Abstract:
STUDY DESIGN:Multicenter prospective cohort. OBJECTIVE:To discern neurological- and functional recovery in patients with a traumatic thoracic spinal cord injury (TSCI), conus medullaris syndrome (CMS), and cauda equina syndrome (CES). SETTING:Specialized spinal cord injury centers in Europe. METHOD:Lower extremity motor score (LEMS) and spinal cord independent measure (SCIM) scores from patients with traumatic TSCI, CMS, and CES were extracted from the EMSCI database. Scores from admittance and during rehabilitation at 1, 3, 6, and 12 months were compared. Linear mixed models were used to statistically analyse differences in outcome, which were corrected for the ASIA Impairment Scale (AIS) in the acute phase. RESULTS:Data from 1573 individuals were analysed. Except for the LEMS in patients with a CES AIS A, LEMS, and SCIM significantly improved over time for patients with a TSCI, CMS, and CES. Irrespectively of the AIS score, recovery in 12 months after trauma as measured by the LEMS showed a statistically significant difference between patients with a TSCI, CMS, and CES. Analysis of SCIM score showed no difference between patients with TSCI, CMS, or CES. CONCLUSION:Difference in recovery between patients with a traumatic paraplegia is based on neurological (motor) recovery. Regardless the ceiling effect in CES patients, patients with a mixed upper and lower motor neuron syndrome (CMS) showed a better recovery compared with patients with a upper motor neuron syndrome (TSCI). These findings enable stratifications of patients with paraplegia according to the level and severity of SCI.
journal_name
Spinal Cordjournal_title
Spinal cordauthors
Brouwers EMJR,Meent HV,Curt A,Maier DD,Abel RF,Weidner N,Rupp R,Kriz J,de Haan AFJ,Kramer JK,Hosman AJF,Bartels RHMA,EMSCI participants and investigators.doi
10.1038/s41393-020-0463-1subject
Has Abstractpub_date
2020-09-01 00:00:00pages
980-987issue
9eissn
1362-4393issn
1476-5624pii
10.1038/s41393-020-0463-1journal_volume
58pub_type
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