The anatomy and cell biology of peripheral myelin protein-22.

Abstract:

:The gain of function phenotypes exhibited by the heterozygous Tr, Tr-J, and CMT1A mutations indicate that these mutations interfere with more than the function of a single PMP22 allele. The identification of proteins that interact with PMP22 and that are sensitive both to stoichiometry and the effects of the mutations could provide important leads to a unified hypothesis to explain the riddle of the PMP22-related neuropathies.

journal_name

Ann N Y Acad Sci

authors

Snipes GJ,Orfali W,Fraser A,Dickson K,Colby J

subject

Has Abstract

pub_date

1999-09-14 00:00:00

pages

143-51

eissn

0077-8923

issn

1749-6632

journal_volume

883

pub_type

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