Retinoblastoma in adults. Report of three cases and review of the literature.

Abstract:

:Retinoblastoma usually presents in children younger than 5 years. To our knowledge, 20 cases of retinoblastoma in adults (older than 20 years) have been reported in the literature. Of 173 patients with histopathologically proven retinoblastoma seen in our institute, three were adults. All the patients had endophytic tumors with vitreous seeds. Ultrasonography did not reveal calcification in two cases. Immunohistochemistry with neuron-specific enolase was used to confirm the diagnosis in two cases. All three patients ultimately required enucleation. None of the patients had been referred with a diagnosis of retinoblastoma. The diagnosis of retinoblastoma should be considered in cases of whitish mass lesion in the fundus of an adult.

journal_name

Surv Ophthalmol

journal_title

Survey of ophthalmology

authors

Biswas J,Mani B,Shanmugam MP,Patwardhan D,Kumar KS,Badrinath SS

doi

10.1016/s0039-6257(99)00132-0

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

409-14

issue

5

eissn

0039-6257

issn

1879-3304

pii

S0039-6257(99)00132-0

journal_volume

44

pub_type

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