Abstract：
STUDY DESIGN:Serum levels of carboxyterminal propeptide of type I collagen (PICP), osteocalcin (OC), carboxyterminal telopeptide of type I collagen (ICTP) and urinary levels of pyridinoline (Pyr) and deoxypyridinoline (Dpyr) were measured in patients with ossification of posterior longitudinal ligament of the spine (OPLL) and age-matched control subjects. OBJECTIVES:To evaluate the efficacy of these biochemical markers of the patients with OPLL. SETTING:Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan. METHODS:Spot urine and blood samples were obtained from 20 healthy males aged 45 - 78 (mean+/-SD; 63. 0+/-11.5) and 22 male patients with OPLL aged 46 - 77 (mean+/-SD; 59. 9+/-8.8), and serum levels of PICP, OC, ICTP and urinary levels of Pyr and Dpyr were measured. RESULTS:There were no significant difference in age, serum PICP, OC, ICTP, urinary Pyr and Dpyr levels between OPLL and control group. CONCLUSION:Neither bone formation nor bone resorption was accelerated in the patients with OPLL.
journal_name
Spinal Cordjournal_title
Spinal cordauthors
Ishihara C,Kushida K,Takahashi M,Ohishi T,Murata H,Nagano A,Goto Sdoi
10.1038/sj.sc.3100989subject
Has Abstractpub_date
2000-04-01 00:00:00pages
211-3issue
4eissn
1362-4393issn
1476-5624journal_volume
38pub_type
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