more than four seizures in 1990, 63 patients had been treated without interruption until the end of 1995. We analyzed their clinical courses from 1990 to 1995 prospectively. More than half the subjects were diagnosed with temporal lobe epilepsy. Twenty cases had presumed etiology, and 32 had neuropsychiatric complications. Of the subjects whose seizures were not controlled with conventional antiepileptic drugs (AED), 11 cases demonstrated significant improvement when new AED; that is, lamotrigine, vigabatrin, clobazam, topiramate, tiagabine or CGP33101 were added. However, 10 patients did not respond to new AED. Presumed etiology, neuropsychiatric complications, multiple epileptic foci in EEG and abnormalities on head CT or MRI were characteristics of the patients whose seizures were resistant to new AED.

authors

Wada K,Kiryu K,Kawata Y,Chiba T,Mizuno K,Okada M,Tasaki H,Fukushima Y,Saito F,Kaneko S

doi

10.1111/j.1440-1819.1997.tb02589.x

subject

Has Abstract

pub_date

1997-08-01 00:00:00

pages

233-5

issue

4

eissn

1323-1316

issn

1440-1819

journal_volume

51

pub_type

杂志文章
  • Surveys on the pregraduate and postgraduate education on child and adolescent psychiatry in Japan.

    abstract::The aim of the study is to clarify the results of Survey-1993 conducted by the committee on the education system in Japanese Society of Child and Adolescent Psychiatry regarding the present situation of education on child and adolescent psychiatry in Japan, and to compare these with the results of Survey-1982 conducte...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.1998.tb03245.x

    authors: Hayashi M,Yamazaki K

    更新日期:1998-12-01 00:00:00

  • A case of insufficient sleep syndrome.

    abstract::All night polysomnographic evaluation (PSG) soon after admission and at the late period of admission revealed an atypically high sleep efficiency and a prolonged total sleep time. Sleep onset latency and distribution of REM and NREM sleep stages were like those of normal sleepers. On REM latency, while it was remarkab...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.1998.tb01029.x

    authors: Yoshikawa N,Suzuki S,Ishimoto T,Matsumoto M,Miyagishi T

    更新日期:1998-04-01 00:00:00

  • Abnormalities of P300 cortical current density in unmedicated depressed patients revealed by LORETA analysis of event-related potentials.

    abstract::The purpose of the present study was to investigate the neural substrates underlying event-related potential (ERP) abnormalities, with respect to the generators of the ERP components in depressed patients. Using an oddball paradigm, ERP from auditory stimuli were recorded from 22 unmedicated patients with current depr...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2004.01195.x

    authors: Kawasaki T,Tanaka S,Wang J,Hokama H,Hiramatsu K

    更新日期:2004-02-01 00:00:00

  • Involvement of nucleus accumbens dopaminergic transmission in acoustic startle: observations concerning prepulse inhibition in rats with entorhinal cortex lesions.

    abstract::The relationship between the entorhinal cortex and prepulse inhibition (PPI) as well as the nucleus accumbens dopaminergic participation in acoustic startle were examined in rats. After the entorhinal cortex was damaged bilaterally using ibotenic acid, a microdialysis probe was placed in the nucleus accumbens for dete...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2004.01281.x

    authors: Goto K,Ueki A,Iso H,Morita Y

    更新日期:2004-08-01 00:00:00

  • Course and outcome of bipolar II disorder: a retrospective study.

    abstract::To study course and outcome of Bipolar II disorder, 217 major depressive episode (MDE) patients were interviewed with Structured Clinical Interview for DSM-IV. Patients with more than three MDE and patients with fewer MDE were compared. Patients with more than three MDE were 77.8%. Comparisons, controlled for confound...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1046/j.1440-1819.2001.00786.x

    authors: Benazzi F

    更新日期:2001-02-01 00:00:00

  • Patterns of self-cutting: a preliminary study on differences in clinical implications between wrist- and arm-cutting using a Japanese juvenile detention center sample.

    abstract::The present study was aimed to clarify the differences in clinical implications between wrist- and arm-cutting. Subjects were 201 delinquent adolescents (178 males and 23 females) who had been admitted to a detention center from February to March 2003. A self-reporting questionnaire and the Adolescent Dissociative Exp...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2004.01271.x

    authors: Matsumoto T,Yamaguchi A,Chiba Y,Asami T,Iseki E,Hirayasu Y

    更新日期:2004-08-01 00:00:00

  • Substance abuse, conduct disorder and crime: assessment in a juvenile detention house in Istanbul, Turkey.

    abstract::The purpose of the present study was to determine the rate of substance abuse in the juvenile detention house and to determine the relationship between crime and substance abuse and conduct disorder. Two hundred and thirty cases in the biggest juvenile detention house in Istanbul, Turkey were assessed according to Dia...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1440-1819.2005.01350.x

    authors: Copur M,Turkcan A,Erdogmus M

    更新日期:2005-04-01 00:00:00

  • Serotonin syndrome during clomipramine monotherapy: comparison of two diagnostic criteria.

    abstract::Incidence of serotonin syndrome was determined by two different diagnostic criteria during clomipramine monotherapy. Incidence, determined by Sternbach's criteria, was 12.1% (8/66 patients), and that determined by the criteria of Dursun et al. was 3.0% (2/66 patients). The two patients who met the latter criteria also...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1440-1819.1997.tb02365.x

    authors: Kudo K,Sasaki I,Tsuchiyama K,Akiyoshi J,Nagayama H,Fujii I

    更新日期:1997-02-01 00:00:00

  • Effects of bright light at lunchtime on sleep in patients in a geriatric hospital II.

    abstract::Inpatients with sleep disturbances in a geriatric hospital received 1 h of exposure to approximately 8000 lx bright light per day for 3 weeks. Polysomnogram was recorded for four female patients. Two (aged 68 and 87 years) were non-demented patients with weak cataracts and the other two (aged 92 and 93 years) were dem...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1046/j.1440-1819.2001.00864.x

    authors: Fukuda N,Kobayashi R,Kohsaka M,Honma H,Sasamoto Y,Sakakibara S,Koyama E,Nakamura F,Koyama T

    更新日期:2001-06-01 00:00:00

  • Prevalence of depressive symptoms in Japanese male patients with chronic obstructive pulmonary disease.

    abstract:AIM:The objective of this study was to utilize commonly applied tools, the Hospital Anxiety and Depression Scale - Depression subscale (HADS-D) and the Center for Epidemiological Studies Depression Scale (CES-D), to screen for depressive symptoms in patients with stable chronic obstructive pulmonary disease (COPD). Fur...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2010.02171.x

    authors: Hayashi Y,Senjyu H,Iguchi A,Iwai S,Kanada R,Honda S,Ozawa H

    更新日期:2011-02-01 00:00:00

  • Socioeconomic and familial factors in the involuntary hospitalization of patients with schizophrenia.

    abstract::In the catchment area of Matsumoto Public Health Center in Japan, 44 schizophrenic patients admitted between April 1992 and March 1997 under the national policy Involuntary Hospitalization Ordered by Prefectural Governor (IHOPG) were compared with 61 schizophrenic patients admitted under another policy, Hospitalizatio...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2004.01185.x

    authors: Hattori I,Higashi T

    更新日期:2004-02-01 00:00:00

  • Application of the relaxation technique in general hospital psychiatry.

    abstract::The present article demonstrates the clinical application and the efficacy of relaxation techniques in general hospital psychiatry in Japan. During April to December 1993, 20 patients were treated with progressive muscle relaxation and "modified' autogenic training therapies. The targeted symptoms were anxiety attacks...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.1995.tb01898.x

    authors: Hosaka T,Yamamoto K,Ikeda K,Taniyama F,Yanagisawa J

    更新日期:1995-12-01 00:00:00

  • Serum carnitine and disabling fatigue in multiple sclerosis.

    abstract::The serum concentrations of total, free and acylcarnitine were compared in 25 patients with multiple sclerosis (MS) and among age- and sex-matched normal controls by the new enzymatic cycling method in order to clarify whether the fatigue in MS might be due to possible carnitine-related fatty acid metabolic abnormalit...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.1996.tb00573.x

    authors: Fukazawa T,Sasaki H,Kikuchi S,Hamada T,Tashiro K

    更新日期:1996-12-01 00:00:00

  • The hypnotic effects of melatonin treatment on diurnal sleep in humans.

    abstract::This study investigated the hypnotic effects of 10 mg melatonin and placebo, which were administered at 10.00 h, according to a single-blind crossover design, on an 8-h diurnal sleep from 11.00 to 19.00 h, following a full night of sleep. The subjects were six healthy male students, each of whom underwent polysomnogra...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1440-1819.1999.00480.x

    authors: Matsumoto M

    更新日期:1999-04-01 00:00:00

  • Lack of association between the interleukin-1 gene complex and schizophrenia in a Japanese population.

    abstract::Interleukin-1 (IL1) is an inflammatory cytokine and exerts neurodegenerative effects in the brain. Several studies have indicated that IL1 is likely to be involved in the pathogenesis of schizophrenia. Recent genetic studies have revealed that the IL1 gene complex (IL,1 alpha, IL1, beta and IL1 receptor antagonist) wa...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2007.01671.x

    authors: Watanabe Y,Nunokawa A,Kaneko N,Muratake T,Koizumi M,Someya T

    更新日期:2007-08-01 00:00:00

  • Effects of circadian typology on sleep-wake behavior of air traffic controllers.

    abstract::The effects of circadian typology on sleep-wake behavior in shiftworkers were investigated using wrist actigraph in 18 air traffic controllers (ATC), nine morning types and nine evening types, working in a backward 1-1-1 super rapid rotation shift schedule. The ATC wore a wrist actigraph continuously over 6 days (3 da...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1046/j.1440-1819.2003.01160.x

    authors: Natale V,Martoni M,Cicogna P

    更新日期:2003-10-01 00:00:00

  • Acute confusional state after designer tryptamine abuse.

    abstract::A 23-year-old Japanese woman was brought to the emergency department about 6.5 h after taking liquid and later a half tablet purchased on the street. About 4.5 h prior to presentation, she displayed excited and disorganized behavior. On examination, she was not alert or oriented, with a Glasgow Coma Scale score of 13,...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2007.01638.x

    authors: Itokawa M,Iwata K,Takahashi M,Sugihara G,Sasaki T,Abe Y,Uno M,Hobo M,Jitoku D,Inoue K,Arai M,Yasuda I,Shintani M

    更新日期:2007-04-01 00:00:00

  • Patient and family factors associated with family accommodation in obsessive-compulsive disorder.

    abstract:AIM:Obsessive-compulsive disorder (OCD) impacts family functioning as family members modify their personal and family routines, participate in rituals, and provide reassurance. These behaviors have been identified as family accommodation (FA), a phenomenon that, if ignored, may facilitate OCD symptoms and lead to poore...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/pcn.12172

    authors: Gomes JB,Van Noppen B,Pato M,Braga DT,Meyer E,Bortoncello CF,Cordioli AV

    更新日期:2014-08-01 00:00:00

  • Effects of bright light on cognitive and sleep-wake (circadian) rhythm disturbances in Alzheimer-type dementia.

    abstract::Twenty-seven patients with Alzheimer-type dementia (ATD) were treated with bright light therapy in the morning for four consecutive weeks. The cognitive state of each patient was evaluated with the Mini-Mental-State Examination (MMSE) and circadian rhythm with actigram before and after therapy for all of the patients ...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1046/j.1440-1819.2000.00711.x

    authors: Yamadera H,Ito T,Suzuki H,Asayama K,Ito R,Endo S

    更新日期:2000-06-01 00:00:00

  • Reception of Kraepelin's ideas 1900-1960.

    abstract::Kraepelin's system of mental diseases has contributed substantially to the foundation of modern psychiatric diagnosis in the DSM-IV and ICD-10. Considering Kraepelin's influence in the creation of these diagnostic tools, the question arises as to how Kraepelin's contemporaries and successors reacted to his nosology. H...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 传,历史文章,杂志文章

    doi:10.1111/j.1440-1819.2011.02226.x

    authors: Palm U,Möller HJ

    更新日期:2011-06-01 00:00:00

  • Neural mechanisms underlying adaptive and maladaptive consequences of stress: Roles of dopaminergic and inflammatory responses.

    abstract::Stress caused by adverse and demanding conditions, a risk factor for mental illnesses, induces adaptive or maladaptive neural and behavioral consequences, depending on the conditions. Studies using rodent stress models have revealed multiple mechanisms related to dopamine and inflammation for stress-induced neural and...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章,评审

    doi:10.1111/pcn.12901

    authors: Furuyashiki T,Kitaoka S

    更新日期:2019-11-01 00:00:00

  • Clinical significance of sleep-related breathing disorder in narcolepsy.

    abstract::Both the influence of comorbid obstructive sleep apnea-hypopnea syndrome (OSAHS) on daytime sleepiness and its pathological mechanism in 10 narcoleptic patients was studied. Mild elevation of esophageal negative pressure and obstruction in the velopharyngeal area, as observed by upper airway magnetic resonance imaging...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1046/j.1440-1819.2002.00962.x

    authors: Inoue Y,Nanba K,Higami S,Honda Y,Takahashi Y,Arai H

    更新日期:2002-06-01 00:00:00

  • Fronto-limbic abnormalities in a patient with compulsive hoarding: a 99mTc-ECD SPECT study.

    abstract::Little is known about the neuronal mechanism underpinning the pathophysiology of compulsive hoarding. We report the cerebral blood flow changes in an obsessive-convulsive patient with severe hoarding. The patient showed hyperperfusion of the fronto-temporal region and hypoperfusion of the striatal, the middle cingulat...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2010.02120.x

    authors: Ohtsuchi H,Matsuo K,Akimoto T,Watanabe Y

    更新日期:2010-10-01 00:00:00

  • Distress and functioning in mixed anxiety and depressive disorder.

    abstract::The aim of the present study was to evaluate the validity of mixed anxiety and depressive disorder (MADD) with reference to functional characteristics and symptomatic characteristics in comparison with anxiety disorders, depressive disorders, and groups showing subthreshold symptoms (exclusively depressive or anxiety ...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2006.01482.x

    authors: Małyszczak K,Pawłowski T

    更新日期:2006-04-01 00:00:00

  • Event-related potential correlates of functional hearing loss: reduced P3 amplitude with preserved N1 and N2 components in a unilateral case.

    abstract::A female patient exhibiting functional hearing loss in her left ear demonstrated reduced amplitude of P3 component in event-related potentials (ERP) to left monaural stimulation, with preserved N1 and N2 components to stimulation of either ear. This result suggested that stimuli in the affected ear were conducted succ...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.1996.tb01668.x

    authors: Fukuda M,Hata A,Niwa S,Hiramatsu K,Yokokoji M,Hayashida S,Itoh K,Nakagome K,Iwanami A

    更新日期:1996-04-01 00:00:00

  • Neural correlates of memory in depression measured by brain perfusion SPECT at rest.

    abstract:AIM:Brain metabolism activated studies have indicated associations between memory and the anterior cingulate cortex and hippocampus in patients with depression. The aim of the present study was therefore to investigate memory function, measured as performance on the Wechsler Memory Scale-Revised (WMS-R), and its relati...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2009.02013.x

    authors: Azuma H,Segawa K,Nakaaki S,Murata Y,Kawakami K,Tohyama J,Iidaka T,Shinagawa Y,Nakano Y,Yamada A,Watanabe N,Hongo J,Akechi T,Furukawa TA

    更新日期:2009-10-01 00:00:00

  • A novel method of time series analysis, and an application to the study of human sleep electroencephalogram.

    abstract::A new mathematical method was developed to analyze time series. Applications of this method to the delta component of all-night sleep electroencephalogram (EEG) revealed new variations with double-rapid eye movement (REM)-sleep interval. The proposed method entails repeated application of the least squares spectrum. F...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1046/j.1440-1819.1998.00450.x

    authors: Koga E,Tsuji Y

    更新日期:1998-10-01 00:00:00

  • Serum ghrelin is inversely associated with cognitive function in a sample of non-demented elderly.

    abstract:AIM:The orexigenic hormone, ghrelin, is linked to learning and memory in animal studies. No previous study has investigated whether cognition is related to ghrelin in the non-demented elderly. METHODS:Thirty-five older adults underwent neuropsychological testing and fasting blood draw with subsequent serum ghrelin qua...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.2010.02145.x

    authors: Spitznagel MB,Benitez A,Updegraff J,Potter V,Alexander T,Glickman E,Gunstad J

    更新日期:2010-12-01 00:00:00

  • The activities of the Tokyo Center.

    abstract::The main World Health Organization (WHO) activities of the Tokyo Center are as follows: (1) It performed the research project entitled 'A Bio-Psycho-Social Study on Children with Emotional and Behavioral Problems' in cooperation with the Beijing and Seoul Centers from 1985 to 1987. These results suggested that the dev...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.1998.tb03265.x

    authors: Matsushima E,Kojima T,Obayashi S,Ohta K,Ando K,Toru M,Shimazono Y,Takebayashi H,Takahashi S,Xia ML,Ohkura T,Yoshino M,Okubo Y,Matsuura M,Ando H

    更新日期:1998-12-01 00:00:00

  • Psychiatric manifestations accompanying interferon therapy for patients with chronic hepatitis C: an overview of cases in Japan.

    abstract::Thirty case reports published in Japan that refer to psychiatric symptoms accompanying interferon (IFN) therapy were examined. These papers covered a total of 49 cases. We categorized these 49 cases into 35 cases of mood disorder, 10 of delirium and four of psychotic disorder. The key findings of our study of these ca...

    journal_title:Psychiatry and clinical neurosciences

    pub_type: 杂志文章

    doi:10.1111/j.1440-1819.1997.tb02579.x

    authors: Nozaki O,Takagi C,Takaoka K,Takata T,Yoshida M

    更新日期:1997-08-01 00:00:00