Abstract:
:The relationship between gallbladder (GB) bile concentration and motility was studied in conscious dogs. The 12-h GB bile concentrations between meals could be divided into three periods: diluting, minimum, and concentrating periods. During the diluting period, inhibition of GB contractions by a CCKA receptor antagonist, atropine or hexamethonium, resulted in concentration of GB bile, whereas during the concentrating period, CCK-8 shifted the concentration process back to dilution. The GB appears to absorb water continuously from GB bile, which is not regulated by cholinergic or CCKA receptors. The postprandial progressive dilution of GB bile is brought about by GB pumping controlled by cholecystokinin (CCK).
journal_name
Peptidesjournal_title
Peptidesauthors
Muramatsu S,Sonobe K,Mizumoto A,Yamada T,Itoh Zdoi
10.1016/s0196-9781(96)00247-1subject
Has Abstractpub_date
1997-01-01 00:00:00pages
111-8issue
1eissn
0196-9781issn
1873-5169pii
S0196-9781(96)00247-1journal_volume
18pub_type
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