Abstract：
:Seven pure flavonoids were isolated and identified from five moss species. The flavonoids were the flavones apigenin, apigenin-7-O-triglycoside, lucenin-2, luteolin-7-O-neohesperidoside, saponarine and vitexin; and the biflavonoid bartramiaflavone. Some of these flavonoids were shown to have pronounced antibacterial effects against Enterobacter cloaceae, E. aerogenes and Pseudomonas aeruginosa (minimal bacteriostatic concentration MIC in the range of 4-2048 micrograms/ml). Because of their antibacterial spectrum mainly active against Gram negative bacterial strains, responsible for severe opportunistic infections and resistant to common antibacterial therapy, these flavonoids may be important tools in antibacterial strategies.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Basile A,Giordano S,López-Sáez JA,Cobianchi RCdoi
10.1016/s0031-9422(99)00286-1subject
Has Abstractpub_date
1999-12-01 00:00:00pages
1479-82issue
8eissn
0031-9422issn
1873-3700pii
S0031-9422(99)00286-1journal_volume
52pub_type
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