Abstract:
AIM:The orexigenic hormone, ghrelin, is linked to learning and memory in animal studies. No previous study has investigated whether cognition is related to ghrelin in the non-demented elderly. METHODS:Thirty-five older adults underwent neuropsychological testing and fasting blood draw with subsequent serum ghrelin quantification. RESULTS:Ghrelin was negatively correlated with several cognitive domains, including verbal memory, working memory, and naming. CONCLUSION:Areas of cognition associated with ghrelin level were similar to the pattern of deficits observed in early Alzheimer's disease. Findings suggest a potential moderational role of ghrelin in pathological cognitive decline. Further work investigating mechanisms is needed.
journal_name
Psychiatry Clin Neuroscijournal_title
Psychiatry and clinical neurosciencesauthors
Spitznagel MB,Benitez A,Updegraff J,Potter V,Alexander T,Glickman E,Gunstad Jdoi
10.1111/j.1440-1819.2010.02145.xsubject
Has Abstractpub_date
2010-12-01 00:00:00pages
608-11issue
6eissn
1323-1316issn
1440-1819journal_volume
64pub_type
杂志文章abstract::The present paper describes cognitive approaches to the treatment of a major depressive episode in a patient with residual schizophrenia. The goal of therapy was to increase and stabilize the patient's physical activity through decreasing dysfunctional cognition pertinent to inertia. A therapeutic strategy of 'schedul...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.1999.00606.x
更新日期:1999-10-01 00:00:00
abstract:AIM:Neuroimaging-based multivariate pattern-recognition methods have been successfully used to develop diagnostic algorithms to distinguish patients with major depressive disorder (MDD) from healthy controls (HC). We developed and evaluated the accuracy of a multivariate classification method for the differentiation of...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/pcn.12862
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abstract:AIMS:The reasons for accessing and maintaining access to mental health services in Japan may be different to those in other countries. Using the World Health Organization World Mental Health Japan survey data, this study investigated the prevalence of sociodemographic correlates of barriers for the use of, reasons for ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/pcn.12267
更新日期:2015-09-01 00:00:00
abstract::Open-system social skills training (SST) was performed in an open psychiatric ward of the hospital of Yokohama City University. Between June 1998 and March 2000, 223 patients were being treated for various mental disorders and 136 of these patients voluntarily participated in the open-system SST at least once. The SST...
journal_title:Psychiatry and clinical neurosciences
pub_type: 临床试验,杂志文章
doi:10.1046/j.1440-1819.2003.01120.x
更新日期:2003-06-01 00:00:00
abstract::This study evaluated the effects of the daytime nap on performance, mood and physiological measures in aged individuals Participants were six healthy aged persons (M=72.2 years old) who habitually napped in the afternoon three or more times a week. They participated under two conditions with an interval of 1 week. In ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.1999.00548.x
更新日期:1999-04-01 00:00:00
abstract::Attentional processes play a central role in information selection, which is impaired in schizophrenic patients. In the present study, we attempted to characterize the attentional performance of chronic schizophrenics using a computerized assessment of the multiple components of attentional function. Two comparable sa...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.2002.01031.x
更新日期:2002-08-01 00:00:00
abstract:AIMS:This paper examines the relationship between observational behavior and the observers' result assumptions, using a contained diagram that includes significant non-verbal information, such as gestures. The ability of care workers to assess a patient's mental status on the basis of non-verbal information would be co...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2010.02077.x
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.2003.01094.x
更新日期:2003-04-01 00:00:00
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journal_title:Psychiatry and clinical neurosciences
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.1998.tb01049.x
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.1998.tb00969.x
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.1999.00513.x
更新日期:1999-04-01 00:00:00
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journal_title:Psychiatry and clinical neurosciences
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doi:10.1111/j.1440-1819.2009.02011.x
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/pcn.12668
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journal_title:Psychiatry and clinical neurosciences
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doi:10.1111/j.1440-1819.2004.01238.x
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.1998.tb01059.x
更新日期:1998-04-01 00:00:00
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.1998.tb00979.x
更新日期:1998-02-01 00:00:00
abstract::This study indexed the mental status in six living donor liver transplantations (LDLT) performed at the Juntendo University Hospital between 2005 and 2007. The donors' preoperative and postoperative psychiatric and psychological status was assessed using the Profile of Mood States (POMS) and the State-Trait Anxiety In...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2009.01992.x
更新日期:2009-08-01 00:00:00
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journal_title:Psychiatry and clinical neurosciences
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2010.02071.x
更新日期:2010-04-01 00:00:00
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/pcn.12526
更新日期:2017-08-01 00:00:00
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journal_title:Psychiatry and clinical neurosciences
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journal_title:Psychiatry and clinical neurosciences
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journal_title:Psychiatry and clinical neurosciences
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2006.01492.x
更新日期:2006-04-01 00:00:00
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journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
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更新日期:2011-08-01 00:00:00
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journal_title:Psychiatry and clinical neurosciences
pub_type: 临床试验,杂志文章
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