Abstract:
:The aim of the present study was to evaluate the validity of mixed anxiety and depressive disorder (MADD) with reference to functional characteristics and symptomatic characteristics in comparison with anxiety disorders, depressive disorders, and groups showing subthreshold symptoms (exclusively depressive or anxiety related). The present study was carried out in the following three medical settings: two psychiatric and one primary care. Patients seeking care in psychiatric institutions due to anxiety and depressive symptoms and attending primary medical settings for any reason were taken into account. A total of 104 patients (65 women and 39 men, mean age 41.1 years) were given a General Health Questionnaire (GHQ-30), Global Assessment of Functioning (GAF) and Present State Examination questionnaire, a part of Schedules for Clinical Assessment in Neuropsychiatry, Version 2.0. There were no statistically relevant differences between MADD and anxiety disorders in median GHQ score (19 vs 16) and median GAF score (median 68.5 vs 65). When considering depressive disorders the median GHQ score (28) was higher, and median GAF score (59) was lower than that in MADD. In groups with separated subthreshold anxiety or depressive symptoms, median GHQ scores (12) were lower and median GAF scores (75) were higher than that in MADD. The most frequent symptoms of MADD are symptoms of generalized anxiety disorder (GAD) and depression. Mixed anxiety and depressive disorder differs significantly from GAD only in higher rates of depressed mood and lower rates of somatic anxiety symptoms. Distinction from depression was clearer; six of 10 depressive symptoms are more minor in severity in MADD than in the case of depression. Distress and interference with personal functions in MADD are similar to that of other anxiety disorders. A pattern of MADD symptoms locates this disorder between depression and GAD.
journal_name
Psychiatry Clin Neuroscijournal_title
Psychiatry and clinical neurosciencesauthors
Małyszczak K,Pawłowski Tdoi
10.1111/j.1440-1819.2006.01482.xsubject
Has Abstractpub_date
2006-04-01 00:00:00pages
168-73issue
2eissn
1323-1316issn
1440-1819pii
PCNjournal_volume
60pub_type
杂志文章abstract::The aim of the present study was to provide basic descriptive data regarding utilization of 12-month mental health services in the Japanese community population. Face-to-face household surveys were carried out in four areas (two urban cities and two rural municipalities), and a total of 1663 persons participated (over...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2006.01492.x
更新日期:2006-04-01 00:00:00
abstract::Little is known about the neuronal mechanism underpinning the pathophysiology of compulsive hoarding. We report the cerebral blood flow changes in an obsessive-convulsive patient with severe hoarding. The patient showed hyperperfusion of the fronto-temporal region and hypoperfusion of the striatal, the middle cingulat...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2010.02120.x
更新日期:2010-10-01 00:00:00
abstract::In order to offer health education to the general population, taking into account not only their physical health but also their QOL (quality of life), it is necessary to clarify what guidance should be provided in the sight of QOL. In this study, the relationship between QOL and lifestyle was investigated in 615 Japan...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2004.01315.x
更新日期:2004-12-01 00:00:00
abstract:AIM:Recent cognitive neuroscience research shows that noninvasive brain stimulation can modify a wide range of behaviors in healthy people. Such regulation effects on human behaviors provide new insights into the neurobiology of cognitive processes and establish causal brain-behavior relations. Here, we aimed to examin...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章,评审
doi:10.1111/pcn.13025
更新日期:2020-09-01 00:00:00
abstract::Thirty case reports published in Japan that refer to psychiatric symptoms accompanying interferon (IFN) therapy were examined. These papers covered a total of 49 cases. We categorized these 49 cases into 35 cases of mood disorder, 10 of delirium and four of psychotic disorder. The key findings of our study of these ca...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.1997.tb02579.x
更新日期:1997-08-01 00:00:00
abstract::In order to clarify the characteristics of Behavioral and Psychological Symptoms of Dementia (BPSD) in patients with mild Alzheimer's disease (AD), BPSD among the severities of Clinical Dementia Rating (CDR) in 74 patients with AD were compared using the Neuropsychiatric inventory (NPI). The result, when compared betw...
journal_title:Psychiatry and clinical neurosciences
pub_type: 临床试验,杂志文章
doi:10.1111/j.1440-1819.2005.01371.x
更新日期:2005-06-01 00:00:00
abstract::Kraepelin's system of mental diseases has contributed substantially to the foundation of modern psychiatric diagnosis in the DSM-IV and ICD-10. Considering Kraepelin's influence in the creation of these diagnostic tools, the question arises as to how Kraepelin's contemporaries and successors reacted to his nosology. H...
journal_title:Psychiatry and clinical neurosciences
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1440-1819.2011.02226.x
更新日期:2011-06-01 00:00:00
abstract::We describe the test-retest reliability of the Personality Diagnostic Questionnaire: Revised (PDQ-R), which was developed to assess DSM-III-R personality disorders (PD). Thirty patients, diagnosed clinically with PD, filled out the PDQ-R twice at 1 month intervals after having undergone 8 weeks of treatment leading to...
journal_title:Psychiatry and clinical neurosciences
pub_type: 临床试验,杂志文章
doi:10.1111/j.1440-1819.1997.tb02601.x
更新日期:1997-12-01 00:00:00
abstract:AIMS:The aim of the present study was to examine how copy organization mediated immediate recall among patients with schizophrenia using the Rey-Osterrieth Complex Figure Test (ROCF). METHODS:The Boston Qualitative Scoring System (BQSS) was applied for qualitative and quantitative analyses of ROCF performances. Subjec...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2008.01821.x
更新日期:2008-08-01 00:00:00
abstract::Although atypical antipsychotics have been associated with improvements in cognitive function in schizophrenia, the neurochemical basis for such effects is not well understood. Candidate neurotransmitter systems primarily involve dopamine and serotonin. The current study explored this issue by examining the cognitive ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2006.01534.x
更新日期:2006-08-01 00:00:00
abstract::Lack of insight into illness is a prevalent and distinguishing feature of schizophrenia, which has a complex history and has been given a variety of definitions. Currently, insight is measured and treated as a multidimensional phenomenon, because it is believed to result from psychological, neuropsychological and orga...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章,评审
doi:10.1111/j.1440-1819.2012.02325.x
更新日期:2012-04-01 00:00:00
abstract:AIMS:Long-term use of methamphetamine could induce psychosis, but consequences with regards to intelligence have seldom been investigated. Long-term use of alcohol could also result in intellectual deterioration. METHODS:The IQ of 34 methamphetamine-induced psychosis (MIP) patients (age, 28.7 +/- 6.1 years) and 34 alc...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2009.02035.x
更新日期:2010-02-01 00:00:00
abstract::Delusions associated with cerebrovascular diseases have been sporadically reported. Although both psychiatrists and neurologists attempted to link delusions with anatomical locations of the brain lesion, comorbid psychiatric and neurological disorders make the interpretation of delusions difficult. The purpose of the ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.2001.00798.x
更新日期:2001-04-01 00:00:00
abstract:AIMS:The purpose of the present study was to investigate the relationship between delusional thoughts (delusional ideation or misidentification) and frontal lobe function using the Japanese version of the Frontal Assessment Battery (FAB) bedside screening neuropsychological test in early stage Alzheimer's disease (AD) ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 临床试验,杂志文章
doi:10.1111/j.1440-1819.2009.01968.x
更新日期:2009-08-01 00:00:00
abstract:AIM:In the present study, we investigated the changes in P3 component in the emotionally charged visual event-related potentials (ERP) in 30 drug-naïve schizophrenic patients for up to 1 year. METHODS:Visual oddball event-related potential was recorded from six recording sites for crying baby or smiling baby photograp...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2012.02345.x
更新日期:2012-06-01 00:00:00
abstract::The uses of lorazepam and electroconvulsive therapy (ECT) have been proven to be effective in treating catatonia. In the present study a modified treatment strategy (i.e. lorazepam i.m. injection or diazepam infused i.v. if lorazepam failed, not with ECT) was proposed to rapidly relieve catatonic signs in patients wit...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2005.01331.x
更新日期:2005-02-01 00:00:00
abstract::Two cases of tardive dystonia are reported. The first case was an 18-year-old schizophrenic woman suffering from parkinsonism and hypotension induced by antipsychotic drugs. Risperidone (4 mg/day) was added to her drug regimen and after increasing the dosage to 6 mg/day, she began to exhibit retrocollis. The second ca...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.2000.00743.x
更新日期:2000-08-01 00:00:00
abstract::The relationship between the entorhinal cortex and prepulse inhibition (PPI) as well as the nucleus accumbens dopaminergic participation in acoustic startle were examined in rats. After the entorhinal cortex was damaged bilaterally using ibotenic acid, a microdialysis probe was placed in the nucleus accumbens for dete...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2004.01281.x
更新日期:2004-08-01 00:00:00
abstract::Schizotypal personality disorder (SPD) has rarely been reported as an eating disorder-related personality trait. A 23-year-old woman was diagnosed as having anorexia nervosa binge eating/purging type. At the age of 53 years, she was admitted to Jikei University Hospital because of excessive bodyweight loss. She was di...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2007.01670.x
更新日期:2007-08-01 00:00:00
abstract::Little is known about the pathophysiology of somatization. The authors' aim was to explore associated factors with somatoform disorders. The authors studied 10 female patients with a diagnosis of somatization disorder or undifferentiated somatoform disorder with no comorbid current Diagnostic and Statistical Manual of...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2006.01581.x
更新日期:2006-12-01 00:00:00
abstract::To elucidate the effects of the bombing on the atomic bomb survivors' mental health, a mental health survey was conducted using a 12-item version of the General Health Questionnaire (GHQ-12) and a mail survey on atomic bomb exposure conditions and lifestyle using a self-administered questionnaire. A total of 3526 atom...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.2002.01057.x
更新日期:2002-10-01 00:00:00
abstract:AIM:The objective of this study was to utilize commonly applied tools, the Hospital Anxiety and Depression Scale - Depression subscale (HADS-D) and the Center for Epidemiological Studies Depression Scale (CES-D), to screen for depressive symptoms in patients with stable chronic obstructive pulmonary disease (COPD). Fur...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2010.02171.x
更新日期:2011-02-01 00:00:00
abstract:AIM:We investigated preclinical abnormalities as revealed by transcranial sonography (TCS) in patients with idiopathic rapid eye movement sleep behavior disorder (iRBD) compared with those revealed in patients with multiple system atrophy (MSA) or Parkinson's disease (PD) and in normal controls. METHODS:Twenty-two pat...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/pcn.12483
更新日期:2017-04-01 00:00:00
abstract::This study evaluated the effects of the daytime nap on performance, mood and physiological measures in aged individuals Participants were six healthy aged persons (M=72.2 years old) who habitually napped in the afternoon three or more times a week. They participated under two conditions with an interval of 1 week. In ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.1999.00548.x
更新日期:1999-04-01 00:00:00
abstract::Hikikomori, a severe form of social withdrawal, has long been observed in Japan mainly among youth and adolescents since around the 1970s, and has been especially highlighted since the late 1990s. Moreover, hikikomori-like cases have recently been reported in many other countries. Hikikomori negatively influences not ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章,评审
doi:10.1111/pcn.12895
更新日期:2019-08-01 00:00:00
abstract:AIMS:Alterations in cortisol and dehydroepiandrosterone sulfate (DHEA-S) levels are thought to play a role in the pathophysiology of neuropsychiatric disorders, including schizophrenia. The aim of this study was to investigate the role of serum cortisol and DHEA-S in the pathophysiology of schizophrenia. METHODS:Sixty...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.2011.02252.x
更新日期:2011-10-01 00:00:00
abstract:AIM:Rare variations are suggested to play a role in the genetic etiology of schizophrenia; to further investigate their role, we performed a three-stage study in a Japanese population. METHODS:In the first stage, we performed whole-exome sequencing (WES) of two parent-affected offspring trios. In the second stage, we ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/pcn.12526
更新日期:2017-08-01 00:00:00
abstract::The aim of this study was to test different definitions of depressive mixed state (DMX) (major depressive episode (MDE) with some concurrent hypomanic symptoms), to find which one could better define DMX. Unipolar and bipolar II MDE outpatients (n = 168) were interviewed with the DSM-IV Structured Clinical Interview. ...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1046/j.1440-1819.2001.00919.x
更新日期:2001-12-01 00:00:00
abstract::Major depression is highly prevalent among HIV-positive patients (HIVpp). The prevalence of depression ranges between 18% and 81%, depending on the population studied and the methodology of the study. The etiology of depression in HIVpp is likely determined by: (i) biological factors (alterations in the white matter s...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章,评审
doi:10.1111/pcn.12097
更新日期:2014-02-01 00:00:00
abstract::In September 1987 in Japan, the Mental Hygiene Law was amended to the Mental Health Law. This Law emphasizes the protection of human rights of the mentally disabled as well as the promotion of their social rehabilitation. In 1993, Mental Health Law was partially revised in the following four areas: (i) social rehabili...
journal_title:Psychiatry and clinical neurosciences
pub_type: 杂志文章
doi:10.1111/j.1440-1819.1998.tb03235.x
更新日期:1998-12-01 00:00:00