Chlamydia trachomatis as a possible cofactor for Kaposi's sarcoma in AIDS.

Abstract:

:AIDS-associated Kaposi's sarcoma (KS) is much more frequent in patients acquiring HIV infection via the sexual route. Epidemiological studies have confirmed the likely involvement of a sexually acquired cofactor in the pathogenesis of this form of KS. We have formulated a set of postulates, epidemiological and experimental, to fit a single unifying hypothetical agent. Chlamydia trachomatis is one of 3 agents to fit the epidemiological criteria. Our data suggest a possible association between increased IgG serum antibody to C. trachomatis and the occurrence of KS. Conversely, higher titres of IgG serum antibody to C. pneumoniae were associated with the absence of KS. We feel that it is important to study further the relationship between C. trachomatis and KS.

journal_name

Int J STD AIDS

authors

Peters BS,Thomas BJ,Yi C,Beck EJ,Weber J,Pinching AJ,Taylor-Robinson D

doi

10.1177/095646249500600609

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

422-5

issue

6

eissn

0956-4624

issn

1758-1052

journal_volume

6

pub_type

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