Abstract：
BACKGROUND:Depression and anxiety disorders are relapse-prone conditions, even after successful treatment with pharmacotherapy or psychotherapy. Cognitive behavioural therapy (CBT) is known to prevent relapse, but there is little evidence of the durability of remission after low intensity forms of CBT (LiCBT). METHOD:This study aimed to examine relapse rates 12 months after completing routinely-delivered LiCBT. A cohort of 439 LiCBT completers with remission of symptoms provided monthly depression (PHQ-9) and anxiety (GAD-7) measures during 12 months after treatment. Survival analysis was conducted to model time-to-relapse while controlling for patient characteristics. RESULTS:Overall, 53% of cases relapsed within 1 year. Of these relapse events, the majority (79%) occurred within the first 6 months post-treatment. Cases reporting residual depression symptoms (PHQ-9 = 5 to 9) at the end of treatment had significantly higher risk of relapse (hazard ratio = 1.90, p < 0.001). CONCLUSIONS:The high rate of relapse after LiCBT highlights the need for relapse prevention, particularly for those with residual depression symptoms.
journal_name
Behav Res Therjournal_title
Behaviour research and therapyauthors
Ali S,Rhodes L,Moreea O,McMillan D,Gilbody S,Leach C,Lucock M,Lutz W,Delgadillo Jdoi
10.1016/j.brat.2017.04.006subject
Has Abstractpub_date
2017-07-01 00:00:00pages
1-8eissn
0005-7967issn
1873-622Xpii
S0005-7967(17)30084-0journal_volume
94pub_type
临床试验,杂志文章abstract：:The aim of this study was to investigate the effect of mindfulness-based stress reduction (MBSR) for patients with heterogeneous anxiety disorders. Seventy-six self-referred patients were randomized to MBSR or a waiting-list control condition. Eight participants did not complete the eight-week MBSR intervention. Treat...
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