Fronto-limbic abnormalities in a patient with compulsive hoarding: a 99mTc-ECD SPECT study.

Abstract:

:Little is known about the neuronal mechanism underpinning the pathophysiology of compulsive hoarding. We report the cerebral blood flow changes in an obsessive-convulsive patient with severe hoarding. The patient showed hyperperfusion of the fronto-temporal region and hypoperfusion of the striatal, the middle cingulate and the medial temporal regions during the stage with severe symptoms. Following improvement from the hoarding behaviors, the extent of hypoperfusion was expanded in the bilateral striatum, the anterior and middle cingulate gyrus. The result may substantiate evidence of the fronto-limbic abnormality involved in the pathophysiology of compulsive hoarding.

authors

Ohtsuchi H,Matsuo K,Akimoto T,Watanabe Y

doi

10.1111/j.1440-1819.2010.02120.x

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

580-3

issue

5

eissn

1323-1316

issn

1440-1819

pii

PCN2120

journal_volume

64

pub_type

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