Abstract:
:We used 2.15 to 2.3% collodion in amyl acetate to form a replica of the corneal surface epithelium in vivo in seven rabbit eyes and ten human eyes. When it was peeled off the replica removed superficial epithelial cells in patches. The corneal epithelium regenerated within one week. Repeated applications at weekly intervals for three months produced no harmful long-term effects in five rabbit corneas as evaluated with slit-lamp biomicroscopy, histological methods, and vital staining of the endothelium. In ten human eyes, the technique was harmless and chemically cauterized the dendritic herpetic ulcers. We studied the replicas and cells by conventional histological methods and electron microscopy. The preservation of cells was fairly good even for ultrastructural study.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Missotten L,Maudgal PCdoi
10.1016/0002-9394(77)90333-6subject
Has Abstractpub_date
1977-07-01 00:00:00pages
104-11issue
1eissn
0002-9394issn
1879-1891pii
0002-9394(77)90333-6journal_volume
84pub_type
杂志文章abstract:PURPOSE:To investigate ocular involvement (prevalence, incidence, lesion characteristics) following postnatally acquired infection with an "atypical" genotype of Toxoplasma gondii during a well-characterized 2001 outbreak in Santa Isabel do Ivaí, Brazil, attributed to a contaminated municipal reservoir. DESIGN:Prospec...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.02.017
更新日期:2015-06-01 00:00:00
abstract::The effect of rapid freezing and thawing was tested in vitro on 100 human hard nuclear cataracts before ultrasonic emulsification. After phacocryolysis the interspace between lens fibers increased, and the normally closely packed fibers appeared to loosen. This seemed to soften the hard cataract, thereby facilitating ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(77)90906-0
更新日期:1977-06-01 00:00:00
abstract::We observed a 41-year-old man with congenital unilateral iris pigment epithelial hyperplasia associated with unilateral glaucoma, and considered the possible pathogenesis of this unique lesion and its relationship to the patient's glaucoma. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)76809-6
更新日期:1978-08-01 00:00:00
abstract:PURPOSE:To determine whether central corneal thickness (CCT) is a risk factor for visual field loss development among patients diagnosed with preperimetric glaucomatous optic neuropathy (GON). DESIGN:Observational cohort study. METHODS:The study included 98 eyes of 98 patients with GON, with a mean follow-up time of ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00484-7
更新日期:2003-11-01 00:00:00
abstract::To study the retinal surface in the human eye in normal and diseased states we used laser scanning tomography. The confocal arrangement of the laser tomographic scanner permits examination of retinal topography in the axis perpendicular to the retinal surface. The eyes examined with the laser tomographic scanner inclu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(89)90118-9
更新日期:1989-09-15 00:00:00
abstract:PURPOSE:To report the clinical and histological findings of a luxated intraocular lens (IOL) in the capsular bag. METHODS:Review of a case. RESULTS:Twenty-three months after a triple procedure of vitrectomy, phacoemulsification, and IOL implantation for diabetic vitreous hemorrhage and cataract, the encapsulated IOL ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00630-9
更新日期:2000-12-01 00:00:00
abstract:PURPOSE:To identify factors related to graft rejection following Descemet stripping automated endothelial keratoplasty (DSAEK) in the Cornea Preservation Time Study (CPTS). DESIGN:Cohort study within a multicenter randomized clinical trial. METHODS:A total of 1330 eyes of 1090 subjects undergoing DSAEK were randomize...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2018.10.005
更新日期:2018-12-01 00:00:00
abstract::A patient with X-chromosome-linked recessive Norrie's disease, characterized by retinal falciform fold, retinal detachment, repeated vitreous hemorrhage, and retrolental membrane formation, was observed from age 6 weeks. The patient showed the clinical progression from these early retinal and vitreous changes to the m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75079-2
更新日期:1980-07-01 00:00:00
abstract:PURPOSE:To evaluate the anatomic and visual outcomes in patients with initially closed macular holes after vitreoretinal surgery and with 1 to 7 years of follow-up. DESIGN:Retrospective, noncomparative, consecutive case series. METHODS:Eighty-seven consecutive eyes of 79 patients with previous closure of the macular ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.11.006
更新日期:2011-05-01 00:00:00
abstract::A retrospective study of 23 conjunctival melanomas using the Clark classification revealed that the three most common forms of melanoma described in the skin--lentigo maligna melanoma (Hutchinson's freckle with melanoma), superficial spreading melanoma, and nodular melanoma--can be recognized in the conjunctiva. As in...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90487-6
更新日期:1976-09-01 00:00:00
abstract::Nine patients with polyradiculomyeloneuropathy after acute hemorrhagic conjunctivitis (AHC) infection were studied serologically. All except one patient had neutralization titers larger than or equal to 1:16 against the prototype J670/71 strain of AHC virus in at least one of their serum samples. The development of a ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90279-2
更新日期:1975-11-01 00:00:00
abstract:PURPOSE:To determine the regional differences in the test-retest variability of topographic measurements of the optic nerve head obtained with a confocal scanning laser retina tomograph. METHODS:Three 10-degree topographic images centered on the optic disk of 20 individuals (20 eyes), five normal subjects, seven glauc...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72656-x
更新日期:1995-10-01 00:00:00
abstract:PURPOSE:To investigate the complication profile and the long-term functional outcome of combined pars plana vitrectomy and scleral-fixated sutured posterior chamber lens (PC IOL) implantation. DESIGN:Retrospective, consecutive, interventional case series. METHODS:The records of 63 patients (mean age, 67.5 years) were...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.05.014
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:To characterize crystalline lens dimensions derived from in-vivo spectral-domain optical coherence tomography (SD-OCT) and identify associations between these parameters, ocular biometry and age. METHODS:In this retrospective study, lens thickness (LT), lens diameter (LD) and lens volume (LV) were measured int...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.12.021
更新日期:2020-12-29 00:00:00
abstract:PURPOSE:To report endoscopic findings in the anterior chamber angle during injection of viscoelastic material in viscocanalostomy (VCS). DESIGN:Observational case reports. METHODS:Two cases of primary open-angle glaucoma were treated with VCS and cataract surgery. Immediately before and during injection of viscoelast...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.06.040
更新日期:2004-12-01 00:00:00
abstract::A 3 1/2-month-old boy with the cerebro-oculo-facio-skeletal syndrome had low birth weight, microcephaly, microphthalmia, cataracts, blepharophimosis, high nasal bridge, micrognathia, kyphosis, rocker-bottom feet, and a longitudinal foot groove. The product of a consanguineous parentage, he showed marked developmental ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90127-0
更新日期:1980-02-01 00:00:00
abstract::A 2,000-g infant boy had many features of the Smith-Lemli-Opitz syndrome (prenatal growth deficiency and developmental retardation, microcephaly with unusual facies, hypospadias, and feeding difficulties) as well as sclerocornea. The association of this rare eye finding with this rare congenital syndrome is unique. Su...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(77)90327-0
更新日期:1977-07-01 00:00:00
abstract:PURPOSE:To assess whether successful surgical intervention for intermittent exotropia, or the timing of intervention, has any effect on the development of mental illness. DESIGN:Retrospective, observational case series. METHODS:All patients (<19 years of age) diagnosed with intermittent exotropia in Olmsted County, M...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.06.008
更新日期:2014-10-01 00:00:00
abstract::A 50-year-old man sustained severe head injury, including a brief loss of consciousness, in an automobile accident. Skull X-ray films disclosed a fracture of the right superior orbit. Computed tomography demonstrated pneumocephalus and extension of the fracture into the sella turcica. Perimetric testing disclosed a bi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90778-9
更新日期:1981-08-01 00:00:00
abstract::We developed a method that models the effect of irregular corneal surface topography on corneal optical performance. A computer program mimics the function of an optical bench. The method generates a variety of objects (single point, standard Snellen letters, low contrast Snellen letters, arbitrarily complex objects) ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74602-1
更新日期:1990-04-15 00:00:00
abstract:PURPOSE:To characterize the progression of optical gaps and expand the known etiologies of this phenotype. DESIGN:Retrospective cohort study. METHODS:Thirty-six patients were selected based on the identification of an optical gap on spectral-domain optical coherence tomography (OCT) from a large cohort of patients (N...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.016
更新日期:2020-10-01 00:00:00
abstract::Acetazolamide's usefulness in the treatment of the glaucomas is limited by the systemic side effects that often accompany its oral administration, and topical administration was initially thought to have no effect upon the intraocular pressures of human and rabbit eyes. Recent studies, however, have shown the usefulne...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(84)90190-9
更新日期:1984-07-15 00:00:00
abstract:PURPOSE:To determine a possible correlation specifically between hemoglobin A1C (HgbA1C) levels and the presence and severity of retinopathy during diabetic eye screening. DESIGN:Retrospective medical record review of all new patients examined in a Veteran Affairs Medical Center (VAMC) diabetic screening clinic in 200...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.04.008
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:To investigate the natural history of Stargardt disease (STGD1) using fixation location and fixation stability. DESIGN:Multicenter, international, prospective cohort study. METHODS:Fixation testing was performed using the Nidek MP-1 microperimeter as part of the prospective, multicenter, natural history study...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2018.06.003
更新日期:2018-09-01 00:00:00
abstract::We conducted electrophysiologic tests of the toxic effects of fluorouracil on 26 albino rabbit eyes. Fluorouracil concentrations of 10(-7) g/ml, 10(-6) g/ml, and 10(-5) g/ml produced no significant changes in the b-wave amplitudes of the electroretinogram. A concentration of 10(-4) g/ml, however, reduced the b-wave am...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73422-1
更新日期:1983-11-01 00:00:00
abstract:PURPOSE:To report a group of patients with symptoms of pain, strabismus, sensation of orbital fullness, and presence of a subconjunctival mass many years after successful scleral buckling surgery using hydrogel explants. DESIGN:We present an interventional consecutive case series of patients who underwent scleral buck...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00873-0
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To analyze the comparative safety and efficacy of two techniques of corneal neurotization (CN) (direct corneal neurotization [DCN] vs indirect corneal neurotization [ICN]) for the treatment of neurotrophic keratopathy (NK). DESIGN:Multicenter interventional prospective comparative case series. METHODS:This st...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2020.07.003
更新日期:2020-12-01 00:00:00
abstract::We conducted a prospective randomized clinical trial on the use of 2% hydroxypropyl methylcellulose and 1% sodium hyaluronate in the anterior chamber during anterior capsulotomy and nuclear expression in extracapsular cataract extraction with posterior chamber lens implantation in 70 patients. Both viscoelastic substa...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-9394(86)90399-5
更新日期:1986-12-15 00:00:00
abstract:PURPOSE:To report a physician survey, laboratory studies, and clinical observations of intraoperative crystallization on the surface of the intraocular lens (IOL). METHOD:We sent a survey to all ophthalmologists in the states of Wyoming, Idaho, Montana, Utah, and Colorado asking whether crystallization on the IOL surf...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00076-2
更新日期:1998-08-01 00:00:00
abstract:PURPOSE:To compare immunocytochemical and ultrastructural characteristics of "lamellar hole-associated epiretinal proliferation" in lamellar macular holes with "conventional epiretinal membrane" in macular pseudoholes. DESIGN:A consecutive observational case series, laboratory investigation. METHODS:We analyzed surgi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.05.010
更新日期:2015-08-01 00:00:00