A randomized controlled trial of fluoxetine and cognitive behavioral therapy for bulimia nervosa: short-term outcome.

Abstract:

:This study compared and combined fluoxetine and individual cognitive behavioral therapy in the treatment of bulimia nervosa. Participants were 76 women who sought treatment at the Eating Disorders Program of the Toronto Hospital and who met DSM-III-R criteria for bulimia nervosa. Subjects were randomly assigned to receive fluoxetine alone, cognitive behavior therapy alone, or the two in combination and were treated over 16 weeks. Short-term outcome revealed that all three treatment conditions were associated with clinical improvement across a wide range of parameters. The combination of pharmacotherapy and psychotherapy was superior to pharmacotherapy alone on specific parameters and there was no statistically significant advantage to the combination over psychotherapy alone. Limitations to the study include the absence of a placebo pill group and a waiting list control group as well as a substantial dropout rate across all three treatment conditions.

journal_name

Behav Res Ther

authors

Goldbloom DS,Olmsted M,Davis R,Clewes J,Heinmaa M,Rockert W,Shaw B

doi

10.1016/s0005-7967(97)00041-7

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

803-11

issue

9

eissn

0005-7967

issn

1873-622X

pii

S0005-7967(97)00041-7

journal_volume

35

pub_type

临床试验,杂志文章,随机对照试验
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