Abstract：
STUDY DESIGN:Retrospective review of consecutive cases of recurrent spinal cord and cauda equina tumours. OBJECTIVES:We sought to identify factors and conditions resulting in re-operation to treat recurrences of spinal cord and cauda equina tumours. SETTING:Keio University Hospital, Tokyo, Japan. METHODS:Re-operation was performed in 39 patients with spinal cord and cauda equina tumours. Times of operation, interval between operations, affected spinal level, tumour site on cross section, configurations among dumb-bell tumours, and pathologic diagnoses were analysed. Recurrence rates were defined in terms of the number of cases with re-operation due to tumour recurrence relative to the total number of surgical cases for the same period at our institution. RESULTS:Recurrence rates were relatively high for intradural, extramedullary tumours and for tumours located anteriorly rather than laterally. Of patients with intradural, extramedullary plus extradural tumours who underwent initial surgery at our hospital, 75% (9/12) recurred; all tumours had dumb-bell-type configurations. The overall rate of re-operation due to tumour recurrence in 249 cases was 7.2% at our institution. By tumour types, 40% of malignant schwannomas recurred (2/5), as did 35.7% of neurofibromas (5/14), and 33.3% of ependymomas (6/18). CONCLUSION:Risk factors for tumour recurrence were anterior location, an intradural, extramedullary plus extradural site, extensive dumb-bell tumours, and pathologic diagnoses of neurofibroma, ependymoma, or malignant schwannoma.
journal_name
Spinal Cordjournal_title
Spinal cordauthors
Asazuma T,Toyama Y,Watanabe M,Suzuki N,Fujimura Y,Hirabayashi Kdoi
10.1038/sj.sc.3101394subject
Has Abstractpub_date
2003-02-01 00:00:00pages
85-9issue
2eissn
1362-4393issn
1476-5624pii
3101394journal_volume
41pub_type
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