Patient selection for an upper extremity neuroprosthesis in tetraplegic individuals.

Abstract:

:One hundred and twenty persons with new onset traumatic tetraplegia consecutively admitted to our rehabilitation service were screened for consideration for use of an upper extremity neuroprosthesis. Strict inclusion criteria allowed only for participation of patients with ASIA impairment scale A, B or C injuries at the C5 or C6 level. One hundred and six persons were excluded from participation for the following reasons: five patients died, 27 had central cord syndrome, two had Brown-Sequard syndrome, 12 were injured at too high a level, 42 were injured at too low a level, two were excluded on the basis of motor incompleteness alone, four were excessively denervated, two had limited range of motion, one had overriding medical complications, seven had psychosocial issues making participation impractical, and two elected tendon transfer surgery. In total, 14 patients (representing 11.7% of all tetraplegic individuals and 50% of the C5 or C6 ASIA Impairment Scale A, B or C patients) were found to be candidates for the neuroprosthesis. Given the prevalence of tetraplegia, approximately 12,200 Americans would be candidates for the FES neuroprosthetic hand grasp system under the current research protocols. With both the expansion of current protocols to other diagnostic categories and further research and development, application of this neuroprosthesis to a considerable number of previously excluded subjects will likely be possible.

journal_name

Spinal Cord

journal_title

Spinal cord

authors

Gorman PH,Wuolle KS,Peckham PH,Heydrick D

doi

10.1038/sj.sc.3100460

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

569-73

issue

9

eissn

1362-4393

issn

1476-5624

journal_volume

35

pub_type

临床试验,杂志文章
  • Profile of spinal injuries in Lagos, Nigeria.

    abstract:STUDY DESIGN:Retrospective study. OBJECTIVE:To describe the pattern and outcome of spinal cord injuries in Lagos, Nigeria. SETTING:Nigeria, Lagos. METHODS:This retrospective review of cases was conducted at Lagos University Teaching Hospital (LUTH), Lagos, between January 1992 and December 2006. RESULTS:A total of ...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2008.93

    authors: Obalum DC,Giwa SO,Adekoya-Cole TO,Enweluzo GO

    更新日期:2009-02-01 00:00:00

  • Spinal cord decompression: an endoscopically assisted approach for metastatic tumors.

    abstract:STUDY DESIGN:The paper describes a technique for complete vertebrectomy and spinal cord decompression, followed by a formal anterior column reconstruction, using endoscopic instruments. This procedure is indicated for patients with radioresistant metastasis of the thoracic spine, particularly those involving the upper ...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sj.sc.3101194

    authors: McLain RF

    更新日期:2001-09-01 00:00:00

  • How does knowledge about spinal cord injury-related complications develop in subjects with spinal cord injury? A descriptive analysis in 214 patients.

    abstract:STUDY DESIGN:Monocentric cohort study. OBJECTIVE:To investigate the acquisition of knowledge about spinal cord injury (SCI)-related complications in SCI patients. SETTING:Level 1 trauma center. METHODS:All patients with a traumatic or non-traumatic SCI were included in the study. Data were collected at admission, po...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2010.96

    authors: Thietje R,Giese R,Pouw M,Kaphengst C,Hosman A,Kienast B,van de Meent H,Hirschfeld S

    更新日期:2011-01-01 00:00:00

  • Soft-plastic brace for lower limb fractures in patients with spinal cord injury.

    abstract:STUDY DESIGN:Retrospective study at a rehabilitation center. OBJECTIVES:Patients with spinal cord injury, even if they are wheelchair users, sometimes suffer from fractures of the lower limb bones. As their bones are too weak to have surgery, and because a precise reduction is not required for restoration, such patien...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2012.145

    authors: Uehara K,Akai M,Kubo T,Yamasaki N,Okuma Y,Tobimatsu Y,Iwaya T

    更新日期:2013-04-01 00:00:00

  • MRI of inflammatory spondyloarthropathy following traumatic cauda equina syndrome.

    abstract:BACKGROUND CONTEXT:Spondyloarthropathy has been described radiographically in patients following paralysis from spinal cord trauma. Onset of these findings after cauda equina syndrome have not been reported previously. Furthermore, the magnetic resonance documentation of its early evolution has not been recorded. PURP...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2014.190

    authors: Ginder LM,Porter NA,Subedi N,Singh J,Lalam RK,Tins BJ,Tyrrell PN,Osman A,Cassar-Pullicino VN

    更新日期:2015-03-01 00:00:00

  • Developing a national registry of veterans with spinal cord dysfunction: experiences and implications.

    abstract::We describe the development of a registry of veterans with spinal cord dysfunction who have been treated within the Department of Veterans Affairs health care facilities. The registry departs from the function and structure of traditional registries by a more extensive utilization of advances in computer technology; i...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sj.sc.3100527

    authors: Samsa G,Hoenig H,Carswell J,Sloane R,Bovender CR,VanDeusen Lukas C,Horner RD

    更新日期:1998-01-01 00:00:00

  • The feasibility of using auto-titrating continuous positive airway pressure to treat obstructive sleep apnoea after acute tetraplegia.

    abstract:STUDY DESIGN:A prospective cohort with acute tetraplegia. OBJECTIVES:Obstructive sleep apnoea (OSA) is common within weeks of tetraplegia. This study aimed at determining the feasibility of auto-titrating continuous positive airway pressure (CPAP) to treat OSA after acute tetraplegia. SETTING:The Victorian Spinal Cor...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2009.56

    authors: Berlowitz DJ,Spong J,Pierce RJ,Ross J,Barnes M,Brown DJ

    更新日期:2009-12-01 00:00:00

  • "Challenges and facilitators-navigating in the landscape of spinal cord injury neuropathic pain"-a qualitative study on the use of prescribed drugs.

    abstract:STUDY DESIGN:A qualitative study with an emergent design using semi-structured interviews in focus groups. OBJECTIVES:To explore the expectations, experiences and desires among individuals who are prescribed drugs for spinal cord injury (SCI) neuropathic pain (NP). SETTING:SCI rehabilitation centre. METHODS:Eighteen...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/s41393-020-00553-w

    authors: Norrbrink C,Sörling K,Hultling C,von Kieseritzky F,Wahman K

    更新日期:2020-09-25 00:00:00

  • Bladder cancer in spinal cord injury patients.

    abstract:STUDY DESIGN:Retrospective review. OBJECTIVE:Spinal cord injury is a known risk factor for bladder cancer. The risk of bladder cancer has been reported at 16-28 times higher than the general population. Earlier studies have identified indwelling catheters as risk factors. We examined the characteristics of bladder can...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2009.118

    authors: Kalisvaart JF,Katsumi HK,Ronningen LD,Hovey RM

    更新日期:2010-03-01 00:00:00

  • Tendon transfers in tetraplegic patients: the Cleveland experience.

    abstract::The author has taken care of patients with spinal cord injury for over 30 years. A major part of these years was spent doing tendon transfers on the patients with tetraplegia. Thirteen were not better, but not worse out of the 285 patients who had an operation. All of the patients have had a period of rehabilitation, ...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sj.sc.3100475

    authors: Freehafer AA

    更新日期:1998-05-01 00:00:00

  • Quantitative magnetic resonance imaging analysis correlates with surgical outcome of cervical spondylotic myelopathy.

    abstract:STUDY DESIGN:Prospective study. OBJECTIVES:To investigate whether preoperative and postoperative changes of signal intensity (SI) and transverse area (TA) of the spinal cord reflect the surgical outcome in patients with cervical spondylotic myelopathy (CSM). SETTING:The Second Hospital of Tangshan, Tangshan, Hebei, C...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2014.204

    authors: Sun LQ,Li YM,Wang X,Cao HC

    更新日期:2015-06-01 00:00:00

  • International spinal cord injury endocrine and metabolic extended data set.

    abstract:OBJECTIVE:The objective of this study was to develop the International Spinal Cord Injury (SCI) Endocrine and Metabolic Extended Data Set (ISCIEMEDS) within the framework of the International SCI Data Sets that would facilitate consistent collection and reporting of endocrine and metabolic findings in the SCI populatio...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2016.164

    authors: Bauman WA,Wecht JM,Biering-Sørensen F

    更新日期:2017-05-01 00:00:00

  • rTMS of the prefrontal cortex has analgesic effects on neuropathic pain in subjects with spinal cord injury.

    abstract:STUDY DESIGN:Repetitive transcranial magnetic stimulation study. OBJECTIVES:The analgesic effects of repetitive transcranial magnetic stimulation (rTMS) in chronic pain have been the focus of several studies. In particular, rTMS of the premotor cortex/dorsolateral prefrontal cortex (PMC/DLPFC) changes pain perception ...

    journal_title:Spinal cord

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/sc.2016.87

    authors: Nardone R,Höller Y,Langthaler PB,Lochner P,Golaszewski S,Schwenker K,Brigo F,Trinka E

    更新日期:2017-01-01 00:00:00

  • The treatment of spasticity with Delta9-tetrahydrocannabinol in persons with spinal cord injury.

    abstract:STUDY DESIGN:Open label study to determine drug dose for a randomized double-blind placebo-controlled parallel study. OBJECTIVES:To assess the efficacy and side effects of oral Delta(9)-tetrahydrocannabinol (THC) and rectal THC-hemisuccinate (THC-HS) in SCI patients. SETTING:REHAB Basel, Switzerland. METHOD:Twenty-f...

    journal_title:Spinal cord

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/sj.sc.3101982

    authors: Hagenbach U,Luz S,Ghafoor N,Berger JM,Grotenhermen F,Brenneisen R,Mäder M

    更新日期:2007-08-01 00:00:00

  • Agreement of repeated motor and sensory scores at individual myotomes and dermatomes in young persons with complete spinal cord injury.

    abstract:STUDY DESIGN:Prospective repeated measures. OBJECTIVES:Evaluate intra-rater agreement of repeated motor and sensory scores at individual spinal levels. SETTING:Non-profit pediatric rehabilitation center. METHODS:Fifty-eight youth with complete spinal cord injury undergoing two neurological exams. Agreement between e...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2008.66

    authors: Mulcahey MJ,Gaughan J,Betz RR

    更新日期:2009-01-01 00:00:00

  • Comparative analysis of goal achievement during rehabilitation for older and younger adults with spinal cord injury.

    abstract:OBJECTIVE:To evaluate rehabilitation outcome in a representative sample of older and younger SCI patients. DESIGN:Case series, consecutive sample, survey. SETTING:Tertiary care, spinal cord injury unit (National Spinal Injuries Centre), Stoke Mandeville Hospital. PARTICIPANTS:One hundred and forty-seven male and 45 ...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sj.sc.3101386

    authors: Kennedy P,Evans MJ,Berry C,Mullin J

    更新日期:2003-01-01 00:00:00

  • Correlation of diffusion tensor imaging and phase-contrast MR with clinical parameters of cervical spinal cord injuries.

    abstract:STUDY DESIGN:This is a cross-sectional study. OBJECTIVES:The goal of this study was to characterize the diffusion properties across segments of the spinal cord and peak cerebrospinal fluid (CSF) velocities in the stenotic spinal canal, and to determine the correlation between these properties and clinical and electrop...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2015.57

    authors: Kim SY,Shin MJ,Chang JH,Lee CH,Shin YI,Shin YB,Ko HY

    更新日期:2015-08-01 00:00:00

  • The childbearing experience of women with spinal cord injury in Iran: a phenomenological study.

    abstract:STUDY DESIGN:This was a qualitative study conducted using an interpretative phenomenological approach. OBJECTIVES:This study investigated the experience of pregnancy and childbirth in women with spinal cord injury (SCI). SETTING:Brain and Spinal Cord Injury Research Center, Tehran University of Medical Sciences, Tehr...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/s41393-018-0162-3

    authors: Khazaeipour Z,Nikbakht-Nasrabadi A,Mohammadi N,Salehi-Nejad A,Shabany M

    更新日期:2018-12-01 00:00:00

  • Attentional requirements of postural control in people with spinal cord injury: the effect of dual task.

    abstract:STUDY DESIGN:Cross-sectional study. OBJECTIVES:To investigate the attentional requirements for maintaining standing balance in people with spinal cord injury (SCI) using a dual-task paradigm and to compare standing balance performance between SCI and able-bodied (AB) controls. SETTING:LaboratoryMethods:Nine adults wi...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2017.42

    authors: Tse CM,Carpenter MG,Liu-Ambrose T,Chisholm AE,Lam T

    更新日期:2017-10-01 00:00:00

  • Pediatric spinal cord injury in Sweden; how to identify a cohort of rare events.

    abstract:STUDY DESIGN:Register study enhanced and verified by medical records and personal interviews and examinations. SETTINGS:Sweden. OBJECTIVES:To define a method of identifying a study population of rare events. To point out the relative importance of every step, an example is given of identifying persons who sustained t...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sj.sc.3101456

    authors: Augutis M,Malker H,Levi R

    更新日期:2003-06-01 00:00:00

  • Brown-Séquard-plus syndrome due to stab injury: a case report.

    abstract:STUDY DESIGN:Case report. OBJECTIVE:To describe the mechanism of injury in this case and its clinical features. Magnetic resonance (MR) images of hemorrhage in spinal cord injury due to stab wound are discussed. METHODS:We describe the case of a 21-year-old woman who was stabbed in the right side of her neck and deve...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sj.sc.3101871

    authors: Takemura S,Sasai K,Ohnari H,Ichikawa N,Akagi S,Iida H

    更新日期:2006-08-01 00:00:00

  • Family caregivers of individuals with spinal cord injury: exploring the stresses and benefits.

    abstract:STUDY DESIGN:Cross-sectional, focus group. OBJECTIVES:To explore positive and negative issues reported by family caregivers of people with spinal cord injury (SCI) to develop a relevant and valid tool to assess caregiver distress and benefit for this unique population. METHODS:Seventy-three family caregivers of peopl...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2016.25

    authors: Charlifue SB,Botticello A,Kolakowsky-Hayner SA,Richards JS,Tulsky DS

    更新日期:2016-09-01 00:00:00

  • Application of electrophysiological measures in spinal cord injury clinical trials: a narrative review.

    abstract:STUDY DESIGN:Narrative review. OBJECTIVES:To discuss how electrophysiology may contribute to future clinical trials in spinal cord injury (SCI) in terms of: (1) improvement of SCI diagnosis, patient stratification and determination of exclusion criteria; (2) the assessment of adverse events; and (3) detection of thera...

    journal_title:Spinal cord

    pub_type: 杂志文章,评审

    doi:10.1038/s41393-019-0331-z

    authors: Hubli M,Kramer JLK,Jutzeler CR,Rosner J,Furlan JC,Tansey KE,Schubert M

    更新日期:2019-11-01 00:00:00

  • Therapeutic effects of detrusor botulinum toxin A injection on neurogenic detrusor overactivity in patients with different levels of spinal cord injury and types of detrusor sphincter dyssynergia.

    abstract:STUDY DESIGN:The study was designed as a single-arm clinical trial. OBJECTIVES:To investigate the therapeutic effects of detrusor botulinum toxin A (BoNT-A) treatment in patients with different levels of spinal cord injury (SCI) and types of detrusor sphincter dyssynergia (DSD). SETTING:Patients with chronic suprasac...

    journal_title:Spinal cord

    pub_type: 临床试验,杂志文章

    doi:10.1038/sc.2010.179

    authors: Chen CY,Liao CH,Kuo HC

    更新日期:2011-05-01 00:00:00

  • The effect of tidal volumes on the time to wean persons with high tetraplegia from ventilators.

    abstract:STUDY DESIGN:Retrospective review of patient medical records comparing the outcomes of two groups of individuals with high-level (C3-4) tetraplegia- those with high-volume and those with low-volume mechanical ventilation. OBJECTIVES:To determine if higher volume mechanical ventilation contributes to faster weaning fro...

    journal_title:Spinal cord

    pub_type: 临床试验,杂志文章

    doi:10.1038/sj.sc.3100818

    authors: Peterson WP,Barbalata L,Brooks CA,Gerhart KA,Mellick DC,Whiteneck GG

    更新日期:1999-04-01 00:00:00

  • Assessment of health status in children with spina bifida.

    abstract:STUDY DESIGN:Prospective multidimensional study by means of: (1) clinical assessment, (2) parental-administered questionnaire for general health (CHQ-PF50), and (3) standardised disability measurements. OBJECTIVES:To assess the health-related quality of life (QoL) and disability in children with spina bifida (SB) and ...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sj.sc.3101707

    authors: Rendeli C,Ausili E,Tabacco F,Caliandro P,Aprile I,Tonali P,Salvaggio E,Padua L

    更新日期:2005-04-01 00:00:00

  • Descriptive study of earthquake-related spinal cord injury in Nepal.

    abstract:STUDY DESIGN:Descriptive study. OBJECTIVES:To describe the epidemiological features of spinal cord injury (SCI) following the 2015 earthquakes in Nepal. SETTING:Spinal Injury Rehabilitation Centre, Kavre, Nepal. METHODS:Data were collected from the medical records of all earthquake-related patients seen from 25 Apri...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2017.25

    authors: Groves CC,Poudel MK,Baniya M,Rana C,House DR

    更新日期:2017-07-01 00:00:00

  • The efficacy of biochemical markers in patients with ossification of posterior longitudinal ligament of the spine.

    abstract:STUDY DESIGN:Serum levels of carboxyterminal propeptide of type I collagen (PICP), osteocalcin (OC), carboxyterminal telopeptide of type I collagen (ICTP) and urinary levels of pyridinoline (Pyr) and deoxypyridinoline (Dpyr) were measured in patients with ossification of posterior longitudinal ligament of the spine (OP...

    journal_title:Spinal cord

    pub_type: 临床试验,杂志文章

    doi:10.1038/sj.sc.3100989

    authors: Ishihara C,Kushida K,Takahashi M,Ohishi T,Murata H,Nagano A,Goto S

    更新日期:2000-04-01 00:00:00

  • Dual-energy X-ray absorptiometry overestimates bone mineral density of the lumbar spine in persons with spinal cord injury.

    abstract:BACKGROUND:Bone mineral density (BMD) of the lumbar spine (L-spine) has been reported to be normal or increased in persons with chronic spinal cord injury (SCI). OBJECTIVE:To determine BMD of the L-spine by dual-energy X-ray absorptiometry (DXA) and quantitative computerized tomography (qCT) in men with chronic SCI co...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/sc.2008.169

    authors: Bauman WA,Schwartz E,Song IS,Kirshblum S,Cirnigliaro C,Morrison N,Spungen AM

    更新日期:2009-08-01 00:00:00

  • Clinical indicators of surgical outcomes after cervical single open-door laminoplasty assessed by the Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire.

    abstract:STUDY DESIGN:Retrospective cohort study. OBJECTIVES:The old-version JOA score for cervical myelopathy (CM) is an evaluation system performed by medical providers that focuses only on neurological function. The purpose of this study was to evaluate patient-reported outcomes using the Japanese Orthopaedic Association Ce...

    journal_title:Spinal cord

    pub_type: 杂志文章

    doi:10.1038/s41393-019-0258-4

    authors: Nagoshi N,Tsuji O,Okada E,Fujita N,Yagi M,Tsuji T,Nakamura M,Matsumoto M,Watanabe K

    更新日期:2019-08-01 00:00:00