Abstract:
:The need for salvage treatment is related to the imperfection of current antiretroviral therapy. Sequential therapy with suboptimally suppressive regimens results in a need for this intervention. The aim of salvage treatment is as yet uncertain; virological suppression; immunoenhancement or stability or avoidance of clinical disease. Therapeutic options are constantly improving and the knowledge base concerning individual agents and different combinations comprising highly active antiretroviral treatment (HAART) regimens increases daily. The utility of new agents in salvage appears vital with numbers of new or recycled agents to which no demonstrable resistance exists is a major predictive factor of a positive outcome in this setting. Patient commitment, physician knowledge and an informed supportive environment are also conducive to success in salvage treatment.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Youle Mdoi
10.1258/0956462011923093subject
Has Abstractpub_date
2001-05-01 00:00:00pages
286-94issue
5eissn
0956-4624issn
1758-1052journal_volume
12pub_type
杂志文章,评审abstract::A recent survey reported that 36% of UK genitourinary medicine clinics offer testing for pharyngeal Chlamydia trachomatis (CT). Screening at this site is targeted at high-risk groups attending our centre, including female sex workers (FSWs) and male sex workers (MSWs). A total of 2406 patients were screened between No...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.009494
更新日期:2010-11-01 00:00:00
abstract::Previous studies have reported an inverse relationship between condom use and emotional intimacy. The aim of this study was to determine the relationship between condom use and emotional intimacy. The study was a gonorrhoea case-comparison study with the samples being drawn from public health clinics (cases) and selec...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009238
更新日期:2009-11-01 00:00:00
abstract::Although important, the foreskin is not absolutely essential to penile function. Dysfunction is common and a cause of considerable morbidity, and is sometimes associated with mortality from squamous cell carcinoma (SCC). Penile dermatoses herald, complicate or cause preputial dysfunction. Their effective diagnosis and...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/0956462011922922
更新日期:2001-04-01 00:00:00
abstract::Women attending a dedicated medical gynaecology and family planning referral clinic for women with HIV were surveyed using a standard questionnaire about their knowledge and attitudes to post-exposure prophylaxis after sexual exposure (PEPSE) and emergency hormonal contraception (EHC). Eighty percent of them had not h...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007159
更新日期:2008-01-01 00:00:00
abstract::Public health authorities have long believed that the preponderance of AIDS cases in Africa are attributable to 'heterosexual transmission'; most people silently assume this rubric to indicate penile-vaginal intercourse only. Recent epidemiologic analyses suggest that the majority of HIV cases in sub-Saharan Africa ma...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646203322025704
更新日期:2003-07-01 00:00:00
abstract::The expense in time and money limit the use of randomized clinical trials (RCT) and cohort studies for evaluating long-term AIDS treatment outcomes. We conducted a case-control study to characterize predictors of AIDS mortality after the availability of highly active antiretroviral therapy (HAART) in San Francisco, in...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008381
更新日期:2009-05-01 00:00:00
abstract::Haematogenous dissemination of undiagnosed urinary tuberculosis after performing extracorporeal shock-wave lithotripsy (ESWL) is extremely rare. Herein, we report a 41-year-old male who presented with urosepsis to the emergency room; catheterization was performed and retention resolved. He had a tattoo on his left arm...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413498580
更新日期:2014-03-01 00:00:00
abstract::Household contacts of hepatitis B (HBV) are at risk of infection, and guidelines advise vaccination of these contacts in addition to sexual partners (along with traditional high-risk groups). We present a case of intrafamilial transmission of acute hepatitis B virus (HBV) following failure to self-disclose status to f...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009482
更新日期:2011-11-01 00:00:00
abstract::Ninety women who were HIV antibody positive attended the genitourinary medicine clinics of East Riverside up to May 1990. Seventy-five of these women (83%) were examined for co-existent sexually transmitted disease (STD) at presentation. The prevalence of STD in these women was compared to the incidence of STD in all ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200312
更新日期:1991-05-01 00:00:00
abstract::To determine the frequency, imaging characteristics, neuroanatomical distribution and dynamics of magnetic resonance imaging findings in HIV-associated cryptococcal meningitis in immunocompromised patients we compared patients without antiretroviral therapy with patients undergoing immune reconstitution. Neuroimaging ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415574633
更新日期:2016-02-01 00:00:00
abstract::Herpes simplex virus type 2 (HSV-2) HIV co-infection is common and associated with increased risk of HIV transmission. HSV-2 seroprevalence was assessed on stored samples from baseline and one year follow-up from 81 patients identified with acute HIV infection and 81 age-matched chronically infected men. HSV-2 seropre...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010551
更新日期:2011-08-01 00:00:00
abstract::Squamous cell carcinoma of the penis is an uncommon cancer, though in one study it accounted for 90% of all penile cancers. Its association with balanitis xerotica obliterans (BXO) is a rare though recognized occurrence. We describe a case of a 46-year-old Caucasian male who first presented to our open-access clinic w...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206775455658
更新日期:2006-02-01 00:00:00
abstract::Paradoxical reactions, including immune reconstitution inflammatory syndrome (IRIS), are common in patients co-infected with human immunodeficiency virus (HIV) and tuberculosis (TB). Paradoxical reactions may confer substantial morbidity and mortality, especially in cases of central nervous system (CNS) TB, or through...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420915394
更新日期:2020-07-01 00:00:00
abstract::Using data from TREAT Asia HIV Observational Database (TAHOD), this paper aims to assess the rate of, and factors associated with the diagnosis of new AIDS-defining illness (ADI) within 90 days after antiretroviral treatment. Patients starting three or more antiretroviral combinations and having subsequent follow-up w...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207781147283
更新日期:2007-07-01 00:00:00
abstract::HIV seroconversions and sexually transmitted diseases (STDs) are often clustered in social networks within community populations. The present study was carried out among men who have sex with men in Russia, where a major HIV epidemic is unfolding, and where social networks have played a historically important role. In...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206775220504
更新日期:2006-01-01 00:00:00
abstract::We report a case series of HIV/HCV co-infected patients who underwent preemptive antiretroviral therapy modifications to manage clinically significant drug interactions with HCV therapy. Among the 15 patients reviewed, all changed to a raltegravir-based regimen and none experienced a loss of virologic suppression or i...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415580225
更新日期:2016-03-01 00:00:00
abstract::This study compared the distributions of known human immunodeficiency virus (HIV) and acute hepatitis B virus (HBV) infection among drug injectors in Glasgow over a 3.5 year period. Data were obtained from all relevant laboratory request forms submitted to Glasgow's 3 virology laboratories during the period 1 January ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200509
更新日期:1991-09-01 00:00:00
abstract::Due to demographic changes in people living with HIV (PLHIV), physicians are challenged with age-related comorbidities and their management. In the absence of comprehensive data collection, the burden of comorbidities and co-medication in addition to antiretroviral therapy (ART) remains unclear for the German real-wor...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420942020
更新日期:2020-12-15 00:00:00
abstract::Summary HIV transmission risk is increased during antiretroviral therapy (ART) use if individuals are not virologically suppressed and engage in high risk transmission behaviour. Baseline data of HIV-infected men who have sex with men (MSM) with recent history of risky behaviour on ART for ≥3 months (n = 139) were eva...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413518500
更新日期:2014-09-01 00:00:00
abstract::Perceived health-related quality of life (QOL) of 113 adult people living with HIV/AIDS (PHA) attending an outpatient hospital clinic was assessed upon initial registration using the Medical Outcomes Study SF-36. QOL ratings on both physical functioning and psychological well-being aspects of the SF-36 were lower than...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011923598
更新日期:2001-08-01 00:00:00
abstract::In a study to determine the herpes simplex virus (HSV) type isolated from patients with primary (first-attack) genital herpes and to identify any clinical or epidemiological features that might influence the reported incidence of any particular viral type, there was almost an equal incidence of HSV-1 and HSV-2 isolate...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249000100306
更新日期:1990-05-01 00:00:00
abstract::Peripheral neuropathy is one of the most common neurological complications of HIV infection with a 30-60% lifetime prevalence. Newer HIV drugs cause less peripheral neuropathy, but patients are now living long enough to develop concomitant diabetes-related, vascular-related, and chemotherapy-related neuropathy so it c...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416656688
更新日期:2017-02-01 00:00:00
abstract::The HIV epidemic in Vietnam is concentrated, with high prevalence estimates among injection drug users and commercial sex workers. Socio-demographics, substance use and clinical correlates of antiretroviral therapy non-adherence were studied in 100 HIV-1 infected drug users receiving antiretroviral therapy for at leas...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413516301
更新日期:2014-08-01 00:00:00
abstract::The prevalence of urogenital infection caused by Chlamydia trachomatis was examined in 100 non-pregnant women with cervicitis, and 100 healthy women, in San Salvador City, El Salvador. Pharmacia Chlamydia EIA test was used for the detection of chlamydial antigen in urethral and cervical specimens from all the women. D...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249200300607
更新日期:1992-11-01 00:00:00
abstract::We aim to clarify the prevalence of Mycoplasma genitalium in asymptomatic men in Japan. First-catch urine specimens were obtained from 187 asymptomatic Japanese men and examined for the presence of M. genitalium using a polymerase chain reaction (PCR)-based assay. Two (1.1%) of 187 first-catch urine specimens were pos...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971919877
更新日期:1997-04-01 00:00:00
abstract::The purpose of this study was to investigate whether Epstein-Barr virus (EBV) is associated with acetowhite lesions of the portio cervix, demonstrating koilocytosis and/or cervical intraepithelial neoplasia (CIN) I-III. The study group comprised 37 women admitted to the Department of Gynaecology and Obstetrics, Sahlgr...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971920488
更新日期:1997-07-01 00:00:00
abstract::Summary Comprehensive testing for asymptomatic sexually transmitted infections in Northern Ireland has traditionally been provided by genitourinary medicine clinics. As patient demand for services has increased while budgets have remained limited, there has been increasing difficulty in accommodating this demand. In M...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413519430
更新日期:2014-09-01 00:00:00
abstract::We describe a case of cryptococcal meningitis in a patient known to have HIV who presented initially with ocular cryptococcosis. This case highlights to clinicians the need to be aware of this association and to carry out relevant investigations so as to treat these patients appropriately. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2009.009132
更新日期:2012-05-01 00:00:00
abstract::Raltegravir is one of the standard antiretroviral therapy (ART) options in treatment-experienced and -naïve patients. However, efficacy data from clinical practice are scarce. Therefore, the efficacy of raltegravir-containing ART in clinical practice was investigated retrospectively. In all, 295 treatment-naïve and -e...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415610678
更新日期:2016-11-01 00:00:00
abstract::The aim of this paper is to perform a critical review of the effectiveness of interventions for the purpose of enhancing adherence to antiretroviral therapy. The overall evaluation indicates that research is in its early stages. Although pilot studies provide support for the feasibility of their protocols, and prelimi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/0956462053888934
更新日期:2005-05-01 00:00:00